| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the pentoxifylline-1444 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ADM2 | adrenomedullin 2 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| API5 | apoptosis inhibitor 5 |
| ARMC7 | armadillo repeat containing 7 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| CA14 | carbonic anhydrase XIV |
| CAPN3 | calpain 3, (p94) |
| CD320 | CD320 molecule |
| CDC25A | cell division cycle 25A |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CEP152 | centrosomal protein 152kDa |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DIO2 | deiodinase, iodothyronine, type II |
| DMC1 | DNA meiotic recombinase 1 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM102A | family with sequence similarity 102, member A |
| FBXO31 | F-box protein 31 |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FGGY | FGGY carbohydrate kinase domain containing |
| FST | follistatin |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 |
| GRM2 | glutamate receptor, metabotropic 2 |
| GYG2 | glycogenin 2 |
| HDAC5 | histone deacetylase 5 |
| HFE | hemochromatosis |
| HIST1H4J | histone cluster 1, H4j |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ISCA1 | iron-sulfur cluster assembly 1 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KLF6 | Kruppel-like factor 6 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LIMD2 | LIM domain containing 2 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LPAR1 | lysophosphatidic acid receptor 1 |
| MAP4 | microtubule-associated protein 4 |
| MECP2 | methyl CpG binding protein 2 |
| MED16 | mediator complex subunit 16 |
| MED28 | mediator complex subunit 28 |
| MERTK | MER proto-oncogene, tyrosine kinase |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| METTL13 | methyltransferase like 13 |
| MINK1 | misshapen-like kinase 1 |
| MMP19 | matrix metallopeptidase 19 |
| MPPE1 | metallophosphoesterase 1 |
| MST1 | macrophage stimulating 1 |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NAGLU | N-acetylglucosaminidase, alpha |
| NCDN | neurochondrin |
| NF1 | neurofibromin 1 |
| NIPSNAP3B | nipsnap homolog 3B (C. elegans) |
| NMD3 | NMD3 ribosome export adaptor |
| NOTCH2 | notch 2 |
| OCRL | oculocerebrorenal syndrome of Lowe |
| PARG | poly (ADP-ribose) glycohydrolase |
| PLEK2 | pleckstrin 2 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha |
| RAB11B | RAB11B, member RAS oncogene family |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| RYK | receptor-like tyrosine kinase |
| SIRT6 | sirtuin 6 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLC6A12 | solute carrier family 6 (neurotransmitter transporter), member 12 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SPTB | spectrin, beta, erythrocytic |
| STAP2 | signal transducing adaptor family member 2 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TRMT61A | tRNA methyltransferase 61A |
| TUBB3 | tubulin, beta 3 class III |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| URI1 | URI1, prefoldin-like chaperone |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| VWA8 | von Willebrand factor A domain containing 8 |
| ZNF236 | zinc finger protein 236 |
| ZNF473 | zinc finger protein 473 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| AACS | acetoacetyl-CoA synthetase |
| ACVR2B | activin A receptor, type IIB |
| ACYP2 | acylphosphatase 2, muscle type |
| ADAM9 | ADAM metallopeptidase domain 9 |
| ANKRD36B | ankyrin repeat domain 36B |
| ASB8 | ankyrin repeat and SOCS box containing 8 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BCL2L2 | BCL2-like 2 |
| BCL7C | B-cell CLL/lymphoma 7C |
| BTK | Bruton agammaglobulinemia tyrosine kinase |
| CCDC130 | coiled-coil domain containing 130 |
| CCDC51 | coiled-coil domain containing 51 |
| CDC37 | cell division cycle 37 |
| CENPT | centromere protein T |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CPOX | coproporphyrinogen oxidase |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DENND4A | DENN/MADD domain containing 4A |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DPYD | dihydropyrimidine dehydrogenase |
| EDAR | ectodysplasin A receptor |
| ERI3 | ERI1 exoribonuclease family member 3 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FBXO5 | F-box protein 5 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FES | FES proto-oncogene, tyrosine kinase |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| FUBP3 | far upstream element (FUSE) binding protein 3 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| IL2RG | interleukin 2 receptor, gamma |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KIF3B | kinesin family member 3B |
| KIFAP3 | kinesin-associated protein 3 |
| KIFC1 | kinesin family member C1 |
| KLF13 | Kruppel-like factor 13 |
| LIN37 | lin-37 DREAM MuvB core complex component |
| LOC100272216 | uncharacterized LOC100272216 |
| LSP1 | lymphocyte-specific protein 1 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MAP1S | microtubule-associated protein 1S |
| MED4 | mediator complex subunit 4 |
| MPHOSPH8 | M-phase phosphoprotein 8 |
| MSN | moesin |
| NABP2 | nucleic acid binding protein 2 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NUPL1 | nucleoporin like 1 |
| NXPH3 | neurexophilin 3 |
| OBFC1 | oligonucleotide/oligosaccharide-binding fold containing 1 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit |
| POLI | polymerase (DNA directed) iota |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PRMT3 | protein arginine methyltransferase 3 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RAB4B | RAB4B, member RAS oncogene family |
| RABL3 | RAB, member of RAS oncogene family-like 3 |
| RAD9A | RAD9 homolog A (S. pombe) |
| RBL1 | retinoblastoma-like 1 |
| RBM47 | RNA binding motif protein 47 |
| RHOF | ras homolog family member F (in filopodia) |
| RNF170 | ring finger protein 170 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| RSF1 | remodeling and spacing factor 1 |
| RWDD3 | RWD domain containing 3 |
| SFMBT1 | Scm-like with four mbt domains 1 |
| SH2B2 | SH2B adaptor protein 2 |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SKI | SKI proto-oncogene |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SPX | spexin hormone |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| THAP1 | THAP domain containing, apoptosis associated protein 1 |
| TMBIM4 | transmembrane BAX inhibitor motif containing 4 |
| TMEM14A | transmembrane protein 14A |
| TMEM177 | transmembrane protein 177 |
| TMEM186 | transmembrane protein 186 |
| TRAC | T cell receptor alpha constant |
| TRIM8 | tripartite motif containing 8 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TSLIG2 | tRNA splicing ligase complex subunit 2 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VAMP7 | vesicle-associated membrane protein 7 |
| XAF1 | XIAP associated factor 1 |
| XBP1 | X-box binding protein 1 |
| ZEB2 | zinc finger E-box binding homeobox 2 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF140 | zinc finger protein 140 |
| ZNF302 | zinc finger protein 302 |
| ZNF606 | zinc finger protein 606 |
