pergolide-7031 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the pergolide-7031 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD5 abhydrolase domain containing 5
ADA adenosine deaminase
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ALS2CL ALS2 C-terminal like
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATXN2L ataxin 2-like
AXIN1 axin 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BBS9 Bardet-Biedl syndrome 9
C14ORF93 chromosome 14 open reading frame 93
CARTPT CART prepropeptide
CC2D1A coiled-coil and C2 domain containing 1A
CCDC85B coiled-coil domain containing 85B
CEP131 centrosomal protein 131kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CHD3 chromodomain helicase DNA binding protein 3
CLEC11A C-type lectin domain family 11, member A
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DIO2 deiodinase, iodothyronine, type II
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
EDNRA endothelin receptor type A
FAM178A family with sequence similarity 178, member A
FAM53B family with sequence similarity 53, member B
FAM63A family with sequence similarity 63, member A
FBXO42 F-box protein 42
FZD7 frizzled class receptor 7
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPR153 G protein-coupled receptor 153
GRB10 growth factor receptor-bound protein 10
HOXC10 homeobox C10
HOXC8 homeobox C8
HSF1 heat shock transcription factor 1
IDI2-AS1 IDI2 antisense RNA 1
IGHMBP2 immunoglobulin mu binding protein 2
INTS7 integrator complex subunit 7
ITPKB inositol-trisphosphate 3-kinase B
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KLF11 Kruppel-like factor 11
LIG3 ligase III, DNA, ATP-dependent
LIN7A lin-7 homolog A (C. elegans)
LOC100272216 uncharacterized LOC100272216
LOC730101 uncharacterized LOC730101
LZTR1 leucine-zipper-like transcription regulator 1
MAP4 microtubule-associated protein 4
MAST4 microtubule associated serine/threonine kinase family member 4
METTL7A methyltransferase like 7A
MFSD11 major facilitator superfamily domain containing 11
MGC12488
N4BP2L2 NEDD4 binding protein 2-like 2
NDE1 nudE neurodevelopment protein 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NME5 NME/NM23 family member 5
NRTN neurturin
ONECUT2 one cut homeobox 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSGIN1 oxidative stress induced growth inhibitor 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM7 PDZ and LIM domain 7 (enigma)
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
POU4F1 POU class 4 homeobox 1
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTK6 protein tyrosine kinase 6
PTPRA protein tyrosine phosphatase, receptor type, A
PTPRF protein tyrosine phosphatase, receptor type, F
RABGAP1 RAB GTPase activating protein 1
RALGDS ral guanine nucleotide dissociation stimulator
RRBP1 ribosome binding protein 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCARB1 scavenger receptor class B, member 1
SCLY selenocysteine lyase
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SETD1A SET domain containing 1A
SH2B3 SH2B adaptor protein 3
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
STK17B serine/threonine kinase 17b
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TSNAXIP1 translin-associated factor X interacting protein 1
VAV2 vav 2 guanine nucleotide exchange factor
VDAC3 voltage-dependent anion channel 3
WDR61 WD repeat domain 61
WSB1 WD repeat and SOCS box containing 1
ZBTB40 zinc finger and BTB domain containing 40
ZNF134 zinc finger protein 134
ZNF407 zinc finger protein 407
ZNF492 zinc finger protein 492
ZNF571 zinc finger protein 571

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANXA1 annexin A1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCORL1 BCL6 corepressor-like 1
BMP4 bone morphogenetic protein 4
BTBD2 BTB (POZ) domain containing 2
C16ORF59 chromosome 16 open reading frame 59
C21ORF91 chromosome 21 open reading frame 91
C9ORF40 chromosome 9 open reading frame 40
CA11 carbonic anhydrase XI
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCDC85C coiled-coil domain containing 85C
CCNE1 cyclin E1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPT centromere protein T
CGREF1 cell growth regulator with EF-hand domain 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CISH cytokine inducible SH2-containing protein
CLSPN claspin
COL9A2 collagen, type IX, alpha 2
CUEDC1 CUE domain containing 1
CXORF56 chromosome X open reading frame 56
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DUSP5 dual specificity phosphatase 5
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
FLT4 fms-related tyrosine kinase 4
FSD1 fibronectin type III and SPRY domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
FZD4 frizzled class receptor 4
GALK1 galactokinase 1
GAMT guanidinoacetate N-methyltransferase
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IL15RA interleukin 15 receptor, alpha
IMPACT impact RWD domain protein
IRF1 interferon regulatory factor 1
KIZ kizuna centrosomal protein
KLHL26 kelch-like family member 26
LIN7B lin-7 homolog B (C. elegans)
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC20 leucine rich repeat containing 20
LY6D lymphocyte antigen 6 complex, locus D
LYPD1 LY6/PLAUR domain containing 1
LZTFL1 leucine zipper transcription factor-like 1
MBTD1 mbt domain containing 1
MMP9 matrix metallopeptidase 9
MYL5 myosin, light chain 5, regulatory
NAV2 neuron navigator 2
NHEJ1 nonhomologous end-joining factor 1
OLFML3 olfactomedin-like 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCDHB3 protocadherin beta 3
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLD3 phospholipase D family, member 3
POLL polymerase (DNA directed), lambda
PPT2 palmitoyl-protein thioesterase 2
PRICKLE3 prickle homolog 3 (Drosophila)
PROCR protein C receptor, endothelial
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RAB33B RAB33B, member RAS oncogene family
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RECQL4 RecQ protein-like 4
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SHPK sedoheptulokinase
SIRT2 sirtuin 2
SLC12A8 solute carrier family 12, member 8
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMA4 glucuronidase, beta pseudogene
SRBD1 S1 RNA binding domain 1
SSBP3 single stranded DNA binding protein 3
SYBU syntabulin (syntaxin-interacting)
TIGD6 tigger transposable element derived 6
TMEM104 transmembrane protein 104
TMEM2 transmembrane protein 2
TMEM212 transmembrane protein 212
TPCN1 two pore segment channel 1
TRAPPC13 trafficking protein particle complex 13
TRIM5 tripartite motif containing 5
TTLL1 tubulin tyrosine ligase-like family member 1
VEGFC vascular endothelial growth factor C
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR19 WD repeat domain 19
WDR4 WD repeat domain 4
YEATS4 YEATS domain containing 4
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF211 zinc finger protein 211
ZNF254 zinc finger protein 254
ZNF273 zinc finger protein 273
ZNF33B zinc finger protein 33B
ZNF35 zinc finger protein 35
ZNF586 zinc finger protein 586