| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the pentolonium-7375 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ACRV1 | acrosomal vesicle protein 1 |
| ADCK2 | aarF domain containing kinase 2 |
| ALAD | aminolevulinate dehydratase |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| AMACR | alpha-methylacyl-CoA racemase |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BTC | betacellulin |
| C6ORF10 | chromosome 6 open reading frame 10 |
| CABIN1 | calcineurin binding protein 1 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CBX4 | chromobox homolog 4 |
| CDHR2 | cadherin-related family member 2 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLDN11 | claudin 11 |
| CRY2 | cryptochrome circadian clock 2 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CUL7 | cullin 7 |
| DOCK5 | dedicator of cytokinesis 5 |
| DOCK6 | dedicator of cytokinesis 6 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase |
| DOK5 | docking protein 5 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DUSP1 | dual specificity phosphatase 1 |
| E2F1 | E2F transcription factor 1 |
| EDNRB | endothelin receptor type B |
| EFNA3 | ephrin-A3 |
| EFS | embryonal Fyn-associated substrate |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| EMP1 | epithelial membrane protein 1 |
| FAM120C | family with sequence similarity 120C |
| GLRX3 | glutaredoxin 3 |
| GPR135 | G protein-coupled receptor 135 |
| GREM2 | gremlin 2, DAN family BMP antagonist |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HNF1B | HNF1 homeobox B |
| HSF2BP | heat shock transcription factor 2 binding protein |
| IFT27 | intraflagellar transport 27 |
| IKBKAP | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
| IL17RA | interleukin 17 receptor A |
| ITGB8 | integrin, beta 8 |
| JMJD6 | jumonji domain containing 6 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| LMF2 | lipase maturation factor 2 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRK1 | leucine-rich repeat kinase 1 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MED16 | mediator complex subunit 16 |
| METTL7A | methyltransferase like 7A |
| MIIP | migration and invasion inhibitory protein |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| NAAA | N-acylethanolamine acid amidase |
| NAIP | NLR family, apoptosis inhibitory protein |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PMP2 | peripheral myelin protein 2 |
| PRKCE | protein kinase C, epsilon |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| R3HDM1 | R3H domain containing 1 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RPL5 | ribosomal protein L5 |
| RUNX1 | runt-related transcription factor 1 |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| SAPCD1 | suppressor APC domain containing 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SETD1A | SET domain containing 1A |
| SHROOM2 | shroom family member 2 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SND1-IT1 | SND1 intronic transcript 1 |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TGFB1 | transforming growth factor, beta 1 |
| THBS3 | thrombospondin 3 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEM63A | transmembrane protein 63A |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TSFM | Ts translation elongation factor, mitochondrial |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF141 | zinc finger protein 141 |
| ZNF197 | zinc finger protein 197 |
| ZNF606 | zinc finger protein 606 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AFAP1 | actin filament associated protein 1 |
| ALS2CL | ALS2 C-terminal like |
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARMC6 | armadillo repeat containing 6 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BAG4 | BCL2-associated athanogene 4 |
| BAK1 | BCL2-antagonist/killer 1 |
| BCL9 | B-cell CLL/lymphoma 9 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CBX8 | chromobox homolog 8 |
| CDH7 | cadherin 7, type 2 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CENPO | centromere protein O |
| CLEC10A | C-type lectin domain family 10, member A |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CTSK | cathepsin K |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| CYTH2 | cytohesin 2 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DSN1 | DSN1, MIS12 kinetochore complex component |
| DTWD1 | DTW domain containing 1 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EMD | emerin |
| EPN3 | epsin 3 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EVPL | envoplakin |
| FAM53B | family with sequence similarity 53, member B |
| FCHO1 | FCH domain only 1 |
| FOXA1 | forkhead box A1 |
| FUBP3 | far upstream element (FUSE) binding protein 3 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GTPBP2 | GTP binding protein 2 |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HIST1H2AM | histone cluster 1, H2am |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LHX6 | LIM homeobox 6 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 |
| MRPL46 | mitochondrial ribosomal protein L46 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NMB | neuromedin B |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PLCD1 | phospholipase C, delta 1 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF31 | ring finger protein 31 |
| SCARA3 | scavenger receptor class A, member 3 |
| SETD6 | SET domain containing 6 |
| SH3GL2 | SH3-domain GRB2-like 2 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SNTA1 | syntrophin, alpha 1 |
| SNX10 | sorting nexin 10 |
| SP140L | SP140 nuclear body protein-like |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TMEM159 | transmembrane protein 159 |
| TMEM2 | transmembrane protein 2 |
| TMEM209 | transmembrane protein 209 |
| TMEM38B | transmembrane protein 38B |
| TMEM80 | transmembrane protein 80 |
| TMEM8B | transmembrane protein 8B |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TRIM9 | tripartite motif containing 9 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TWF2 | twinfilin actin binding protein 2 |
| UBTD1 | ubiquitin domain containing 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR18 | WD repeat domain 18 |
| ZNF34 | zinc finger protein 34 |
| ZNF552 | zinc finger protein 552 |
| ZNF671 | zinc finger protein 671 |
| ZNF816 | zinc finger protein 816 |