pentolonium-3676 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the pentolonium-3676 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ACO2 aconitase 2, mitochondrial
ADAM8 ADAM metallopeptidase domain 8
ADRBK1 adrenergic, beta, receptor kinase 1
ANXA10 annexin A10
APAF1 apoptotic peptidase activating factor 1
APCS amyloid P component, serum
C1ORF61 chromosome 1 open reading frame 61
C21ORF2 chromosome 21 open reading frame 2
CARD10 caspase recruitment domain family, member 10
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCND2 cyclin D2
CDC14A cell division cycle 14A
CHN2 chimerin 2
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLIC5 chloride intracellular channel 5
CNTNAP2 contactin associated protein-like 2
COL17A1 collagen, type XVII, alpha 1
COMT catechol-O-methyltransferase
CST1 cystatin SN
CYBA cytochrome b-245, alpha polypeptide
DGKB diacylglycerol kinase, beta 90kDa
DHRS12 dehydrogenase/reductase (SDR family) member 12
DNASE1L2 deoxyribonuclease I-like 2
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPF1 D4, zinc and double PHD fingers family 1
DRD2 dopamine receptor D2
EPB41L1 erythrocyte membrane protein band 4.1-like 1
ERGIC3 ERGIC and golgi 3
FABP7 fatty acid binding protein 7, brain
FAM63A family with sequence similarity 63, member A
FGF4 fibroblast growth factor 4
FGFR4 fibroblast growth factor receptor 4
FOSL2 FOS-like antigen 2
GGT1 gamma-glutamyltransferase 1
HAO2 hydroxyacid oxidase 2 (long chain)
HFE hemochromatosis
HIST3H3 histone cluster 3, H3
HLA-DOA major histocompatibility complex, class II, DO alpha
HN1L hematological and neurological expressed 1-like
HOXB1 homeobox B1
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IBSP integrin-binding sialoprotein
IFNA14 interferon, alpha 14
IGLJ3 immunoglobulin lambda joining 3
IL17RC interleukin 17 receptor C
IL32 interleukin 32
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KLHL18 kelch-like family member 18
KLHL29 kelch-like family member 29
KLK10 kallikrein-related peptidase 10
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KSR1 kinase suppressor of ras 1
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MEF2D myocyte enhancer factor 2D
MNMIP1 manchette microtubule inner protein 1
MYOZ3 myozenin 3
N4BP1 NEDD4 binding protein 1
N4BP2L1 NEDD4 binding protein 2-like 1
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NRDE2 NRDE-2, necessary for RNA interference, domain containing
OXCT2 3-oxoacid CoA transferase 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDCD2 programmed cell death 2
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE8B phosphodiesterase 8B
PHF8 PHD finger protein 8
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PML promyelocytic leukemia
PRB1 proline-rich protein BstNI subfamily 1
PRKCE protein kinase C, epsilon
PSCA prostate stem cell antigen
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAD51B RAD51 paralog B
RAG1 recombination activating gene 1
RND1 Rho family GTPase 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SNX29 sorting nexin 29
SORT1 sortilin 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTBN4 spectrin, beta, non-erythrocytic 4
STATH statherin
TAT tyrosine aminotransferase
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1
TRAC T cell receptor alpha constant
TRIM3 tripartite motif containing 3
USP29 ubiquitin specific peptidase 29
WDR59 WD repeat domain 59
ZBTB7A zinc finger and BTB domain containing 7A
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF154 zinc finger protein 154

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ADTRP androgen-dependent TFPI-regulating protein
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AMPD2 adenosine monophosphate deaminase 2
ANAPC2 anaphase promoting complex subunit 2
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APOL6 apolipoprotein L, 6
ARC activity-regulated cytoskeleton-associated protein
ARHGAP22 Rho GTPase activating protein 22
ARSB arylsulfatase B
ATG2B autophagy related 2B
AURKC aurora kinase C
C17ORF53 chromosome 17 open reading frame 53
C1ORF115 chromosome 1 open reading frame 115
C1QTNF1 C1q and tumor necrosis factor related protein 1
C1QTNF3 C1q and tumor necrosis factor related protein 3
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C9ORF9 chromosome 9 open reading frame 9
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CBY1 chibby homolog 1 (Drosophila)
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNTFR ciliary neurotrophic factor receptor
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DEAF1 DEAF1 transcription factor
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DUSP2 dual specificity phosphatase 2
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EXOC6B exocyst complex component 6B
FANCE Fanconi anemia, complementation group E
FBXL7 F-box and leucine-rich repeat protein 7
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FMO4 flavin containing monooxygenase 4
GEMIN8 gem (nuclear organelle) associated protein 8
GJA8 gap junction protein, alpha 8, 50kDa
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
HDAC9 histone deacetylase 9
HOXB2 homeobox B2
HOXC11 homeobox C11
IFI6 interferon, alpha-inducible protein 6
IL22 interleukin 22
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0355 KIAA0355
KIAA1107 KIAA1107
LIME1 Lck interacting transmembrane adaptor 1
LRRC61 leucine rich repeat containing 61
LRRK1 leucine-rich repeat kinase 1
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAK male germ cell-associated kinase
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP3 matrix metallopeptidase 3
MTA2 metastasis associated 1 family, member 2
NPFFR1 neuropeptide FF receptor 1
ODF2 outer dense fiber of sperm tails 2
PADI1 peptidyl arginine deiminase, type I
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLSCR4 phospholipid scramblase 4
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRF1 perforin 1 (pore forming protein)
PRR15L proline rich 15-like
PTK6 protein tyrosine kinase 6
PTPRU protein tyrosine phosphatase, receptor type, U
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHOBTB2 Rho-related BTB domain containing 2
ROM1 retinal outer segment membrane protein 1
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
S100A3 S100 calcium binding protein A3
SCUBE3 signal peptide, CUB domain, EGF-like 3
SIRAL2 SIR2 antiphage like 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SLN sarcolipin
SMO smoothened, frizzled class receptor
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
STAB2 stabilin 2
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SYNGR3 synaptogyrin 3
TINAGL1 tubulointerstitial nephritis antigen-like 1
TLR2 toll-like receptor 2
TMC5 transmembrane channel-like 5
TMEM180 transmembrane protein 180
TMEM8A transmembrane protein 8A
TMSB15A thymosin beta 15a
TRABD TraB domain containing
TTLL7 tubulin tyrosine ligase-like family member 7
ZC3H12A zinc finger CCCH-type containing 12A
ZNF214 zinc finger protein 214
ZNF506 zinc finger protein 506
ZNF639 zinc finger protein 639
ZNF701 zinc finger protein 701