pentoxyverine-5610 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the pentoxyverine-5610 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
AIM1L absent in melanoma 1-like
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
C21ORF2 chromosome 21 open reading frame 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCDC64 coiled-coil domain containing 64
CD200 CD200 molecule
CD52 CD52 molecule
CD58 CD58 molecule
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CIITA class II, major histocompatibility complex, transactivator
COL13A1 collagen, type XIII, alpha 1
CTIF CBP80/20-dependent translation initiation factor
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYTH4 cytohesin 4
DCTN1 dynactin 1
DEFA5 defensin, alpha 5, Paneth cell-specific
DEFB126 defensin, beta 126
DENND1C DENN/MADD domain containing 1C
DKFZP434L187 uncharacterized LOC26082
EFCAB6 EF-hand calcium binding domain 6
EPHB1 EPH receptor B1
ERAP1 endoplasmic reticulum aminopeptidase 1
ERCC2 excision repair cross-complementation group 2
FABP3 fatty acid binding protein 3, muscle and heart
FCAR Fc fragment of IgA receptor
FGF13 fibroblast growth factor 13
FGF18 fibroblast growth factor 18
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
GIPR gastric inhibitory polypeptide receptor
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GP2 glycoprotein 2 (zymogen granule membrane)
GPRC5D G protein-coupled receptor, class C, group 5, member D
GRK5 G protein-coupled receptor kinase 5
GRM1 glutamate receptor, metabotropic 1
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KCNIP1 Kv channel interacting protein 1
KCNK2 potassium channel, two pore domain subfamily K, member 2
KIF13A kinesin family member 13A
KIFC3 kinesin family member C3
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAMA4 laminin, alpha 4
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LTBP4 latent transforming growth factor beta binding protein 4
MAPK7 mitogen-activated protein kinase 7
MUC4 mucin 4, cell surface associated
MX2 MX dynamin-like GTPase 2
NCLN nicalin
NEK9 NIMA-related kinase 9
NKX2-1 NK2 homeobox 1
NNAT neuronatin
OTOR otoraplin
PAPPA2 pappalysin 2
PAX3 paired box 3
PDE4A phosphodiesterase 4A, cAMP-specific
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
POMT2 protein-O-mannosyltransferase 2
POPDC3 popeye domain containing 3
POU6F1 POU class 6 homeobox 1
PPP1R17 protein phosphatase 1, regulatory subunit 17
PSAT1 phosphoserine aminotransferase 1
PTCRA pre T-cell antigen receptor alpha
PTPRD protein tyrosine phosphatase, receptor type, D
PYY peptide YY
R3HDM1 R3H domain containing 1
RNF126P1 ring finger protein 126 pseudogene 1
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SAYSD1 SAYSVFN motif domain containing 1
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SFTPB surfactant protein B
SIRT5 sirtuin 5
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMR3A submaxillary gland androgen regulated protein 3A
SOD3 superoxide dismutase 3, extracellular
SPINK5 serine peptidase inhibitor, Kazal type 5
SPON1 spondin 1, extracellular matrix protein
SRSF5 serine/arginine-rich splicing factor 5
TAAR3 trace amine associated receptor 3 (gene/pseudogene)
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TFDP3 transcription factor Dp family, member 3
TGFB2 transforming growth factor, beta 2
TGM2 transglutaminase 2
THEMIS2 thymocyte selection associated family member 2
THTPA thiamine triphosphatase
TRO trophinin
TTPA tocopherol (alpha) transfer protein
TUBBP5 tubulin, beta pseudogene 5
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
WAS Wiskott-Aldrich syndrome
WSCD1 WSC domain containing 1
YY2 YY2 transcription factor
ZEB1 zinc finger E-box binding homeobox 1

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ADAP2 ArfGAP with dual PH domains 2
ADCY6 adenylate cyclase 6
AEN apoptosis enhancing nuclease
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ALPK1 alpha-kinase 1
AMT aminomethyltransferase
ARMCX2 armadillo repeat containing, X-linked 2
ASAP1-IT1 ASAP1 intronic transcript 1
BEX4 brain expressed, X-linked 4
BMP4 bone morphogenetic protein 4
C10ORF88 chromosome 10 open reading frame 88
C1ORF159 chromosome 1 open reading frame 159
C7ORF43 chromosome 7 open reading frame 43
CBX7 chromobox homolog 7
CCNO cyclin O
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CES3 carboxylesterase 3
CLCN2 chloride channel, voltage-sensitive 2
CLDN9 claudin 9
CLGN calmegin
CNR2 cannabinoid receptor 2 (macrophage)
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DGKE diacylglycerol kinase, epsilon 64kDa
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DRD1 dopamine receptor D1
DSPP dentin sialophosphoprotein
EFNA3 ephrin-A3
ERCC6 excision repair cross-complementation group 6
FAM131A family with sequence similarity 131, member A
FAM155A family with sequence similarity 155, member A
FBXO31 F-box protein 31
FFAR2 free fatty acid receptor 2
FGF23 fibroblast growth factor 23
FILIP1L filamin A interacting protein 1-like
FKBP1B FK506 binding protein 1B, 12.6 kDa
GBAS glioblastoma amplified sequence
GMIP GEM interacting protein
GPATCH2L G patch domain containing 2-like
GRPR gastrin-releasing peptide receptor
GSTA4 glutathione S-transferase alpha 4
HHLA3 HERV-H LTR-associating 3
HIST1H2AJ histone cluster 1, H2aj
INCENP inner centromere protein antigens 135/155kDa
ISG15 ISG15 ubiquitin-like modifier
JMJD4 jumonji domain containing 4
LINC00597 long intergenic non-protein coding RNA 597
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC257152 uncharacterized LOC257152
LOXL3 lysyl oxidase-like 3
LRRC20 leucine rich repeat containing 20
MALL mal, T-cell differentiation protein-like
MBIP MAP3K12 binding inhibitory protein 1
MCOLN1 mucolipin 1
MMP9 matrix metallopeptidase 9
MOSPD3 motile sperm domain containing 3
NEK11 NIMA-related kinase 11
NME5 NME/NM23 family member 5
NPIPB3 nuclear pore complex interacting protein family, member B3
NSUN3 NOP2/Sun domain family, member 3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSGIN1 oxidative stress induced growth inhibitor 1
OVOL1 ovo-like zinc finger 1
PGP phosphoglycolate phosphatase
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PRR14L proline rich 14-like
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFXAP regulatory factor X-associated protein
RUNDC3B RUN domain containing 3B
S100A2 S100 calcium binding protein A2
SCN1B sodium channel, voltage gated, type I beta subunit
SCRN3 secernin 3
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMIM14 small integral membrane protein 14
SREBF1 sterol regulatory element binding transcription factor 1
STBD1 starch binding domain 1
STIM1 stromal interaction molecule 1
TBX19 T-box 19
TMEM180 transmembrane protein 180
TMEM254 transmembrane protein 254
UBTD1 ubiquitin domain containing 1
YBX2 Y box binding protein 2
ZBTB33 zinc finger and BTB domain containing 33
ZBTB44 zinc finger and BTB domain containing 44
ZFP37 ZFP37 zinc finger protein
ZNF134 zinc finger protein 134
ZNF205 zinc finger protein 205
ZNF219 zinc finger protein 219
ZNF34 zinc finger protein 34
ZNF480 zinc finger protein 480
ZNF484 zinc finger protein 484
ZNF804A zinc finger protein 804A