peritonitis Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A gastrointestinal system disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. Peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. The symptoms include abdominal pain and tenderness, fever, fluid in the abdomen, nausea, vomiting and low urine output. (Human Disease Ontology, DOID_8283)
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Genes

33 genes co-occuring with the biological term peritonitis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADA adenosine deaminase
CALCA calcitonin-related polypeptide alpha
CCL2 chemokine (C-C motif) ligand 2
CD40 CD40 molecule, TNF receptor superfamily member 5
CRP C-reactive protein, pentraxin-related
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
ELANE elastase, neutrophil expressed
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FOXL2 forkhead box L2
HMGB1 high mobility group box 1
IL17A interleukin 17A
IL1B interleukin 1, beta
IL6 interleukin 6
IL6R interleukin 6 receptor
LCN2 lipocalin 2
LDHA lactate dehydrogenase A
LEPQTL1 Leptin, serum levels of
LEPR leptin receptor
MUC16 mucin 16, cell surface associated
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NR5A1 nuclear receptor subfamily 5, group A, member 1
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
RIPK2 receptor-interacting serine-threonine kinase 2
S100A9 S100 calcium binding protein A9
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TREM1 triggering receptor expressed on myeloid cells 1