| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
198 genes differentially expressed following the pentoxifylline-7319 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ACVR1B | activin A receptor, type IB |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALPK1 | alpha-kinase 1 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| APC | adenomatous polyposis coli |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ARTN | artemin |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| CADM3 | cell adhesion molecule 3 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CD6 | CD6 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CIB2 | calcium and integrin binding family member 2 |
| CSPP1 | centrosome and spindle pole associated protein 1 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DENND4A | DENN/MADD domain containing 4A |
| DUSP10 | dual specificity phosphatase 10 |
| DUSP8 | dual specificity phosphatase 8 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EPPK1 | epiplakin 1 |
| ERP44 | endoplasmic reticulum protein 44 |
| FAM188A | family with sequence similarity 188, member A |
| FAM63B | family with sequence similarity 63, member B |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FOXG1 | forkhead box G1 |
| GLRX3 | glutaredoxin 3 |
| GPR107 | G protein-coupled receptor 107 |
| H2AFJ | H2A histone family, member J |
| HHEX | hematopoietically expressed homeobox |
| HNF1B | HNF1 homeobox B |
| HOXA2 | homeobox A2 |
| HOXA4 | homeobox A4 |
| IFFO1 | intermediate filament family orphan 1 |
| IL24 | interleukin 24 |
| IZUMO4 | IZUMO family member 4 |
| JMJD6 | jumonji domain containing 6 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KLHL20 | kelch-like family member 20 |
| LRRC61 | leucine rich repeat containing 61 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MARS | methionyl-tRNA synthetase |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MYRF | myelin regulatory factor |
| NDE1 | nudE neurodevelopment protein 1 |
| NEK11 | NIMA-related kinase 11 |
| NF2 | neurofibromin 2 (merlin) |
| NINJ1 | ninjurin 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OLFML3 | olfactomedin-like 3 |
| OSBP2 | oxysterol binding protein 2 |
| PDCD6 | programmed cell death 6 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDLIM3 | PDZ and LIM domain 3 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RAD51B | RAD51 paralog B |
| RBBP9 | retinoblastoma binding protein 9 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS10 | regulator of G-protein signaling 10 |
| RGS14 | regulator of G-protein signaling 14 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SRSF6 | serine/arginine-rich splicing factor 6 |
| SYNJ2 | synaptojanin 2 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TAPBP | TAP binding protein (tapasin) |
| TBC1D22A | TBC1 domain family, member 22A |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 |
| TLE3 | transducin-like enhancer of split 3 |
| TMEM53 | transmembrane protein 53 |
| TMEM63A | transmembrane protein 63A |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TPM2 | tropomyosin 2 (beta) |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TUBA4B | tubulin, alpha 4b |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| VWA5A | von Willebrand factor A domain containing 5A |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| AEN | apoptosis enhancing nuclease |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| APOC1 | apolipoprotein C-I |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF9 | Cdc42 guanine nucleotide exchange factor (GEF) 9 |
| ATP10D | ATPase, class V, type 10D |
| ATXN2 | ataxin 2 |
| BAK1 | BCL2-antagonist/killer 1 |
| BEX1 | brain expressed, X-linked 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C11ORF71 | chromosome 11 open reading frame 71 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) |
| CCDC68 | coiled-coil domain containing 68 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CDKN2AIP | CDKN2A interacting protein |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CNN2 | calponin 2 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DCP1A | decapping mRNA 1A |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| EAF2 | ELL associated factor 2 |
| EFNA3 | ephrin-A3 |
| EGF | epidermal growth factor |
| ERCC2 | excision repair cross-complementation group 2 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FIG4 | FIG4 phosphoinositide 5-phosphatase |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GPATCH2L | G patch domain containing 2-like |
| HIST1H4D | histone cluster 1, H4d |
| HOXC8 | homeobox C8 |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KLHL3 | kelch-like family member 3 |
| MANBA | mannosidase, beta A, lysosomal |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MMP9 | matrix metallopeptidase 9 |
| MOXD1 | monooxygenase, DBH-like 1 |
| MPI | mannose phosphate isomerase |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MXRA8 | matrix-remodelling associated 8 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NFS1 | NFS1 cysteine desulfurase |
| OGDHL | oxoglutarate dehydrogenase-like |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDGFRL | platelet-derived growth factor receptor-like |
| PLA2G15 | phospholipase A2, group XV |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PSKH1 | protein serine kinase H1 |
| RAD51AP1 | RAD51 associated protein 1 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPAP2 | RNA polymerase II associated protein 2 |
| SALL2 | spalt-like transcription factor 2 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| STAR | steroidogenic acute regulatory protein |
| STK16 | serine/threonine kinase 16 |
| TMEM183A | transmembrane protein 183A |
| TMEM19 | transmembrane protein 19 |
| TMEM212 | transmembrane protein 212 |
| TMEM62 | transmembrane protein 62 |
| TMEM8B | transmembrane protein 8B |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TNNI3 | troponin I type 3 (cardiac) |
| TRABD | TraB domain containing |
| TSKU | tsukushi, small leucine rich proteoglycan |
| USP6NL | USP6 N-terminal like |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WDR91 | WD repeat domain 91 |
| WFS1 | Wolfram syndrome 1 (wolframin) |
| YY2 | YY2 transcription factor |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF273 | zinc finger protein 273 |
| ZNF510 | zinc finger protein 510 |
| ZNF668 | zinc finger protein 668 |
