peptidase inhibitor activity Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
Description Stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds. (Gene Ontology, GO_0030414)
External Link http://amigo.geneontology.org/amigo/term/GO:0030414
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Genes

41 genes performing the peptidase inhibitor activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
A2M alpha-2-macroglobulin
A2ML1 alpha-2-macroglobulin-like 1
AHSG alpha-2-HS-glycoprotein
CST3 cystatin C
CST7 cystatin F (leukocystatin)
CSTB cystatin B (stefin B)
ERC2 ELKS/RAB6-interacting/CAST family member 2
GBP2 guanylate binding protein 2, interferon-inducible
GBP5 guanylate binding protein 5
GPC3 glypican 3
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
LPA lipoprotein, Lp(a)
OPRPN opiorphin prepropeptide
PARK7 parkinson protein 7
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PI3 peptidase inhibitor 3, skin-derived
PROS1 protein S (alpha)
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PZP pregnancy-zone protein
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RENBP renin binding protein
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SGPP2 sphingosine-1-phosphate phosphatase 2
SIMC1 SUMO-interacting motifs containing 1
SLPI secretory leukocyte peptidase inhibitor
SMR3A submaxillary gland androgen regulated protein 3A
SMR3B submaxillary gland androgen regulated protein 3B
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPINT2 serine peptidase inhibitor, Kunitz type, 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
WFDC2 WAP four-disulfide core domain 2