| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the pepstatin-4790 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ADORA1 | adenosine A1 receptor |
| ADRB1 | adrenoceptor beta 1 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AIM2 | absent in melanoma 2 |
| ALOX12B | arachidonate 12-lipoxygenase, 12R type |
| AMACR | alpha-methylacyl-CoA racemase |
| AOX1 | aldehyde oxidase 1 |
| B9D1 | B9 protein domain 1 |
| BGN | biglycan |
| BMP6 | bone morphogenetic protein 6 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C2ORF72 | chromosome 2 open reading frame 72 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CALD1 | caldesmon 1 |
| CARD14 | caspase recruitment domain family, member 14 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CASR | calcium-sensing receptor |
| CD6 | CD6 molecule |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CHKB | choline kinase beta |
| CLDN17 | claudin 17 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CNTNAP2 | contactin associated protein-like 2 |
| COL10A1 | collagen, type X, alpha 1 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DCN | decorin |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| EDA | ectodysplasin A |
| EFNA3 | ephrin-A3 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| ESR1 | estrogen receptor 1 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FBXO38 | F-box protein 38 |
| FCMR | Fc fragment of IgM receptor |
| FOXA2 | forkhead box A2 |
| FOXN3 | forkhead box N3 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GIPR | gastric inhibitory polypeptide receptor |
| GPR1 | G protein-coupled receptor 1 |
| HOXB6 | homeobox B6 |
| HPSE2 | heparanase 2 (inactive) |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
| HSPA12A | heat shock 70kDa protein 12A |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IFT27 | intraflagellar transport 27 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IGL | immunoglobulin lambda locus |
| IL1RN | interleukin 1 receptor antagonist |
| INE1 | inactivation escape 1 (non-protein coding) |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 |
| LEFTY2 | left-right determination factor 2 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MCAM | melanoma cell adhesion molecule |
| MED25 | mediator complex subunit 25 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MTCP1 | mature T-cell proliferation 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| PAPPA2 | pappalysin 2 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PNPLA2 | patatin-like phospholipase domain containing 2 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| PTPRA | protein tyrosine phosphatase, receptor type, A |
| PTPRJ | protein tyrosine phosphatase, receptor type, J |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD51B | RAD51 paralog B |
| REC8 | REC8 meiotic recombination protein |
| RGS12 | regulator of G-protein signaling 12 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SIRT5 | sirtuin 5 |
| SIX1 | SIX homeobox 1 |
| SLA | Src-like-adaptor |
| SLCO1B1 | solute carrier organic anion transporter family, member 1B1 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| TBX5 | T-box 5 |
| TGM2 | transglutaminase 2 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TOR4A | torsin family 4, member A |
| TPSAB1 | tryptase alpha/beta 1 |
| TRIM2 | tripartite motif containing 2 |
| TSSK2 | testis-specific serine kinase 2 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF423 | zinc finger protein 423 |
| ZNF532 | zinc finger protein 532 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BBC3 | BCL2 binding component 3 |
| BTD | biotinidase |
| C1ORF27 | chromosome 1 open reading frame 27 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CCNL2 | cyclin L2 |
| CENPC | centromere protein C |
| CISH | cytokine inducible SH2-containing protein |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLK1 | CDC-like kinase 1 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CSRNP2 | cysteine-serine-rich nuclear protein 2 |
| CST6 | cystatin E/M |
| CXADR | coxsackie virus and adenovirus receptor |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DESI1 | desumoylating isopeptidase 1 |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| DNAL4 | dynein, axonemal, light chain 4 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERF | Ets2 repressor factor |
| FAM120C | family with sequence similarity 120C |
| FBXO22 | F-box protein 22 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOXA1 | forkhead box A1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GALK1 | galactokinase 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa |
| GTF2I | general transcription factor IIi |
| HIST1H2AJ | histone cluster 1, H2aj |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL17RA | interleukin 17 receptor A |
| INSIG2 | insulin induced gene 2 |
| INTS9 | integrator complex subunit 9 |
| IRF1 | interferon regulatory factor 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| JRKL | JRK-like |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIFAP3 | kinesin-associated protein 3 |
| LIF | leukemia inhibitory factor |
| LOC642236 | FSHD region gene 1 pseudogene |
| LYRM9 | LYR motif containing 9 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MGC12488 | |
| MITF | microphthalmia-associated transcription factor |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NRTN | neurturin |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| ONECUT2 | one cut homeobox 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PCBP4 | poly(rC) binding protein 4 |
| PLXNA3 | plexin A3 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RHBDD3 | rhomboid domain containing 3 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
| RUNDC3B | RUN domain containing 3B |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIK1 | salt-inducible kinase 1 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNX16 | sorting nexin 16 |
| SPATA7 | spermatogenesis associated 7 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TCTN1 | tectonic family member 1 |
| TDRD12 | tudor domain containing 12 |
| TMEM104 | transmembrane protein 104 |
| TMEM2 | transmembrane protein 2 |
| TMEM230 | transmembrane protein 230 |
| TRAPPC2 | trafficking protein particle complex 2 |
| TRIM25 | tripartite motif containing 25 |
| TSGA10 | testis specific, 10 |
| TSPAN1 | tetraspanin 1 |
| TSPYL2 | TSPY-like 2 |
| USP18 | ubiquitin specific peptidase 18 |
| WDR25 | WD repeat domain 25 |
| ZNF324 | zinc finger protein 324 |
| ZNF350 | zinc finger protein 350 |
| ZNF430 | zinc finger protein 430 |
| ZNF586 | zinc finger protein 586 |
| ZNF654 | zinc finger protein 654 |
| ZNF778 | zinc finger protein 778 |
| ZNF83 | zinc finger protein 83 |
