| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the perphenazine-1956 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM17 | ADAM metallopeptidase domain 17 |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| AVPR1B | arginine vasopressin receptor 1B |
| CBX6 | chromobox homolog 6 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDYL | chromodomain protein, Y-like |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CRELD2 | cysteine-rich with EGF-like domains 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYB561 | cytochrome b561 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DENND3 | DENN/MADD domain containing 3 |
| DHPS | deoxyhypusine synthase |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DNASE2 | deoxyribonuclease II, lysosomal |
| DUSP6 | dual specificity phosphatase 6 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFNA1 | ephrin-A1 |
| EIF1 | eukaryotic translation initiation factor 1 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FADS2 | fatty acid desaturase 2 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GPR161 | G protein-coupled receptor 161 |
| HBP1 | HMG-box transcription factor 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HMOX1 | heme oxygenase 1 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IL1RN | interleukin 1 receptor antagonist |
| IL24 | interleukin 24 |
| IL6 | interleukin 6 |
| INSIG1 | insulin induced gene 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JUND | jun D proto-oncogene |
| JUP | junction plakoglobin |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| KLHL3 | kelch-like family member 3 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LDLR | low density lipoprotein receptor |
| LDLRAP1 | low density lipoprotein receptor adaptor protein 1 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like |
| MICALL1 | MICAL-like 1 |
| MMP1 | matrix metallopeptidase 1 |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MYL9 | myosin, light chain 9, regulatory |
| NDRG1 | N-myc downstream regulated 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| NRBP1 | nuclear receptor binding protein 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PLAUR | plasminogen activator, urokinase receptor |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTAFR | platelet-activating factor receptor |
| PYGB | phosphorylase, glycogen; brain |
| RGS4 | regulator of G-protein signaling 4 |
| RHOC | ras homolog family member C |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SQLE | squalene epoxidase |
| SQSTM1 | sequestosome 1 |
| STC1 | stanniocalcin 1 |
| STK19 | serine/threonine kinase 19 |
| STX3 | syntaxin 3 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM161A | transmembrane protein 161A |
| TMEM50B | transmembrane protein 50B |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRIB3 | tribbles pseudokinase 3 |
| WASL | Wiskott-Aldrich syndrome-like |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZNF165 | zinc finger protein 165 |
| ZNF408 | zinc finger protein 408 |
| Symbol | Name |
|---|---|
| ACTR1B | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BLM | Bloom syndrome, RecQ helicase-like |
| BTNL3 | butyrophilin-like 3 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| CBR4 | carbonyl reductase 4 |
| CCBL2 | cysteine conjugate-beta lyase 2 |
| CCDC109B | coiled-coil domain containing 109B |
| CCDC176 | coiled-coil domain containing 176 |
| CCDC25 | coiled-coil domain containing 25 |
| CCNA2 | cyclin A2 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDC7 | cell division cycle 7 |
| CDCA4 | cell division cycle associated 4 |
| CENPM | centromere protein M |
| CLUH | clustered mitochondria (cluA/CLU1) homolog |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CROT | carnitine O-octanoyltransferase |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| DHRS1 | dehydrogenase/reductase (SDR family) member 1 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| E2F8 | E2F transcription factor 8 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 |
| ERBB2IP | erbb2 interacting protein |
| ERI2 | ERI1 exoribonuclease family member 2 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FAF1 | Fas (TNFRSF6) associated factor 1 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAM188A | family with sequence similarity 188, member A |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FANCC | Fanconi anemia, complementation group C |
| FASTKD1 | FAST kinase domains 1 |
| FBXL14 | F-box and leucine-rich repeat protein 14 |
| FBXO5 | F-box protein 5 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FTO | fat mass and obesity associated |
| GALNS | galactosamine (N-acetyl)-6-sulfatase |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
| GRHL2 | grainyhead-like 2 (Drosophila) |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFNA17 | interferon, alpha 17 |
| IFT57 | intraflagellar transport 57 |
| IRS1 | insulin receptor substrate 1 |
| KIF20B | kinesin family member 20B |
| KIFC1 | kinesin family member C1 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LMBR1L | limb development membrane protein 1-like |
| MB | myoglobin |
| METTL8 | methyltransferase like 8 |
| MFF | mitochondrial fission factor |
| MNX1 | motor neuron and pancreas homeobox 1 |
| NEMF | nuclear export mediator factor |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NOL11 | nucleolar protein 11 |
| NOP2 | NOP2 nucleolar protein |
| NUP43 | nucleoporin 43kDa |
| OGFRL1 | opioid growth factor receptor-like 1 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PCYOX1L | prenylcysteine oxidase 1 like |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLK2 | polo-like kinase 2 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRMT3 | protein arginine methyltransferase 3 |
| PRPF38B | pre-mRNA processing factor 38B |
| PTCD1 | pentatricopeptide repeat domain 1 |
| QTRTD1 | queuine tRNA-ribosyltransferase domain containing 1 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RBM41 | RNA binding motif protein 41 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| SDAD1 | SDA1 domain containing 1 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SOD3 | superoxide dismutase 3, extracellular |
| STIL | SCL/TAL1 interrupting locus |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TASP1 | taspase, threonine aspartase, 1 |
| THAP7 | THAP domain containing 7 |
| TMEM177 | transmembrane protein 177 |
| TMEM260 | transmembrane protein 260 |
| TRHDE | thyrotropin-releasing hormone degrading enzyme |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| VASP | vasodilator-stimulated phosphoprotein |
| WDR3 | WD repeat domain 3 |
| WDR5B | WD repeat domain 5B |
| ZBTB11 | zinc finger and BTB domain containing 11 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 |
| ZNF239 | zinc finger protein 239 |
| ZNF35 | zinc finger protein 35 |
| ZNHIT6 | zinc finger, HIT-type containing 6 |
