| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the pentetrazol-2092 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| APOE | apolipoprotein E |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATP5S | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) |
| C2CD2L | C2CD2-like |
| CACYBP | calcyclin binding protein |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CD47 | CD47 molecule |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CDK6 | cyclin-dependent kinase 6 |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNTLN | centlein, centrosomal protein |
| COL11A2 | collagen, type XI, alpha 2 |
| CPNE7 | copine VII |
| CSF1R | colony stimulating factor 1 receptor |
| CSPP1 | centrosome and spindle pole associated protein 1 |
| DBP | D site of albumin promoter (albumin D-box) binding protein |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DUSP2 | dual specificity phosphatase 2 |
| EGFR | epidermal growth factor receptor |
| FGFR1 | fibroblast growth factor receptor 1 |
| FZD1 | frizzled class receptor 1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GH1 | growth hormone 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HHAT | hedgehog acyltransferase |
| HOOK1 | hook microtubule-tethering protein 1 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IFI6 | interferon, alpha-inducible protein 6 |
| INHBA | inhibin, beta A |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITGB5 | integrin, beta 5 |
| JUND | jun D proto-oncogene |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KYNU | kynureninase |
| LINC00652 | long intergenic non-protein coding RNA 652 |
| LOC257152 | uncharacterized LOC257152 |
| LUZP4 | leucine zipper protein 4 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MIIP | migration and invasion inhibitory protein |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PEX5L | peroxisomal biogenesis factor 5-like |
| PHF20 | PHD finger protein 20 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PKP3 | plakophilin 3 |
| PNMA3 | paraneoplastic Ma antigen 3 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| REST | RE1-silencing transcription factor |
| RNF122 | ring finger protein 122 |
| RPL10 | ribosomal protein L10 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RUNX3 | runt-related transcription factor 3 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SMAD4 | SMAD family member 4 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPTB | spectrin, beta, erythrocytic |
| SUGP1 | SURP and G patch domain containing 1 |
| TBKBP1 | TBK1 binding protein 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TENM4 | teneurin transmembrane protein 4 |
| TGIF2 | TGFB-induced factor homeobox 2 |
| TMEM63A | transmembrane protein 63A |
| TP63 | tumor protein p63 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRIM14 | tripartite motif containing 14 |
| TTC39A | tetratricopeptide repeat domain 39A |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| YTHDC2 | YTH domain containing 2 |
| ZFHX3 | zinc finger homeobox 3 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACKR3 | atypical chemokine receptor 3 |
| ACYP2 | acylphosphatase 2, muscle type |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AEN | apoptosis enhancing nuclease |
| ARL14 | ADP-ribosylation factor-like 14 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATAD2B | ATPase family, AAA domain containing 2B |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BEX1 | brain expressed, X-linked 1 |
| BOLA1 | bolA family member 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CAPN5 | calpain 5 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CENPT | centromere protein T |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DUSP8 | dual specificity phosphatase 8 |
| EDN1 | endothelin 1 |
| EFNA3 | ephrin-A3 |
| EHF | ets homologous factor |
| ESRP2 | epithelial splicing regulatory protein 2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FER | fer (fps/fes related) tyrosine kinase |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GOLGA8B | golgin A8 family, member B |
| GSR | glutathione reductase |
| HDAC4 | histone deacetylase 4 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL32 | interleukin 32 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KIAA0232 | KIAA0232 |
| KLHL36 | kelch-like family member 36 |
| LIG1 | ligase I, DNA, ATP-dependent |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LIN7B | lin-7 homolog B (C. elegans) |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MAPK12 | mitogen-activated protein kinase 12 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MED15 | mediator complex subunit 15 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MICA | MHC class I polypeptide-related sequence A |
| MID1IP1 | MID1 interacting protein 1 |
| MX1 | MX dynamin-like GTPase 1 |
| MYL9 | myosin, light chain 9, regulatory |
| NPFFR1 | neuropeptide FF receptor 1 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| OSMR | oncostatin M receptor |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPATA2L | spermatogenesis associated 2-like |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
| STAG3 | stromal antigen 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STBD1 | starch binding domain 1 |
| TBC1D19 | TBC1 domain family, member 19 |
| TEX40 | testis expressed 40 |
| THOC1 | THO complex 1 |
| TMEM183A | transmembrane protein 183A |
| TMEM8B | transmembrane protein 8B |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TUBA3D | tubulin, alpha 3d |
| TUBG2 | tubulin, gamma 2 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR19 | WD repeat domain 19 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF226 | zinc finger protein 226 |
| ZNF692 | zinc finger protein 692 |