perphenazine-4637 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the perphenazine-4637 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGRF5 adhesion G protein-coupled receptor F5
ADRBK1 adrenergic, beta, receptor kinase 1
AHNAK AHNAK nucleoprotein
ALDOB aldolase B, fructose-bisphosphate
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATF3 activating transcription factor 3
BCL2 B-cell CLL/lymphoma 2
C1ORF116 chromosome 1 open reading frame 116
C20ORF195 chromosome 20 open reading frame 195
C8ORF4 chromosome 8 open reading frame 4
CA5B carbonic anhydrase VB, mitochondrial
CCDC7 coiled-coil domain containing 7
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN6 chloride channel, voltage-sensitive 6
COBL cordon-bleu WH2 repeat protein
COL5A1 collagen, type V, alpha 1
CRELD1 cysteine-rich with EGF-like domains 1
CTH cystathionine gamma-lyase
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DOK4 docking protein 4
DPY19L1P1 DPY19L1 pseudogene 1
EGR1 early growth response 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
FCGBP Fc fragment of IgG binding protein
FDPS farnesyl diphosphate synthase
FLJ11292
FUBP1 far upstream element (FUSE) binding protein 1
FYB FYN binding protein
GABARAPL1 GABA(A) receptor-associated protein like 1
GFI1 growth factor independent 1 transcription repressor
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRM8 glutamate receptor, metabotropic 8
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DOA major histocompatibility complex, class II, DO alpha
HMOX1 heme oxygenase 1
HR hair growth associated
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ICA1 islet cell autoantigen 1, 69kDa
ICOSLG inducible T-cell co-stimulator ligand
IFIH1 interferon induced with helicase C domain 1
IL6 interleukin 6
INSIG1 insulin induced gene 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JUND jun D proto-oncogene
KAT5 K(lysine) acetyltransferase 5
KDM6B lysine (K)-specific demethylase 6B
KLHL22 kelch-like family member 22
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LDLR low density lipoprotein receptor
LEF1 lymphoid enhancer-binding factor 1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LOC390998 ribosomal protein L10 pseudogene
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MMP10 matrix metallopeptidase 10
NIPAL3 NIPA-like domain containing 3
NUPR1 nuclear protein, transcriptional regulator, 1
PADI4 peptidyl arginine deiminase, type IV
PAOX polyamine oxidase (exo-N4-amino)
PCDH1 protocadherin 1
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDGFA platelet-derived growth factor alpha polypeptide
PDPN podoplanin
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRKG2 protein kinase, cGMP-dependent, type II
PRMT2IP PRMT2 interacting protein
RARG retinoic acid receptor, gamma
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RFXAP regulatory factor X-associated protein
RGS4 regulator of G-protein signaling 4
SAMD4A sterile alpha motif domain containing 4A
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SLA Src-like-adaptor
SND1-IT1 SND1 intronic transcript 1
SNRPN small nuclear ribonucleoprotein polypeptide N
SQSTM1 sequestosome 1
STOML1 stomatin (EPB72)-like 1
SYT1 synaptotagmin I
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TDRD1 tudor domain containing 1
TET3 tet methylcytosine dioxygenase 3
TFR2 transferrin receptor 2
TRIB3 tribbles pseudokinase 3
TSSK2 testis-specific serine kinase 2
ZBTB39 zinc finger and BTB domain containing 39
ZNF219 zinc finger protein 219
ZNF589 zinc finger protein 589
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADGRB2 adhesion G protein-coupled receptor B2
ADGRE2 adhesion G protein-coupled receptor E2
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMH anti-Mullerian hormone
ASTN1 astrotactin 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
C1ORF159 chromosome 1 open reading frame 159
C1QTNF1 C1q and tumor necrosis factor related protein 1
C9ORF40 chromosome 9 open reading frame 40
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNR2 cannabinoid receptor 2 (macrophage)
CNTLN centlein, centrosomal protein
CRISP2 cysteine-rich secretory protein 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND2D DENN/MADD domain containing 2D
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DLK2 delta-like 2 homolog (Drosophila)
ERCC4 excision repair cross-complementation group 4
FAM13C family with sequence similarity 13, member C
FILIP1L filamin A interacting protein 1-like
FRMPD1 FERM and PDZ domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
GLS2 glutaminase 2 (liver, mitochondrial)
GMPR guanosine monophosphate reductase
GRAMD1C GRAM domain containing 1C
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST1H4E histone cluster 1, H4e
HOXA1 homeobox A1
HRH2 histamine receptor H2
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
ICOS inducible T-cell co-stimulator
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KIAA0319L KIAA0319-like
KIAA1456 KIAA1456
KRT31 keratin 31, type I
KRTAP1-3 keratin associated protein 1-3
LAMC3 laminin, gamma 3
LIG4 ligase IV, DNA, ATP-dependent
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPAR4 lysophosphatidic acid receptor 4
LRP5L low density lipoprotein receptor-related protein 5-like
MAP3K7CL MAP3K7 C-terminal like
MOB3B MOB kinase activator 3B
MX1 MX dynamin-like GTPase 1
MYLIP myosin regulatory light chain interacting protein
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NPM3 nucleophosmin/nucleoplasmin 3
NTF3 neurotrophin 3
NTSR1 neurotensin receptor 1 (high affinity)
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDE12 phosphodiesterase 12
PDE8B phosphodiesterase 8B
PLAC8 placenta-specific 8
PLVAP plasmalemma vesicle associated protein
POLH polymerase (DNA directed), eta
PRM2 protamine 2
PROX1 prospero homeobox 1
PTCD2 pentatricopeptide repeat domain 2
PTTG2 pituitary tumor-transforming 2
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD51B RAD51 paralog B
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RFX7 regulatory factor X, 7
RHOBTB2 Rho-related BTB domain containing 2
RIMBP2 RIMS binding protein 2
RNF126P1 ring finger protein 126 pseudogene 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SLC12A9 solute carrier family 12, member 9
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SOX30 SRY (sex determining region Y)-box 30
SPEG SPEG complex locus
STARD5 StAR-related lipid transfer (START) domain containing 5
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMC5 transmembrane channel-like 5
TMPRSS4 transmembrane protease, serine 4
TRIM45 tripartite motif containing 45
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZNF124 zinc finger protein 124
ZNF197 zinc finger protein 197
ZNF239 zinc finger protein 239
ZNF702P zinc finger protein 702, pseudogene
ZNF747 zinc finger protein 747
ZNF816 zinc finger protein 816
ZSCAN2 zinc finger and SCAN domain containing 2