| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the perhexiline-7441 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ATF3 | activating transcription factor 3 |
| BBS9 | Bardet-Biedl syndrome 9 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHKB | choline kinase beta |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GOLGA2 | golgin A2 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HBP1 | HMG-box transcription factor 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H2BO | histone cluster 1, H2bo |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL4R | interleukin 4 receptor |
| INSIG1 | insulin induced gene 1 |
| IRF1 | interferon regulatory factor 1 |
| IRS2 | insulin receptor substrate 2 |
| JAKMIP2 | janus kinase and microtubule interacting protein 2 |
| JUN | jun proto-oncogene |
| KIF3C | kinesin family member 3C |
| KLF10 | Kruppel-like factor 10 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LDLR | low density lipoprotein receptor |
| LPIN1 | lipin 1 |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MSMO1 | methylsterol monooxygenase 1 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MZF1 | myeloid zinc finger 1 |
| N4BP3 | NEDD4 binding protein 3 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NDE1 | nudE neurodevelopment protein 1 |
| NDRG1 | N-myc downstream regulated 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEBL | nebulette |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NF1 | neurofibromin 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SH2D3A | SH2 domain containing 3A |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SMAD3 | SMAD family member 3 |
| SMIM14 | small integral membrane protein 14 |
| SQLE | squalene epoxidase |
| STK17B | serine/threonine kinase 17b |
| SYNGR1 | synaptogyrin 1 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIM2 | tripartite motif containing 2 |
| TUBG2 | tubulin, gamma 2 |
| USP48 | ubiquitin specific peptidase 48 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZNF165 | zinc finger protein 165 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARL15 | ADP-ribosylation factor-like 15 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| CCND3 | cyclin D3 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CHMP6 | charged multivesicular body protein 6 |
| CLSPN | claspin |
| CPTP | ceramide-1-phosphate transfer protein |
| CTPS1 | CTP synthase 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNAJC11 | DnaJ (Hsp40) homolog, subfamily C, member 11 |
| DTWD1 | DTW domain containing 1 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| ERCC3 | excision repair cross-complementation group 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ERO1L | ERO1-like (S. cerevisiae) |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FAM63A | family with sequence similarity 63, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FASTKD1 | FAST kinase domains 1 |
| FCHO1 | FCH domain only 1 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GAR1 | GAR1 ribonucleoprotein |
| GHR | growth hormone receptor |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GOLGA8B | golgin A8 family, member B |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| H2AFY2 | H2A histone family, member Y2 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| IMPACT | impact RWD domain protein |
| INTS9 | integrator complex subunit 9 |
| IP6K1 | inositol hexakisphosphate kinase 1 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KIF5C | kinesin family member 5C |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LMNB2 | lamin B2 |
| LOC100287590 | uncharacterized LOC100287590 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MYO9A | myosin IXA |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) |
| NAT10 | N-acetyltransferase 10 (GCN5-related) |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| OGFRL1 | opioid growth factor receptor-like 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PGP | phosphoglycolate phosphatase |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
| PLD3 | phospholipase D family, member 3 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPIF | peptidylprolyl isomerase F |
| PRR15L | proline rich 15-like |
| PTCD1 | pentatricopeptide repeat domain 1 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF123 | ring finger protein 123 |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRP1 | ribosomal RNA processing 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SHPK | sedoheptulokinase |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SLC46A3 | solute carrier family 46, member 3 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| TET3 | tet methylcytosine dioxygenase 3 |
| TEX30 | testis expressed 30 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TIPIN | TIMELESS interacting protein |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TTC4 | tetratricopeptide repeat domain 4 |
| TUBA3C | tubulin, alpha 3c |
| TUBA4A | tubulin, alpha 4a |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| WDR43 | WD repeat domain 43 |
| WDR47 | WD repeat domain 47 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF286A | zinc finger protein 286A |
| ZW10 | zw10 kinetochore protein |
