| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the pentoxifylline-6021 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ANGEL2 | angel homolog 2 (Drosophila) |
| APP | amyloid beta (A4) precursor protein |
| ATP10B | ATPase, class V, type 10B |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
| BIN1 | bridging integrator 1 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CCDC64 | coiled-coil domain containing 64 |
| CGA | glycoprotein hormones, alpha polypeptide |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CUL7 | cullin 7 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP6 | dual specificity phosphatase 6 |
| EDN3 | endothelin 3 |
| EMID1 | EMI domain containing 1 |
| EPHB2 | EPH receptor B2 |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) |
| FADS3 | fatty acid desaturase 3 |
| FAM134B | family with sequence similarity 134, member B |
| FCGBP | Fc fragment of IgG binding protein |
| FMO5 | flavin containing monooxygenase 5 |
| G6PC3 | glucose 6 phosphatase, catalytic, 3 |
| GAB1 | GRB2-associated binding protein 1 |
| GGT1 | gamma-glutamyltransferase 1 |
| GLS | glutaminase |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GNRHR | gonadotropin-releasing hormone receptor |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR137 | G protein-coupled receptor 137 |
| HIST1H2BM | histone cluster 1, H2bm |
| HIST1H4H | histone cluster 1, H4h |
| IFI35 | interferon-induced protein 35 |
| IL4R | interleukin 4 receptor |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIF25 | kinesin family member 25 |
| LAMC2 | laminin, gamma 2 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LOXL3 | lysyl oxidase-like 3 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MDM4 | MDM4, p53 regulator |
| MED16 | mediator complex subunit 16 |
| METTL16 | methyltransferase like 16 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MYBPC3 | myosin binding protein C, cardiac |
| MYO9B | myosin IXB |
| NMT1 | N-myristoyltransferase 1 |
| NOL12 | nucleolar protein 12 |
| NUP214 | nucleoporin 214kDa |
| OSBPL10 | oxysterol binding protein-like 10 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| POPDC3 | popeye domain containing 3 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PRKCA | protein kinase C, alpha |
| PRLR | prolactin receptor |
| PRR5 | proline rich 5 (renal) |
| RAD54B | RAD54 homolog B (S. cerevisiae) |
| RECQL5 | RecQ protein-like 5 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF208 | ring finger protein 208 |
| RNF39 | ring finger protein 39 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S100A2 | S100 calcium binding protein A2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC17A2 | solute carrier family 17, member 2 |
| SNN | stannin |
| SNX13 | sorting nexin 13 |
| SPHK2 | sphingosine kinase 2 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STATH | statherin |
| SUGP1 | SURP and G patch domain containing 1 |
| TAPBP | TAP binding protein (tapasin) |
| TCF25 | transcription factor 25 (basic helix-loop-helix) |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TIMM17A | translocase of inner mitochondrial membrane 17 homolog A (yeast) |
| TM2D1 | TM2 domain containing 1 |
| TONSL | tonsoku-like, DNA repair protein |
| TPMT | thiopurine S-methyltransferase |
| TRIM3 | tripartite motif containing 3 |
| TSC22D2 | TSC22 domain family, member 2 |
| TUBA3C | tubulin, alpha 3c |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WNT6 | wingless-type MMTV integration site family, member 6 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF362 | zinc finger protein 362 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF419 | zinc finger protein 419 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACTA1 | actin, alpha 1, skeletal muscle |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AFAP1 | actin filament associated protein 1 |
| ALPK1 | alpha-kinase 1 |
| AMH | anti-Mullerian hormone |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ARRB1 | arrestin, beta 1 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CD83 | CD83 molecule |
| CDON | cell adhesion associated, oncogene regulated |
| CHKB | choline kinase beta |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CST4 | cystatin S |
| CXXC4 | CXXC finger protein 4 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DRD1 | dopamine receptor D1 |
| DSPP | dentin sialophosphoprotein |
| EFNA3 | ephrin-A3 |
| FADS2 | fatty acid desaturase 2 |
| FAM46C | family with sequence similarity 46, member C |
| FGL1 | fibrinogen-like 1 |
| FLCN | folliculin |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPR3 | G protein-coupled receptor 3 |
| HOXD11 | homeobox D11 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IQCG | IQ motif containing G |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KIAA0319L | KIAA0319-like |
| KIAA0894 | KIAA0894 protein |
| LIN7B | lin-7 homolog B (C. elegans) |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LOC729164 | hCG1732469 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| LTC4S | leukotriene C4 synthase |
| MEGF8 | multiple EGF-like-domains 8 |
| MITF | microphthalmia-associated transcription factor |
| MMP2 | matrix metallopeptidase 2 |
| MRAS | muscle RAS oncogene homolog |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NAG18 | NAG18 mRNA |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NIPAL2 | NIPA-like domain containing 2 |
| NKX3-2 | NK3 homeobox 2 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NXPH4 | neurexophilin 4 |
| OSMR | oncostatin M receptor |
| PCDHA5 | protocadherin alpha 5 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PLA2G3 | phospholipase A2, group III |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| POM121 | POM121 transmembrane nucleoporin |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRF1 | perforin 1 (pore forming protein) |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RFXAP | regulatory factor X-associated protein |
| RGS2 | regulator of G-protein signaling 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SDC3 | syndecan 3 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SOX12 | SRY (sex determining region Y)-box 12 |
| TBX19 | T-box 19 |
| TDRD1 | tudor domain containing 1 |
| THBS3 | thrombospondin 3 |
| TMEM212 | transmembrane protein 212 |
| UNC119 | unc-119 homolog (C. elegans) |
| VASH1 | vasohibin 1 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VNN2 | vanin 2 |
| XK | X-linked Kx blood group |
| ZFP37 | ZFP37 zinc finger protein |
| ZNF652 | zinc finger protein 652 |
