peritonitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A gastrointestinal system disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. Peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. The symptoms include abdominal pain and tenderness, fever, fluid in the abdomen, nausea, vomiting and low urine output. (Human Disease Ontology, DOID_8283)
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Genes

317 genes co-occuring with the disease peritonitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ALB albumin 2.17759
ISPD isoprenoid synthase domain containing 2.00378
TNF tumor necrosis factor 1.74824
IL6 interleukin 6 1.58359
IL1B interleukin 1, beta 1.54893
CRP C-reactive protein, pentraxin-related 1.51765
USF2 upstream transcription factor 2, c-fos interacting 1.42849
MEFV Mediterranean fever 1.37207
MPO myeloperoxidase 1.29746
F2 coagulation factor II (thrombin) 1.22475
C5AR1 complement component 5a receptor 1 1.20353
CCL2 chemokine (C-C motif) ligand 2 1.19186
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.14815
ICAM1 intercellular adhesion molecule 1 1.12741
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.11982
CXCL8 chemokine (C-X-C motif) ligand 8 1.11898
SELL selectin L 1.09377
IL10 interleukin 10 1.07572
HMGB1 high mobility group box 1 1.07278
TLR4 toll-like receptor 4 1.06102
MYD88 myeloid differentiation primary response 88 1.05723
TLR2 toll-like receptor 2 1.04714
SELE selectin E 0.989379
CMKLR1 chemerin chemokine-like receptor 1 0.985585
LBP lipopolysaccharide binding protein 0.985164
CCL3 chemokine (C-C motif) ligand 3 0.978848
THYN1 thymocyte nuclear protein 1 0.977585
B2M beta-2-microglobulin 0.958287
ADA adenosine deaminase 0.917611
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.905675
NLRC4 NLR family, CARD domain containing 4 0.905265
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.905265
TRAM1 translocation associated membrane protein 1 0.899924
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 0.877376
FN1 fibronectin 1 0.864684
NOS2 nitric oxide synthase 2, inducible 0.864684
PCNP PEST proteolytic signal containing nuclear protein 0.858543
CD4 CD4 molecule 0.856087
TF transferrin 0.816334
CXCR2 chemokine (C-X-C motif) receptor 2 0.815514
ALOX5 arachidonate 5-lipoxygenase 0.815104
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.805667
CARD17 caspase recruitment domain family, member 17 0.798282
PLAT plasminogen activator, tissue 0.793771
ELANE elastase, neutrophil expressed 0.786803
PLG plasminogen 0.779841
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.772887
INS insulin 0.770435
RRBP1 ribosome binding protein 1 0.768801
AQP1 aquaporin 1 (Colton blood group) 0.762271
F3 coagulation factor III (thromboplastin, tissue factor) 0.762271
SELPLG selectin P ligand 0.758601
IL1A interleukin 1, alpha 0.755749
ABRA actin binding Rho activating protein 0.753306
ALPPL2 alkaline phosphatase, placental-like 2 0.75005
ALPP alkaline phosphatase, placental 0.749644
CCL13 chemokine (C-C motif) ligand 13 0.749237
ALPL alkaline phosphatase, liver/bone/kidney 0.74883
GPR32 G protein-coupled receptor 32 0.745985
HSF4 heat shock transcription factor 4 0.739894
TGFB1 transforming growth factor, beta 1 0.736243
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.732596
NLRP3 NLR family, pyrin domain containing 3 0.731381
TREM1 triggering receptor expressed on myeloid cells 1 0.730976
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.726929
CAT catalase 0.718039
MUCL1 mucin-like 1 0.716828
GPR18 G protein-coupled receptor 18 0.714005
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.706754
PLA2G1B phospholipase A2, group IB (pancreas) 0.694702
ANXA1 annexin A1 0.693499
CSN1S1 casein alpha s1 0.689893
CD79A CD79a molecule, immunoglobulin-associated alpha 0.67551
TBP TATA box binding protein 0.66596
MMP9 matrix metallopeptidase 9 0.650903
S100A9 S100 calcium binding protein A9 0.648138
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.647348
IPP intracisternal A particle-promoted polypeptide 0.642615
HTRA3 HtrA serine peptidase 3 0.639857
RRAGA Ras-related GTP binding A 0.622575
LYZ lysozyme 0.621792
RIPK2 receptor-interacting serine-threonine kinase 2 0.617486
TTR transthyretin 0.61162
PER1 period circadian clock 1 0.610057
PDZD11 PDZ domain containing 11 0.606933
COL3A1 collagen, type III, alpha 1 0.594454
VCAM1 vascular cell adhesion molecule 1 0.585887
CRCP CGRP receptor component 0.583552
LOX lysyl oxidase 0.57305
APOLD1 apolipoprotein L domain containing 1 0.561392
AZU1 azurocidin 1 0.548971
KAT8 K(lysine) acetyltransferase 8 0.548971
AVP arginine vasopressin 0.548583
NOD2 nucleotide-binding oligomerization domain containing 2 0.548195
CCL5 chemokine (C-C motif) ligand 5 0.541217
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.535409
POMC proopiomelanocortin 0.534248
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.533861
KNG1 kininogen 1 0.530381
CCR2 chemokine (C-C motif) receptor 2 0.528835
