periodontitis Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology) (Experimental Factor Ontology, EFO_0000649)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:824
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Genes

51 genes associated with the disease periodontitis in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
GLT6D1 glycosyltransferase 6 domain containing 1 1.4479
ADGRE1 adhesion G protein-coupled receptor E1 1.21019
NKAIN2 Na+/K+ transporting ATPase interacting 2 1.21019
BIRC5 baculoviral IAP repeat containing 5 1.19386
TENM2 teneurin transmembrane protein 2 1.19386
WDR73 WD repeat domain 73 1.14463
TIMP2 TIMP metallopeptidase inhibitor 2 1.14463
THSD4 thrombospondin, type I, domain containing 4 1.14463
LBP lipopolysaccharide binding protein 1.14463
FBXO38 F-box protein 38 1.14463
OTOF otoferlin 1.14463
IGF2R insulin-like growth factor 2 receptor 1.14463
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 1.11948
CSMD1 CUB and Sushi multiple domains 1 1.10764
ACTN2 actinin, alpha 2 1.10764
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase 1.10764
ERC2 ELKS/RAB6-interacting/CAST family member 2 1.07599
ST20 suppressor of tumorigenicity 20 1.07599
GRID1 glutamate receptor, ionotropic, delta 1 1.07599
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 1.07599
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 1.07599
ACTN1 actinin, alpha 1 1.07599
ETNK2 ethanolamine kinase 2 1.04846
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 1.04846
SCN2A sodium channel, voltage gated, type II alpha subunit 1.04846
LRP1B low density lipoprotein receptor-related protein 1B 1.04846
ZNF579 zinc finger protein 579 1.04846
TGIF1 TGFB-induced factor homeobox 1 1.04846
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 1.04846
CAMTA1 calmodulin binding transcription activator 1 1.04846
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 1.04846
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 1.04846
CCDC13 coiled-coil domain containing 13 1.02476
NLGN1 neuroligin 1 1.02476
KDM4B lysine (K)-specific demethylase 4B 1.02476
FAM126A family with sequence similarity 126, member A 1.02476
NPAP1 nuclear pore associated protein 1 1.02476
GRIK1 glutamate receptor, ionotropic, kainate 1 1.00407
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.00407
NKAIN3 Na+/K+ transporting ATPase interacting 3 1.00407
GPN1 GPN-loop GTPase 1 0.986376
IQSEC1 IQ motif and Sec7 domain 1 0.982826
FOXA1 forkhead box A1 0.982668
HLA-DOA major histocompatibility complex, class II, DO alpha 0.971169
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 0.971169
PTPRT protein tyrosine phosphatase, receptor type, T 0.971169
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.971169
FAM135B family with sequence similarity 135, member B 0.971169
ITGA8 integrin, alpha 8 0.971169
CDH13 cadherin 13 0.971169
STARD8 StAR-related lipid transfer (START) domain containing 8 0.962871