peptic ulcer disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

259 genes co-occuring with the disease peptic ulcer disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 3.63221
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 3.63221
GAST gastrin 3.44471
HRH2 histamine receptor H2 2.71224
SST somatostatin 1.80923
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.5943
INS insulin 1.46276
CCK cholecystokinin 1.37556
OCM2 oncomodulin 2 1.36204
PPY pancreatic polypeptide 1.34853
OCM oncomodulin 1.34068
PGC progastricsin (pepsinogen C) 1.32716
GRP gastrin-releasing peptide 1.32629
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 1.2595
CXCL8 chemokine (C-X-C motif) ligand 8 1.2508
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.22258
DNAH8 dynein, axonemal, heavy chain 8 1.22085
IL1B interleukin 1, beta 1.12825
MLN motilin 1.06942
CD79A CD79a molecule, immunoglobulin-associated alpha 1.05934
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.05261
GCG glucagon 1.01891
NTS neurotensin 0.996127
POMP proteasome maturation protein 0.980952
IL1RN interleukin 1 receptor antagonist 0.97002
LCT lactase 0.947852
ALB albumin 0.894589
PGA3 pepsinogen 3, group I (pepsinogen A) 0.857724
PGA4 pepsinogen 4, group I (pepsinogen A) 0.857724
SOD2 superoxide dismutase 2, mitochondrial 0.821257
CAT catalase 0.803616
GIF gastric intrinsic factor (vitamin B synthesis) 0.798692
CALCA calcitonin-related polypeptide alpha 0.797872
POMC proopiomelanocortin 0.795821
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 0.778204
MPO myeloperoxidase 0.760639
ALPPL2 alkaline phosphatase, placental-like 2 0.749644
ALPP alkaline phosphatase, placental 0.749237
ALPL alkaline phosphatase, liver/bone/kidney 0.74883
F2 coagulation factor II (thrombin) 0.730976
EHF ets homologous factor 0.724502
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.715215
MEN1 multiple endocrine neoplasia I 0.712796
GHRL ghrelin/obestatin prepropeptide 0.71078
ADGRL1 adhesion G protein-coupled receptor L1 0.71078
GIP gastric inhibitory polypeptide 0.677105
TFF2 trefoil factor 2 0.67113
DCLK3 doublecortin-like kinase 3 0.65763
PTH parathyroid hormone 0.637889
TNF tumor necrosis factor 0.615921
SCG5 secretogranin V 0.612792
HNMT histamine N-methyltransferase 0.605762
CD4 CD4 molecule 0.571495
PTPRB protein tyrosine phosphatase, receptor type, B 0.560227
CCKBR cholecystokinin B receptor 0.559839
TRH thyrotropin-releasing hormone 0.547032
MUC6 mucin 6, oligomeric mucus/gel-forming 0.545868
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.517265
CBS cystathionine-beta-synthase 0.516494
LYZ lysozyme 0.504207
ASMT acetylserotonin O-methyltransferase 0.494266
PCNA proliferating cell nuclear antigen 0.49274
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.491978
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.486646
AMICA1 adhesion molecule, interacts with CXADR antigen 1 0.485505
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.479047
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.470332
SPAG6 sperm associated antigen 6 0.470332
FGF2 fibroblast growth factor 2 (basic) 0.467684
TOX thymocyte selection-associated high mobility group box 0.46655
CCKAR cholecystokinin A receptor 0.457109
RER1 retention in endoplasmic reticulum sorting receptor 1 0.456732
ESPN espin 0.454093
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 0.449571
FLNA filamin A, alpha 0.446182
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.437906
MGAM maltase-glucoamylase 0.436026
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.431519
AANAT aralkylamine N-acetyltransferase 0.426265
TES testin LIM domain protein 0.411657
MGP matrix Gla protein 0.407545
OAF OAF homolog (Drosophila) 0.404557
HIST2H2AC histone cluster 2, H2ac 0.400826
HIST2H2AA4 histone cluster 2, H2aa4 0.400453
HIST2H2AA3 histone cluster 2, H2aa3 0.400453
HDC histidine decarboxylase 0.397471