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.524202
CD93 CD93 molecule 0.522273
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2 0.517265
CTSG cathepsin G 0.516879
CATSPER1 cation channel, sperm associated 1 0.509959
CXCL10 chemokine (C-X-C motif) ligand 10 0.506507
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.505356
RAET1E retinoic acid early transcript 1E 0.503441
PTH parathyroid hormone 0.496557
HPR haptoglobin-related protein 0.495029
IL2 interleukin 2 0.491597
CD40 CD40 molecule, TNF receptor superfamily member 5 0.490454
SOD2 superoxide dismutase 2, mitochondrial 0.485885
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.485505
TREML1 triggering receptor expressed on myeloid cells-like 1 0.484364
PLAU plasminogen activator, urokinase 0.483985
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.482464
ADAM17 ADAM metallopeptidase domain 17 0.47753
PHF20 PHD finger protein 20 0.471089
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta 0.465416
PLXNB2 plexin B2 0.46466
QPCTL glutaminyl-peptide cyclotransferase-like 0.463527
CDSN corneodesmosin 0.462394
C1QTNF3 C1q and tumor necrosis factor related protein 3 0.462394
HP haptoglobin 0.459751
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.458996
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4 0.457864
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 0.455224
PIDD1 p53-induced death domain protein 1 0.448441
TLR9 toll-like receptor 9 0.440162
PNMA2 paraneoplastic Ma antigen 2 0.43941
PER2 period circadian clock 2 0.434524
REG1A regenerating islet-derived 1 alpha 0.429642
NLRP1 NLR family, pyrin domain containing 1 0.42664
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.425139
CD40LG CD40 ligand 0.425139
SEPT4 septin 4 0.424765
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 0.418768
DDN dendrin 0.418019
NCAPD2 non-SMC condensin I complex, subunit D2 0.417644
PLXNA4 plexin A4 0.413901
CCDC110 coiled-coil domain containing 110 0.413901
CD47 CD47 molecule 0.408666
FTH1 ferritin, heavy polypeptide 1 0.408292
FTL ferritin, light polypeptide 0.408292
ESAM endothelial cell adhesion molecule 0.408292
LRRC38 leucine rich repeat containing 38 0.407919
CYGB cytoglobin 0.406798
SST somatostatin 0.406425
VAMP8 vesicle-associated membrane protein 8 0.404931
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 0.402318
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.399334
ANPEP alanyl (membrane) aminopeptidase 0.397471
IL1R1 interleukin 1 receptor, type I 0.396725
HRH4 histamine receptor H4 0.393746
ASMT acetylserotonin O-methyltransferase 0.386679
CD69 CD69 molecule 0.386679
CNTFR ciliary neurotrophic factor receptor 0.386308
PLXNC1 plexin C1 0.385193
FPR2 formyl peptide receptor 2 0.382594
IL1RN interleukin 1 receptor antagonist 0.380368
CXCL2 chemokine (C-X-C motif) ligand 2 0.379626
REN renin 0.374438
ZNF10 zinc finger protein 10 0.374068
C3 complement component 3 0.373328
CALB2 calbindin 2 0.370368
LTF lactotransferrin 0.370368
EPO erythropoietin 0.366301
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.364085
PGP phosphoglycolate phosphatase 0.360764
TSPO translocator protein (18kDa) 0.358551
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) 0.353763
URI1 URI1, prefoldin-like chaperone 0.352659
PLAC8 placenta-specific 8 0.351923
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 0.351555
ALPI alkaline phosphatase, intestinal 0.351187
NOS3 nitric oxide synthase 3 (endothelial cell) 0.350084
SPHK1 sphingosine kinase 1 0.344941
C17ORF85 chromosome 17 open reading frame 85 0.343473
LTB4R leukotriene B4 receptor 0.343106
VEGFC vascular endothelial growth factor C 0.341272
OCLN occludin 0.339806
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.339073
IFNG interferon, gamma 0.331756
F11 coagulation factor XI 0.33066
CTSB cathepsin B 0.329565
SYK spleen tyrosine kinase 0.326646
HRH2 histamine receptor H2 0.325916
TXNL1 thioredoxin-like 1 0.325916
LEMD3 LEM domain containing 3 0.325187
TRIM37 tripartite motif containing 37 0.320817
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.32009
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.316092
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.314278
SUMF2 sulfatase modifying factor 2 0.31029
GABPA GA binding protein transcription factor, alpha subunit 60kDa 0.308842
LINS lines homolog (Drosophila) 0.306672
MC3R melanocortin 3 receptor 0.303059
PRTN3 proteinase 3 0.300894
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.298731
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.298011
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 0.298011
IL34 interleukin 34 0.298011
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.297651
CD300A CD300a molecule 0.297651
VIP vasoactive intestinal peptide 0.296931
AGER advanced glycosylation end product-specific receptor 0.293694
TLR6 toll-like receptor 6 0.292975
FRRS1L ferric-chelate reductase 1-like 0.292975
CTSC cathepsin C 0.292257
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.290821
