| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the perhexiline-2410 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BCL3 | B-cell CLL/lymphoma 3 |
| BTG2 | BTG family, member 2 |
| CCDC186 | coiled-coil domain containing 186 |
| CCNG2 | cyclin G2 |
| CD83 | CD83 molecule |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| COQ6 | coenzyme Q6 monooxygenase |
| CSNK1E | casein kinase 1, epsilon |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DCN | decorin |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DHCR7 | 7-dehydrocholesterol reductase |
| EMP1 | epithelial membrane protein 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FLJ11292 | |
| FOXO1 | forkhead box O1 |
| FOXO4 | forkhead box O4 |
| FTH1 | ferritin, heavy polypeptide 1 |
| GOLGA2 | golgin A2 |
| GPNMB | glycoprotein (transmembrane) nmb |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H2BH | histone cluster 1, H2bh |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXA1 | homeobox A1 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ICK | intestinal cell (MAK-like) kinase |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL22 | interleukin 22 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIAA1109 | KIAA1109 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| KYNU | kynureninase |
| LAMA4 | laminin, alpha 4 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LPIN1 | lipin 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| LY96 | lymphocyte antigen 96 |
| MCOLN1 | mucolipin 1 |
| MKL2 | MKL/myocardin-like 2 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1M | metallothionein 1M |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MVK | mevalonate kinase |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NEBL | nebulette |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PGAP3 | post-GPI attachment to proteins 3 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLSCR1 | phospholipid scramblase 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RGS1 | regulator of G-protein signaling 1 |
| RUNX1 | runt-related transcription factor 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPP1 | secreted phosphoprotein 1 |
| SQSTM1 | sequestosome 1 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TRIM3 | tripartite motif containing 3 |
| TSC22D4 | TSC22 domain family, member 4 |
| VCX2 | variable charge, X-linked 2 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZNF500 | zinc finger protein 500 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ACP2 | acid phosphatase 2, lysosomal |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| ADM | adrenomedullin |
| AEN | apoptosis enhancing nuclease |
| ALS2CL | ALS2 C-terminal like |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ASPN | asporin |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| C12ORF43 | chromosome 12 open reading frame 43 |
| C3 | complement component 3 |
| CBR1 | carbonyl reductase 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CCDC86 | coiled-coil domain containing 86 |
| CD320 | CD320 molecule |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CFD | complement factor D (adipsin) |
| CHMP6 | charged multivesicular body protein 6 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| COA4 | cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) |
| COLEC10 | collectin sub-family member 10 (C-type lectin) |
| CTSG | cathepsin G |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| DBR1 | debranching RNA lariats 1 |
| DDN | dendrin |
| DEPDC5 | DEP domain containing 5 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| E4F1 | E4F transcription factor 1 |
| FAM46A | family with sequence similarity 46, member A |
| FAM50B | family with sequence similarity 50, member B |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FCHO1 | FCH domain only 1 |
| FGL1 | fibrinogen-like 1 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GRIP2 | glutamate receptor interacting protein 2 |
| HAMP | hepcidin antimicrobial peptide |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IPO8 | importin 8 |
| KLHDC4 | kelch domain containing 4 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MARCKSL1 | MARCKS-like 1 |
| MED22 | mediator complex subunit 22 |
| METRN | meteorin, glial cell differentiation regulator |
| METTL16 | methyltransferase like 16 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MRPL16 | mitochondrial ribosomal protein L16 |
| MTA2 | metastasis associated 1 family, member 2 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NAT10 | N-acetyltransferase 10 (GCN5-related) |
| NCS1 | neuronal calcium sensor 1 |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PDZD7 | PDZ domain containing 7 |
| PLS1 | plastin 1 |
| PMPCA | peptidase (mitochondrial processing) alpha |
| PODXL2 | podocalyxin-like 2 |
| POM121 | POM121 transmembrane nucleoporin |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PRDX4 | peroxiredoxin 4 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
| PRTN3 | proteinase 3 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RBM42 | RNA binding motif protein 42 |
| RCL1 | RNA terminal phosphate cyclase-like 1 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF122 | ring finger protein 122 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SCAI | suppressor of cancer cell invasion |
| SCRIB | scribbled planar cell polarity protein |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SH2D4A | SH2 domain containing 4A |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
| TFB2M | transcription factor B2, mitochondrial |
| TIMM10 | translocase of inner mitochondrial membrane 10 homolog (yeast) |
| TMEM246 | transmembrane protein 246 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTPAL | tocopherol (alpha) transfer protein-like |
| UNC13B | unc-13 homolog B (C. elegans) |
| UPK3A | uroplakin 3A |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| USB1 | U6 snRNA biogenesis 1 |
| VSIG4 | V-set and immunoglobulin domain containing 4 |
| YY2 | YY2 transcription factor |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF747 | zinc finger protein 747 |
| ZNF816 | zinc finger protein 816 |
