pentetrazol-2092 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the pentetrazol-2092 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADRBK2 adrenergic, beta, receptor kinase 2
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALPK1 alpha-kinase 1
APOE apolipoprotein E
ARID1A AT rich interactive domain 1A (SWI-like)
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
C2CD2L C2CD2-like
CACYBP calcyclin binding protein
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD47 CD47 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDK6 cyclin-dependent kinase 6
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLCN4 chloride channel, voltage-sensitive 4
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNTLN centlein, centrosomal protein
COL11A2 collagen, type XI, alpha 2
CPNE7 copine VII
CSF1R colony stimulating factor 1 receptor
CSPP1 centrosome and spindle pole associated protein 1
DBP D site of albumin promoter (albumin D-box) binding protein
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DUSP2 dual specificity phosphatase 2
EGFR epidermal growth factor receptor
FGFR1 fibroblast growth factor receptor 1
FZD1 frizzled class receptor 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GH1 growth hormone 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HHAT hedgehog acyltransferase
HOOK1 hook microtubule-tethering protein 1
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFI6 interferon, alpha-inducible protein 6
INHBA inhibin, beta A
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITGB5 integrin, beta 5
JUND jun D proto-oncogene
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KYNU kynureninase
LINC00652 long intergenic non-protein coding RNA 652
LOC257152 uncharacterized LOC257152
LUZP4 leucine zipper protein 4
MAP3K7CL MAP3K7 C-terminal like
MIIP migration and invasion inhibitory protein
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NR2F2 nuclear receptor subfamily 2, group F, member 2
NT5C 5', 3'-nucleotidase, cytosolic
OASL 2'-5'-oligoadenylate synthetase-like
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PEX5L peroxisomal biogenesis factor 5-like
PHF20 PHD finger protein 20
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PKP3 plakophilin 3
PNMA3 paraneoplastic Ma antigen 3
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PSD4 pleckstrin and Sec7 domain containing 4
PWAR5 Prader Willi/Angelman region RNA 5
PXMP4 peroxisomal membrane protein 4, 24kDa
RAD52 RAD52 homolog (S. cerevisiae)
RALGDS ral guanine nucleotide dissociation stimulator
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RCN3 reticulocalbin 3, EF-hand calcium binding domain
REL v-rel avian reticuloendotheliosis viral oncogene homolog
REST RE1-silencing transcription factor
RNF122 ring finger protein 122
RPL10 ribosomal protein L10
RPL13P5 ribosomal protein L13 pseudogene 5
RUNX3 runt-related transcription factor 3
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMAD4 SMAD family member 4
SOS2 son of sevenless homolog 2 (Drosophila)
SPTB spectrin, beta, erythrocytic
SUGP1 SURP and G patch domain containing 1
TBKBP1 TBK1 binding protein 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TENM4 teneurin transmembrane protein 4
TGIF2 TGFB-induced factor homeobox 2
TMEM63A transmembrane protein 63A
TP63 tumor protein p63
TRAPPC13 trafficking protein particle complex 13
TRIM14 tripartite motif containing 14
TTC39A tetratricopeptide repeat domain 39A
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
WDR62 WD repeat domain 62
WNK1 WNK lysine deficient protein kinase 1
YTHDC2 YTH domain containing 2
ZFHX3 zinc finger homeobox 3

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACKR3 atypical chemokine receptor 3
ACYP2 acylphosphatase 2, muscle type
ADGRG2 adhesion G protein-coupled receptor G2
AEN apoptosis enhancing nuclease
ARL14 ADP-ribosylation factor-like 14
ASTE1 asteroid homolog 1 (Drosophila)
ATAD2B ATPase family, AAA domain containing 2B
BAHD1 bromo adjacent homology domain containing 1
BAK1 BCL2-antagonist/killer 1
BEX1 brain expressed, X-linked 1
BOLA1 bolA family member 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1ORF159 chromosome 1 open reading frame 159
C1ORF56 chromosome 1 open reading frame 56
C6ORF47 chromosome 6 open reading frame 47
C8ORF60 chromosome 8 open reading frame 60
CAPN5 calpain 5
CCL20 chemokine (C-C motif) ligand 20
CENPT centromere protein T
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CINP cyclin-dependent kinase 2 interacting protein
CRYBB2P1 crystallin, beta B2 pseudogene 1
DMBT1 deleted in malignant brain tumors 1
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DUSP8 dual specificity phosphatase 8
EDN1 endothelin 1
EFNA3 ephrin-A3
EHF ets homologous factor
ESRP2 epithelial splicing regulatory protein 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAN1 FANCD2/FANCI-associated nuclease 1
FBXL4 F-box and leucine-rich repeat protein 4
FER fer (fps/fes related) tyrosine kinase
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FKBP10 FK506 binding protein 10, 65 kDa
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GOLGA8B golgin A8 family, member B
GSR glutathione reductase
HDAC4 histone deacetylase 4
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL32 interleukin 32
IRF2BP1 interferon regulatory factor 2 binding protein 1
ISYNA1 inositol-3-phosphate synthase 1
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA0232 KIAA0232
KLHL36 kelch-like family member 36
LIG1 ligase I, DNA, ATP-dependent
LIMS2 LIM and senescent cell antigen-like domains 2
LIN7B lin-7 homolog B (C. elegans)
MAGOHB mago-nashi homolog B (Drosophila)
MAPK12 mitogen-activated protein kinase 12
MBTPS2 membrane-bound transcription factor peptidase, site 2
MED15 mediator complex subunit 15
MFSD11 major facilitator superfamily domain containing 11
MICA MHC class I polypeptide-related sequence A
MID1IP1 MID1 interacting protein 1
MX1 MX dynamin-like GTPase 1
MYL9 myosin, light chain 9, regulatory
NPFFR1 neuropeptide FF receptor 1
NTHL1 nth endonuclease III-like 1 (E. coli)
OSMR oncostatin M receptor
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RAP1GAP2 RAP1 GTPase activating protein 2
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPP25 ribonuclease P/MRP 25kDa subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPATA2L spermatogenesis associated 2-like
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STBD1 starch binding domain 1
TBC1D19 TBC1 domain family, member 19
TEX40 testis expressed 40
THOC1 THO complex 1
TMEM183A transmembrane protein 183A
TMEM8B transmembrane protein 8B
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSKU tsukushi, small leucine rich proteoglycan
TUBA3D tubulin, alpha 3d
TUBG2 tubulin, gamma 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR19 WD repeat domain 19
ZBTB39 zinc finger and BTB domain containing 39
ZNF226 zinc finger protein 226
ZNF692 zinc finger protein 692