periodontitis Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology) (Experimental Factor Ontology, EFO_0000649)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0000704
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Genes

14 genes associated with the periodontitis phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
AP3B1 adaptor-related protein complex 3, beta 1 subunit
COL3A1 collagen, type III, alpha 1
CTSC cathepsin C
EDAR ectodysplasin A receptor
EDARADD EDAR-associated death domain
ELANE elastase, neutrophil expressed
FERMT1 fermitin family member 1
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
LYST lysosomal trafficking regulator
NOTCH2 notch 2
OCRL oculocerebrorenal syndrome of Lowe
PLG plasminogen
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase