| Dataset | GO Biological Process Annotations 2025 |
| Category | structural or functional annotations |
| Type | biological process |
| Description | The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions. (Gene Ontology, GO_0001519) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0001519 |
| Similar Terms | |
| Downloads & Tools |
2 genes participating in the peptide amidation biological process from the curated GO Biological Process Annotations 2025 dataset.