NOS2 nitric oxide synthase 2, inducible 0.388538
TLR4 toll-like receptor 4 0.385193
CISD2 CDGSH iron sulfur domain 2 0.384451
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.380368
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.377773
ODC1 ornithine decarboxylase 1 0.372958
PYY peptide YY 0.372217
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.369997
TREH trehalase (brush-border membrane glycoprotein) 0.36704
IFT122 intraflagellar transport 122 0.361502
FEZF1 FEZ family zinc finger 1 0.357814
NPS neuropeptide S 0.355235
FEZF2 FEZ family zinc finger 2 0.347144
L3MBTL3 l(3)mbt-like 3 (Drosophila) 0.344574
ADM2 adrenomedullin 2 0.335778
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.334315
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.326281
APLF aprataxin and PNKP like factor 0.323002
MOB1A MOB kinase activator 1A 0.317909
NOD1 nucleotide-binding oligomerization domain containing 1 0.315729
GRHL1 grainyhead-like 1 (Drosophila) 0.313552
PLG plasminogen 0.307395
FGD5 FYVE, RhoGEF and PH domain containing 5 0.306672
IGLV2-8 immunoglobulin lambda variable 2-8 0.30631
CDX2 caudal type homeobox 2 0.305587
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.300533
SELPLG selectin P ligand 0.299092
MUSTN1 musculoskeletal, embryonic nuclear protein 1 0.299092
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.298731
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.296571
PRL prolactin 0.290103
PRSS21 protease, serine, 21 (testisin) 0.288668
WAPAL wings apart-like homolog (Drosophila) 0.287952
CRH corticotropin releasing hormone 0.284013
CRP C-reactive protein, pentraxin-related 0.271174
ACVRL1 activin A receptor type II-like 1 0.269753
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.268687
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.257711
VGF VGF nerve growth factor inducible 0.257711
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 0.256652
A4GNT alpha-1,4-N-acetylglucosaminyltransferase 0.254536
CCL3 chemokine (C-C motif) ligand 3 0.245747
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 0.235616
HSPA1L heat shock 70kDa protein 1-like 0.23353
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.233183
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.232836
BCHE butyrylcholinesterase 0.231448
CHGA chromogranin A 0.22937
TLR2 toll-like receptor 2 0.22937
TFF1 trefoil factor 1 0.228333
GSR glutathione reductase 0.225917
FBF1 Fas (TNFRSF6) binding factor 1 0.22454
ZFYVE9 zinc finger, FYVE domain containing 9 0.224196
PLA2G1B phospholipase A2, group IB (pancreas) 0.223509
ACE angiotensin I converting enzyme 0.221108
LTF lactotransferrin 0.219057
SLBP stem-loop binding protein 0.218374
EGR1 early growth response 1 0.217693
PRRC2A proline-rich coiled-coil 2A 0.212608
GPX5 glutathione peroxidase 5 0.210253
CYGB cytoglobin 0.209583
GPX4 glutathione peroxidase 4 0.207578
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.205585
ARG2 arginase 2 0.203604
PSCA prostate stem cell antigen 0.202946
TET3 tet methylcytosine dioxygenase 3 0.20229
SOCS2 suppressor of cytokine signaling 2 0.201962
VIP vasoactive intestinal peptide 0.199356
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.199033
TMEM51 transmembrane protein 51 0.199033
F3 coagulation factor III (thromboplastin, tissue factor) 0.198709
VWF von Willebrand factor 0.196779
CTSE cathepsin E 0.194548
GPX1 glutathione peroxidase 1 0.194232
TP53 tumor protein p53 0.194232
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 0.192344
CLDN3 claudin 3 0.190786
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.187113
MUC2 mucin 2, oligomeric mucus/gel-forming 0.18591
SMOX spermine oxidase 0.183541
TF transferrin 0.182957
IL6 interleukin 6 0.182957
NADK NAD kinase 0.182666
LMO7 LIM domain 7 0.179802
PTPN7 protein tyrosine phosphatase, non-receptor type 7 0.173314
SLC26A9 solute carrier family 26 (anion exchanger), member 9 0.171785
