pentoxyverine-1268 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the pentoxyverine-1268 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX3 acyl-CoA oxidase 3, pristanoyl
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
BIN1 bridging integrator 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C1RL complement component 1, r subcomponent-like
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CAPN5 calpain 5
CASP10 caspase 10, apoptosis-related cysteine peptidase
CDADC1 cytidine and dCMP deaminase domain containing 1
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CINP cyclin-dependent kinase 2 interacting protein
CISH cytokine inducible SH2-containing protein
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
COMT catechol-O-methyltransferase
COX4I1 cytochrome c oxidase subunit IV isoform 1
CRABP2 cellular retinoic acid binding protein 2
DALRD3 DALR anticodon binding domain containing 3
DDAH2 dimethylarginine dimethylaminohydrolase 2
ELP6 elongator acetyltransferase complex subunit 6
EML3 echinoderm microtubule associated protein like 3
EXT1 exostosin glycosyltransferase 1
FAM127B family with sequence similarity 127, member B
FAM134B family with sequence similarity 134, member B
FAM188A family with sequence similarity 188, member A
FAM3A family with sequence similarity 3, member A
FOXO4 forkhead box O4
FST follistatin
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
H2AFX H2A histone family, member X
HEATR6 HEAT repeat containing 6
HK2 hexokinase 2
HRH1 histamine receptor H1
HSF1 heat shock transcription factor 1
HSPA4 heat shock 70kDa protein 4
IL3RA interleukin 3 receptor, alpha (low affinity)
IRF5 interferon regulatory factor 5
IVD isovaleryl-CoA dehydrogenase
JRK Jrk homolog (mouse)
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAOA monoamine oxidase A
MAP2K7 mitogen-activated protein kinase kinase 7
METTL7A methyltransferase like 7A
MKL1 megakaryoblastic leukemia (translocation) 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTRF1L mitochondrial translational release factor 1-like
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYO1C myosin IC
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NPIPB15 nuclear pore complex interacting protein family, member B15
NPPA natriuretic peptide A
NUMA1 nuclear mitotic apparatus protein 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARP3 poly (ADP-ribose) polymerase family, member 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLK3 polo-like kinase 3
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme
PROS1 protein S (alpha)
PTAFR platelet-activating factor receptor
PVT1 Pvt1 oncogene (non-protein coding)
RRP1B ribosomal RNA processing 1B
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SAFB scaffold attachment factor B
SAP30L SAP30-like
SCAND2P SCAN domain containing 2 pseudogene
SEPHS1 selenophosphate synthetase 1
SFTPB surfactant protein B
SLC12A8 solute carrier family 12, member 8
SPAG4 sperm associated antigen 4
SPN sialophorin
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SRRT serrate, RNA effector molecule
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUGP1 SURP and G patch domain containing 1
TAS2R1 taste receptor, type 2, member 1
TAZ tafazzin
TBX19 T-box 19
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGFBR3 transforming growth factor, beta receptor III
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TIMP2 TIMP metallopeptidase inhibitor 2
TMCC1 transmembrane and coiled-coil domain family 1
TMEM63A transmembrane protein 63A
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRADD TNFRSF1A-associated via death domain
TRAM2 translocation associated membrane protein 2
TSPAN13 tetraspanin 13
TTC38 tetratricopeptide repeat domain 38
YIPF2 Yip1 domain family, member 2
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF277 zinc finger protein 277
ZNF354A zinc finger protein 354A
ZNF493 zinc finger protein 493
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABHD3 abhydrolase domain containing 3
ADAM10 ADAM metallopeptidase domain 10
ANO10 anoctamin 10
ANXA3 annexin A3
ARG1 arginase 1
ARHGAP10 Rho GTPase activating protein 10
ATAD2 ATPase family, AAA domain containing 2
ATG14 autophagy related 14
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C5ORF15 chromosome 5 open reading frame 15
CASD1 CAS1 domain containing 1
CCDC94 coiled-coil domain containing 94
CCL20 chemokine (C-C motif) ligand 20
CD38 CD38 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CLDND1 claudin domain containing 1
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CORO1C coronin, actin binding protein, 1C
CPOX coproporphyrinogen oxidase
CRTAP cartilage associated protein
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DPY19L2P2 DPY19L2 pseudogene 2
DYM dymeclin
ECD ecdysoneless homolog (Drosophila)
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC5 exocyst complex component 5
FAM173A family with sequence similarity 173, member A
GCH1 GTP cyclohydrolase 1
GLTP glycolipid transfer protein
GNL1 guanine nucleotide binding protein-like 1
GOLGA1 golgin A1
GOLGA8B golgin A8 family, member B
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HMGB3P1 high mobility group box 3 pseudogene 1
HP haptoglobin
HRSP12 heat-responsive protein 12
INPP5F inositol polyphosphate-5-phosphatase F
JMJD1C jumonji domain containing 1C
KAT2A K(lysine) acetyltransferase 2A
KDM5C lysine (K)-specific demethylase 5C
KLHL12 kelch-like family member 12
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LMAN1 lectin, mannose-binding, 1
LSP1 lymphocyte-specific protein 1
MANEA mannosidase, endo-alpha
MAP3K2 mitogen-activated protein kinase kinase kinase 2
METTL8 methyltransferase like 8
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MON1B MON1 secretory trafficking family member B
MYL5 myosin, light chain 5, regulatory
MYO5C myosin VC
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NMD3 NMD3 ribosome export adaptor
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PARG poly (ADP-ribose) glycohydrolase
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PRPF39 pre-mRNA processing factor 39
PSAT1 phosphoserine aminotransferase 1
RAB8B RAB8B, member RAS oncogene family
RBM7 RNA binding motif protein 7
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF146 ring finger protein 146
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNFT1 ring finger protein, transmembrane 1
SAMD9 sterile alpha motif domain containing 9
SLC25A40 solute carrier family 25, member 40
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SPATS2 spermatogenesis associated, serine-rich 2
SRBD1 S1 RNA binding domain 1
SRD5A3 steroid 5 alpha-reductase 3
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STX17 syntaxin 17
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TET3 tet methylcytosine dioxygenase 3
TLR1 toll-like receptor 1
TM6SF1 transmembrane 6 superfamily member 1
TMEM230 transmembrane protein 230
TPST1 tyrosylprotein sulfotransferase 1
TTC33 tetratricopeptide repeat domain 33
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZMYM1 zinc finger, MYM-type 1
ZNF223 zinc finger protein 223
ZNF227 zinc finger protein 227
ZNF280D zinc finger protein 280D
ZNF37BP zinc finger protein 37B, pseudogene
ZNF701 zinc finger protein 701
ZW10 zw10 kinetochore protein