CTGF connective tissue growth factor 0.289027
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.283655
INPP5J inositol polyphosphate-5-phosphatase J 0.281868
CD44 CD44 molecule (Indian blood group) 0.280439
NEO1 neogenin 1 0.280082
CREG1 cellular repressor of E1A-stimulated genes 1 0.277584
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.27687
LHFPL5 lipoma HMGIC fusion partner-like 5 0.274021
IL22RA2 interleukin 22 receptor, alpha 2 0.272953
CXCR1 chemokine (C-X-C motif) receptor 1 0.269043
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.268332
GLB1 galactosidase, beta 1 0.265494
NUBPL nucleotide binding protein-like 0.26514
DUSP1 dual specificity phosphatase 1 0.264431
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.264077
FRY furry homolog (Drosophila) 0.260184
SELK selenoprotein K 0.260184
LEP leptin 0.25983
LCN2 lipocalin 2 0.258064
CSF1 colony stimulating factor 1 (macrophage) 0.257005
CCL22 chemokine (C-C motif) ligand 22 0.256299
NRF1 nuclear respiratory factor 1 0.255241
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.253127
CNR2 cannabinoid receptor 2 (macrophage) 0.253127
IL15 interleukin 15 0.25207
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.251366
GAST gastrin 0.251015
ASIP agouti signaling protein 0.247501
DEPDC1 DEP domain containing 1 0.243645
FOXRED1 FAD-dependent oxidoreductase domain containing 1 0.243295
GGT1 gamma-glutamyltransferase 1 0.241546
IL2RA interleukin 2 receptor, alpha 0.235268
PDE1B phosphodiesterase 1B, calmodulin-dependent 0.233183
PPARG peroxisome proliferator-activated receptor gamma 0.231102
AFP alpha-fetoprotein 0.228679
CYTH1 cytohesin 1 0.227988
COL1A2 collagen, type I, alpha 2 0.225229
CPA3 carboxypeptidase A3 (mast cell) 0.223509
CLCF1 cardiotrophin-like cytokine factor 1 0.221793
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.220424
CSF1R colony stimulating factor 1 receptor 0.220081
CLIC2 chloride intracellular channel 2 0.217012
DAPK2 death-associated protein kinase 2 0.213621
PANX1 pannexin 1 0.213283
DAPK3 death-associated protein kinase 3 0.210589
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.209918
TYROBP TYRO protein tyrosine kinase binding protein 0.20658
RPS19 ribosomal protein S19 0.206248
MMP2 matrix metallopeptidase 2 0.204593
SAA2 serum amyloid A2 0.204263
TOB1 transducer of ERBB2, 1 0.201962
FAM120A family with sequence similarity 120A 0.200982
CCL4 chemokine (C-C motif) ligand 4 0.200656
OPRK1 opioid receptor, kappa 1 0.199356
GUSB glucuronidase, beta 0.198709
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.198064
VEGFA vascular endothelial growth factor A 0.197099
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.192344
PRKCQ protein kinase C, theta 0.192344
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.192031
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 0.191719
CD68 CD68 molecule 0.191408
BMP2K BMP2 inducible kinase 0.191097
IRAK2 interleukin-1 receptor-associated kinase 2 0.187415
GFER growth factor, augmenter of liver regeneration 0.18621
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.18591
PLXND1 plexin D1 0.185313
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.185313
CFL1 cofilin 1 (non-muscle) 0.182957
IL18 interleukin 18 0.182375
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.182375
CXCL5 chemokine (C-X-C motif) ligand 5 0.18151
ESRP1 epithelial splicing regulatory protein 1 0.181222
IL17A interleukin 17A 0.181222
CCL4L2 chemokine (C-C motif) ligand 4-like 2 0.180367
CPA4 carboxypeptidase A4 0.178403
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.176757
AOC3 amine oxidase, copper containing 3 0.175947
CMA1 chymase 1, mast cell 0.175947
CCL4L1 chemokine (C-C motif) ligand 4-like 1 0.175146
HHAT hedgehog acyltransferase 0.175146
SCIN scinderin 0.174354
TLR5 toll-like receptor 5 0.174093
CEMIP cell migration inducing protein, hyaluronan binding 0.171286
FASLG Fas ligand (TNF superfamily, member 6) 0.171286
CD209 CD209 molecule 0.171036
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.170789
HCK HCK proto-oncogene, Src family tyrosine kinase 0.16933
FGF2 fibroblast growth factor 2 (basic) 0.166319
TBK1 TANK-binding kinase 1 0.164571
IMMT inner membrane protein, mitochondrial 0.164571
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.164359
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.164149
AHSG alpha-2-HS-glycoprotein 0.163938
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.163523
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.162109
GGT2 gamma-glutamyltransferase 2 0.161716
RNF25 ring finger protein 25 0.161523
PRAMEF12 PRAME family member 12 0.160761
XPO4 exportin 4 0.159838
SLC7A4 solute carrier family 7, member 4 0.159124
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 0.158951
NSF N-ethylmaleimide-sensitive factor 0.158951
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.158778
ENGASE endo-beta-N-acetylglucosaminidase 0.158434
TLR7 toll-like receptor 7 0.158434