| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the pentoxifylline-2127 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ACOT11 | acyl-CoA thioesterase 11 |
| ADCY6 | adenylate cyclase 6 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| AURKA | aurora kinase A |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BCR | breakpoint cluster region |
| BTG2 | BTG family, member 2 |
| BTN2A1 | butyrophilin, subfamily 2, member A1 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COBL | cordon-bleu WH2 repeat protein |
| COL6A2 | collagen, type VI, alpha 2 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CUL7 | cullin 7 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| DZIP1 | DAZ interacting zinc finger protein 1 |
| EFNA1 | ephrin-A1 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ESRRA | estrogen-related receptor alpha |
| FASTKD2 | FAST kinase domains 2 |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FGFR1 | fibroblast growth factor receptor 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPC4 | glypican 4 |
| HNF1B | HNF1 homeobox B |
| HOOK1 | hook microtubule-tethering protein 1 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFI44L | interferon-induced protein 44-like |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IL6ST | interleukin 6 signal transducer |
| JAK2 | Janus kinase 2 |
| JUND | jun D proto-oncogene |
| KIAA0232 | KIAA0232 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MCCC2 | methylcrotonoyl-CoA carboxylase 2 (beta) |
| MDFI | MyoD family inhibitor |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MIIP | migration and invasion inhibitory protein |
| MR1 | major histocompatibility complex, class I-related |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOL12 | nucleolar protein 12 |
| NUP50 | nucleoporin 50kDa |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PDLIM4 | PDZ and LIM domain 4 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PHF1 | PHD finger protein 1 |
| PHTF2 | putative homeodomain transcription factor 2 |
| PIDD1 | p53-induced death domain protein 1 |
| PLK3 | polo-like kinase 3 |
| PNISR | PNN-interacting serine/arginine-rich protein |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| RAI2 | retinoic acid induced 2 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RBM4 | RNA binding motif protein 4 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RREB1 | ras responsive element binding protein 1 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SEC63 | SEC63 homolog (S. cerevisiae) |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SMAD5 | SMAD family member 5 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| STX2 | syntaxin 2 |
| SYCP2 | synaptonemal complex protein 2 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TBCD | tubulin folding cofactor D |
| TCTN1 | tectonic family member 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TLR2 | toll-like receptor 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TOP3B | topoisomerase (DNA) III beta |
| TRAFD1 | TRAF-type zinc finger domain containing 1 |
| TRIM29 | tripartite motif containing 29 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF10 | zinc finger protein 10 |
| ZNF580 | zinc finger protein 580 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ANKRD40 | ankyrin repeat domain 40 |
| APH1B | APH1B gamma secretase subunit |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCDC106 | coiled-coil domain containing 106 |
| CCNJL | cyclin J-like |
| CCNT1 | cyclin T1 |
| CD70 | CD70 molecule |
| CD82 | CD82 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLEC2B | C-type lectin domain family 2, member B |
| CLSPN | claspin |
| CNTNAP3B | contactin associated protein-like 3B |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DEAF1 | DEAF1 transcription factor |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EDAR | ectodysplasin A receptor |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EN1 | engrailed homeobox 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPHB6 | EPH receptor B6 |
| FMO4 | flavin containing monooxygenase 4 |
| FPGS | folylpolyglutamate synthase |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GALK1 | galactokinase 1 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H3G | histone cluster 1, H3g |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HS1BP3 | HCLS1 binding protein 3 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IFT54 | intraflagellar transport 54 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IREB2 | iron-responsive element binding protein 2 |
| JAM3 | junctional adhesion molecule 3 |
| KCNJ12 | potassium channel, inwardly rectifying subfamily J, member 12 |
| LMNB1 | lamin B1 |
| LOC257152 | uncharacterized LOC257152 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LY96 | lymphocyte antigen 96 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MPI | mannose phosphate isomerase |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| NXPH4 | neurexophilin 4 |
| OLFML2A | olfactomedin-like 2A |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| POLH | polymerase (DNA directed), eta |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PRSS22 | protease, serine, 22 |
| PRSS53 | protease, serine, 53 |
| QSER1 | glutamine and serine rich 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RIN1 | Ras and Rab interactor 1 |
| RNF2 | ring finger protein 2 |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCARA3 | scavenger receptor class A, member 3 |
| SIRT2 | sirtuin 2 |
| SLC12A8 | solute carrier family 12, member 8 |
| SMA4 | glucuronidase, beta pseudogene |
| STAC | SH3 and cysteine rich domain |
| STEAP4 | STEAP family member 4 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TEAD3 | TEA domain family member 3 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM45 | tripartite motif containing 45 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TUBA3D | tubulin, alpha 3d |
| WDR18 | WD repeat domain 18 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF32 | zinc finger protein 32 |
| ZNF606 | zinc finger protein 606 |
| ZNF84 | zinc finger protein 84 |
| ZNF862 | zinc finger protein 862 |
