periodontitis Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology) (Experimental Factor Ontology, EFO_0000649)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0000704
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Genes

44 genes associated with the periodontitis phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
GLT6D1 glycosyltransferase 6 domain containing 1 1.27347
ADGRE1 adhesion G protein-coupled receptor E1 1.05869
NKAIN2 Na+/K+ transporting ATPase interacting 2 1.05869
BIRC5 baculoviral IAP repeat containing 5 1.04365
LBP lipopolysaccharide binding protein 1.00059
WDR73 WD repeat domain 73 1.00059
TIMP2 TIMP metallopeptidase inhibitor 2 1.00059
THSD4 thrombospondin, type I, domain containing 4 1.00059
IGF2R insulin-like growth factor 2 receptor 1.00059
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.979167
ACTN2 actinin, alpha 2 0.969142
CSMD1 CUB and Sushi multiple domains 1 0.969142
ST20 suppressor of tumorigenicity 20 0.942765
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.942765
ACTN1 actinin, alpha 1 0.942765
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.942765
SCN2A sodium channel, voltage gated, type II alpha subunit 0.919744
LRP1B low density lipoprotein receptor-related protein 1B 0.919744
ZNF579 zinc finger protein 579 0.919744
ETNK2 ethanolamine kinase 2 0.919744
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 0.919744
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.919744
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.919744
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 0.919744
TGIF1 TGFB-induced factor homeobox 1 0.919744
CCDC13 coiled-coil domain containing 13 0.899912
NLGN1 neuroligin 1 0.899912
NPAP1 nuclear pore associated protein 1 0.899912
FAM126A family with sequence similarity 126, member A 0.899912
KDM4B lysine (K)-specific demethylase 4B 0.899912
NKAIN3 Na+/K+ transporting ATPase interacting 3 0.882984
GRIK1 glutamate receptor, ionotropic, kainate 1 0.882984
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.882984
GPN1 GPN-loop GTPase 1 0.868241
IQSEC1 IQ motif and Sec7 domain 1 0.865306
FOXA1 forkhead box A1 0.865175
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.855449
ITGA8 integrin, alpha 8 0.855449
PTPRT protein tyrosine phosphatase, receptor type, T 0.855449
CDH13 cadherin 13 0.855449
FAM135B family with sequence similarity 135, member B 0.855449
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 0.855449
HLA-DOA major histocompatibility complex, class II, DO alpha 0.855449
STARD8 StAR-related lipid transfer (START) domain containing 8 0.848219