pericentric heterochromatin Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description Heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3. (Gene Ontology, GO_0005721)
External Link http://amigo.geneontology.org/amigo/term/GO:0005721
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Genes

22 proteins localized to the pericentric heterochromatin cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
ATRX alpha thalassemia/mental retardation syndrome X-linked
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BAZ1B bromodomain adjacent to zinc finger domain, 1B
CBX1 chromobox homolog 1
CBX3 chromobox homolog 3
CBX5 chromobox homolog 5
CENPC centromere protein C
CHRAC1 chromatin accessibility complex 1
FLYWCH1 FLYWCH-type zinc finger 1
HELLS helicase, lymphoid-specific
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INCENP inner centromere protein antigens 135/155kDa
KMT5C lysine methyltransferase 5C
LRWD1 leucine-rich repeats and WD repeat domain containing 1
MACROH2A1 macroH2A.1 histone
NCAPD3 non-SMC condensin II complex, subunit D3
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
SIRT6 sirtuin 6
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SNAI1 snail family zinc finger 1
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
ZNF618 zinc finger protein 618