| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the perphenazine-1540 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGFG2 | ArfGAP with FG repeats 2 |
| AJAP1 | adherens junctions associated protein 1 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| APOC1 | apolipoprotein C-I |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ATF3 | activating transcription factor 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CD70 | CD70 molecule |
| CDK18 | cyclin-dependent kinase 18 |
| CDK6 | cyclin-dependent kinase 6 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CLDN17 | claudin 17 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| COL1A1 | collagen, type I, alpha 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DEAF1 | DEAF1 transcription factor |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EGR1 | early growth response 1 |
| FAM46C | family with sequence similarity 46, member C |
| FOXN2 | forkhead box N2 |
| FRK | fyn-related Src family tyrosine kinase |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GFER | growth factor, augmenter of liver regeneration |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSN | gelsolin |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A |
| HIST1H1D | histone cluster 1, H1d |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXA10 | homeobox A10 |
| HPX | hemopexin |
| ICAM1 | intercellular adhesion molecule 1 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL5RA | interleukin 5 receptor, alpha |
| INSIG1 | insulin induced gene 1 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| JUN | jun proto-oncogene |
| JUND | jun D proto-oncogene |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KDM6B | lysine (K)-specific demethylase 6B |
| KLHL24 | kelch-like family member 24 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LDLR | low density lipoprotein receptor |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| MMP10 | matrix metallopeptidase 10 |
| NOL10 | nucleolar protein 10 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PLAU | plasminogen activator, urokinase |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PQLC2 | PQ loop repeat containing 2 |
| PRPH | peripherin |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPL10L | ribosomal protein L10-like |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 |
| SH3BP2 | SH3-domain binding protein 2 |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC17A6 | solute carrier family 17 (vesicular glutamate transporter), member 6 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SSTR4 | somatostatin receptor 4 |
| SYBU | syntabulin (syntaxin-interacting) |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TCF4 | transcription factor 4 |
| TES | testin LIM domain protein |
| TEX15 | testis expressed 15 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIM2 | tripartite motif containing 2 |
| TRIM29 | tripartite motif containing 29 |
| TSC22D2 | TSC22 domain family, member 2 |
| TTC9 | tetratricopeptide repeat domain 9 |
| TUBA3C | tubulin, alpha 3c |
| USB1 | U6 snRNA biogenesis 1 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZNF500 | zinc finger protein 500 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| AXIN1 | axin 1 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CFD | complement factor D (adipsin) |
| CHMP6 | charged multivesicular body protein 6 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CPTP | ceramide-1-phosphate transfer protein |
| CTSF | cathepsin F |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DENND4A | DENN/MADD domain containing 4A |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
| DMTN | dematin actin binding protein |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DSCAM | Down syndrome cell adhesion molecule |
| EGFL7 | EGF-like-domain, multiple 7 |
| ENO3 | enolase 3 (beta, muscle) |
| ERF | Ets2 repressor factor |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM131A | family with sequence similarity 131, member A |
| FAM188A | family with sequence similarity 188, member A |
| FKBP5 | FK506 binding protein 5 |
| GRPR | gastrin-releasing peptide receptor |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H2AI | histone cluster 1, H2ai |
| HOXC10 | homeobox C10 |
| HPN | hepsin |
| HSPA1L | heat shock 70kDa protein 1-like |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL4R | interleukin 4 receptor |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| IPO8 | importin 8 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC730101 | uncharacterized LOC730101 |
| LRRC61 | leucine rich repeat containing 61 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MICALL2 | MICAL-like 2 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MSI1 | musashi RNA-binding protein 1 |
| NEUROD4 | neuronal differentiation 4 |
| NLRX1 | NLR family member X1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PER3 | period circadian clock 3 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLD2 | phospholipase D2 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| RAB30 | RAB30, member RAS oncogene family |
| RGL2 | ral guanine nucleotide dissociation stimulator-like 2 |
| RNF39 | ring finger protein 39 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SDC3 | syndecan 3 |
| SH2B3 | SH2B adaptor protein 3 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SPRYD7 | SPRY domain containing 7 |
| STRA6 | stimulated by retinoic acid 6 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TCTN2 | tectonic family member 2 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMC5 | transmembrane channel-like 5 |
| TMEM223 | transmembrane protein 223 |
| TRAIP | TRAF interacting protein |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| VEGFB | vascular endothelial growth factor B |
| VGF | VGF nerve growth factor inducible |
| WDR62 | WD repeat domain 62 |
| ZNF205 | zinc finger protein 205 |
| ZNF669 | zinc finger protein 669 |
| ZNF747 | zinc finger protein 747 |
| ZNF76 | zinc finger protein 76 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
