pentetrazol-1408 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

195 genes differentially expressed following the pentetrazol-1408 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
AEN apoptosis enhancing nuclease
AIM2 absent in melanoma 2
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALDOB aldolase B, fructose-bisphosphate
ANKRD12 ankyrin repeat domain 12
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASF1A anti-silencing function 1A histone chaperone
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
AURKA aurora kinase A
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
BAZ2A bromodomain adjacent to zinc finger domain, 2A
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAMKV CaM kinase-like vesicle-associated
CCDC7 coiled-coil domain containing 7
CD6 CD6 molecule
CD82 CD82 molecule
COX5B cytochrome c oxidase subunit Vb
DENND2D DENN/MADD domain containing 2D
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EFR3B EFR3 homolog B (S. cerevisiae)
EIF5B eukaryotic translation initiation factor 5B
EPX eosinophil peroxidase
FAM149B1 family with sequence similarity 149, member B1
FAM76A family with sequence similarity 76, member A
FLJ11710 uncharacterized protein FLJ11710
FLNC filamin C, gamma
GLTP glycolipid transfer protein
GOSR2 golgi SNAP receptor complex member 2
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HBB hemoglobin, beta
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IER3IP1 immediate early response 3 interacting protein 1
IGHM immunoglobulin heavy constant mu
KDM2A lysine (K)-specific demethylase 2A
KIF5C kinesin family member 5C
KLK8 kallikrein-related peptidase 8
LHB luteinizing hormone beta polypeptide
LPAR1 lysophosphatidic acid receptor 1
MYL10 myosin, light chain 10, regulatory
NCAPH2 non-SMC condensin II complex, subunit H2
NDRG2 NDRG family member 2
NIPAL2 NIPA-like domain containing 2
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NLK nemo-like kinase
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
NXPH4 neurexophilin 4
OGFR opioid growth factor receptor
PBX2 pre-B-cell leukemia homeobox 2
PDCD2 programmed cell death 2
PDGFB platelet-derived growth factor beta polypeptide
PGK1 phosphoglycerate kinase 1
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLIN2 perilipin 2
PMCH pro-melanin-concentrating hormone
PMEL premelanosome protein
POLG polymerase (DNA directed), gamma
PRRC2C proline-rich coiled-coil 2C
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RAB2A RAB2A, member RAS oncogene family
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RANBP1 RAN binding protein 1
RANBP17 RAN binding protein 17
RHOH ras homolog family member H
RPAIN RPA interacting protein
RPL14 ribosomal protein L14
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
SAP30 Sin3A-associated protein, 30kDa
SFTPB surfactant protein B
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SYNJ2 synaptojanin 2
SYT1 synaptotagmin I
TCF3 transcription factor 3
TCP10L t-complex 10-like
TCP11L1 t-complex 11, testis-specific-like 1
TK2 thymidine kinase 2, mitochondrial
TRAM1 translocation associated membrane protein 1
TSFM Ts translation elongation factor, mitochondrial
TXN thioredoxin
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VDAC3 voltage-dependent anion channel 3
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
YIPF4 Yip1 domain family, member 4
YLPM1 YLP motif containing 1
YY1 YY1 transcription factor
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACTN4 actinin, alpha 4
ANAPC2 anaphase promoting complex subunit 2
AP1B1 adaptor-related protein complex 1, beta 1 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARFIP2 ADP-ribosylation factor interacting protein 2
ATAD3A ATPase family, AAA domain containing 3A
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AUP1 ancient ubiquitous protein 1
AZU1 azurocidin 1
BANF1 barrier to autointegration factor 1
BANP BTG3 associated nuclear protein
BCORL1 BCL6 corepressor-like 1
C1ORF216 chromosome 1 open reading frame 216
CARD9 caspase recruitment domain family, member 9
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLTCL1 clathrin, heavy chain-like 1
CNPY3 canopy FGF signaling regulator 3
CSK c-src tyrosine kinase
CYC1 cytochrome c-1
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DGKZ diacylglycerol kinase, zeta
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DIXDC1 DIX domain containing 1
E2F8 E2F transcription factor 8
ELANE elastase, neutrophil expressed
FAM173A family with sequence similarity 173, member A
FAM63A family with sequence similarity 63, member A
FES FES proto-oncogene, tyrosine kinase
FGR FGR proto-oncogene, Src family tyrosine kinase
GAK cyclin G associated kinase
GBAS glioblastoma amplified sequence
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GSR glutathione reductase
GTPBP2 GTP binding protein 2
GUSBP3 glucuronidase, beta pseudogene 3
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
IFITM3 interferon induced transmembrane protein 3
KAT2A K(lysine) acetyltransferase 2A
KLHL21 kelch-like family member 21
LACTB2 lactamase, beta 2
LMAN2L lectin, mannose-binding 2-like
LRP10 low density lipoprotein receptor-related protein 10
LSP1 lymphocyte-specific protein 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAGT1 magnesium transporter 1
MCRS1 microspherule protein 1
MFSD10 major facilitator superfamily domain containing 10
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NT5DC2 5'-nucleotidase domain containing 2
PANK4 pantothenate kinase 4
PFN1 profilin 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PISD phosphatidylserine decarboxylase
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMM1 phosphomannomutase 1
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRTN3 proteinase 3
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAB4B RAB4B, member RAS oncogene family
RALY RALY heterogeneous nuclear ribonucleoprotein
RHOG ras homolog family member G
RING1 ring finger protein 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RUNX1-IT1 RUNX1 intronic transcript 1
SAC3D1 SAC3 domain containing 1
SF3B4 splicing factor 3b, subunit 4, 49kDa
SH3GL1 SH3-domain GRB2-like 1
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SNX17 sorting nexin 17
SSNA1 Sjogren syndrome nuclear autoantigen 1
STXBP2 syntaxin binding protein 2
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TBL3 transducin (beta)-like 3
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TECR trans-2,3-enoyl-CoA reductase
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM115 transmembrane protein 115
TMEM14B transmembrane protein 14B
TMEM39B transmembrane protein 39B
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TRIM28 tripartite motif containing 28
TSTA3 tissue specific transplantation antigen P35B
UBE2M ubiquitin-conjugating enzyme E2M
UQCRC1 ubiquinol-cytochrome c reductase core protein I
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WASF1 WAS protein family, member 1
XPA xeroderma pigmentosum, complementation group A
ZNF140 zinc finger protein 140