LTA lymphotoxin alpha 0.171535
GSTA3 glutathione S-transferase alpha 3 0.170789
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.170299
GSTA2 glutathione S-transferase alpha 2 0.170054
GSTA4 glutathione S-transferase alpha 4 0.16933
EPHA4 EPH receptor A4 0.165874
GSTA1 glutathione S-transferase alpha 1 0.165655
TAC1 tachykinin, precursor 1 0.164359
KIAA0101 KIAA0101 0.162707
EBF2 early B-cell factor 2 0.162306
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.161523
GH1 growth hormone 1 0.160761
PTPRA protein tyrosine phosphatase, receptor type, A 0.159302
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.159124
SCAI suppressor of cancer cell invasion 0.1394
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 0.138639
AMELY amelogenin, Y-linked 0.13752
CHL1 cell adhesion molecule L1-like 0.137379
AMELX amelogenin, X-linked 0.136883
CD34 CD34 molecule 0.136827
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.136514
ENG endoglin 0.134823
CLDN1 claudin 1 0.134676
CLDN7 claudin 7 0.134288
THAP3 THAP domain containing, apoptosis associated protein 3 0.133504
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene 0.133492
CNGB3 cyclic nucleotide gated channel beta 3 0.133186
EZR ezrin 0.132106
CXCR1 chemokine (C-X-C motif) receptor 1 0.131853
CLDN14 claudin 14 0.131752
MRS2 MRS2 magnesium transporter 0.131666
RSPO1 R-spondin 1 0.131445
HGFAC HGF activator 0.131357
DNASE2 deoxyribonuclease II, lysosomal 0.131114
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.131022
IFNE interferon, epsilon 0.130661
FYN FYN proto-oncogene, Src family tyrosine kinase 0.130087
ADGRV1 adhesion G protein-coupled receptor V1 0.129501
THEM4 thioesterase superfamily member 4 0.12943
DKK4 dickkopf WNT signaling pathway inhibitor 4 0.12894
PLEKHN1 pleckstrin homology domain containing, family N member 1 0.128639
GPBAR1 G protein-coupled bile acid receptor 1 0.128234
DVL3 dishevelled segment polarity protein 3 0.127321
NBPF1 neuroblastoma breakpoint family, member 1 0.127152
OCA2 oculocutaneous albinism II 0.12652
MYO9B myosin IXB 0.12652
RPL13A ribosomal protein L13a 0.126475
PRAMEF10 PRAME family member 10 0.125241
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.124921
IL18RAP interleukin 18 receptor accessory protein 0.124544
MIXL1 Mix paired-like homeobox 0.123923
SCARF1 scavenger receptor class F, member 1 0.123495
GH2 growth hormone 2 0.123414
FUCA2 fucosidase, alpha-L- 2, plasma 0.123359
OCLN occludin 0.123029
F13A1 coagulation factor XIII, A1 polypeptide 0.122608
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 0.122464
MLNR motilin receptor 0.122145
WNT3 wingless-type MMTV integration site family, member 3 0.122087
POU2F3 POU class 2 homeobox 3 0.121851
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 0.121851
APITD1 apoptosis-inducing, TAF9-like domain 1 0.121731
FBXL15 F-box and leucine-rich repeat protein 15 0.121341
CA6 carbonic anhydrase VI 0.120908
AMY2A amylase, alpha 2A (pancreatic) 0.120659
PTCH1 patched 1 0.12021
ASRGL1 asparaginase like 1 0.119919
RHOD ras homolog family member D 0.119753
SMAD4 SMAD family member 4 0.11972
DARS aspartyl-tRNA synthetase 0.119621
MARS methionyl-tRNA synthetase 0.118844
ALOX15 arachidonate 15-lipoxygenase 0.118322
KRT7 keratin 7, type II 0.11818
IFI44L interferon-induced protein 44-like 0.117753
VIPR2 vasoactive intestinal peptide receptor 2 0.116188
STYK1 serine/threonine/tyrosine kinase 1 0.1158
PZP pregnancy-zone protein 0.115448
CCL26 chemokine (C-C motif) ligand 26 0.115047
CDX1 caudal type homeobox 1 0.113138
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 0.11275
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.11275
TSLP thymic stromal lymphopoietin 0.112618
AGR2 anterior gradient 2 0.111506
SOD3 superoxide dismutase 3, extracellular 0.111054
XDH xanthine dehydrogenase 0.110449
CD109 CD109 molecule 0.109455
GSTP1 glutathione S-transferase pi 1 0.109407