pentolinium Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

40 genes differentially expressed following the pentolinium small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
EPHB2 EPH receptor B2 10.0466
EPHA3 EPH receptor A3 4.10232
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 4.0949
MARCKSL1 MARCKS-like 1 3.94769
CDHR1 cadherin-related family member 1 3.69787
SLC26A4 solute carrier family 26 (anion exchanger), member 4 3.64279
TEX28 testis expressed 28 3.59577
CRYGA crystallin, gamma A 3.59519
DGKQ diacylglycerol kinase, theta 110kDa 3.48839
NKX3-2 NK3 homeobox 2 3.47223
BFSP2 beaded filament structural protein 2, phakinin 3.37539
GPA33 glycoprotein A33 (transmembrane) 3.34074
NEUROD4 neuronal differentiation 4 3.33782
HROB homologous recombination factor with OB-fold 3.31413
GUCY2C guanylate cyclase 2C 3.30583
EPS8L3 EPS8-like 3 3.29618
MUC2 mucin 2, oligomeric mucus/gel-forming 3.25874
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 3.19295
CCDC70 coiled-coil domain containing 70 3.18662
OLFM4 olfactomedin 4 3.17647
HDAC1 histone deacetylase 1 3.14734
GDF9 growth differentiation factor 9 3.13548
COL13A1 collagen, type XIII, alpha 1 3.09091
SMAD9 SMAD family member 9 3.07715
FOXB1 forkhead box B1 3.03213
TPSG1 tryptase gamma 1 3.02951
SOX21 SRY (sex determining region Y)-box 21 3.02165
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8 3.01649
ECEL1 endothelin converting enzyme-like 1 3.00298
PPIEL peptidylprolyl isomerase E-like pseudogene 3.0026

decreased expression

Symbol Name Standardized Value
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -3.75346
CASP10 caspase 10, apoptosis-related cysteine peptidase -3.68317
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -3.4337
MIA2 melanoma inhibitory activity 2 -3.30041
GP1BB glycoprotein Ib (platelet), beta polypeptide -3.24969
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.16481
COQ8A coenzyme Q8A -3.11538
SIRT3 sirtuin 3 -3.0999
TCAP titin-cap -3.04395
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 -3.02387