perphenazine-5698 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the perphenazine-5698 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AJAP1 adherens junctions associated protein 1
ANG angiogenin, ribonuclease, RNase A family, 5
ATF3 activating transcription factor 3
ATXN2L ataxin 2-like
ATXN7L1 ataxin 7-like 1
CCDC71 coiled-coil domain containing 71
CEMIP cell migration inducing protein, hyaluronan binding
CFAP69 cilia and flagella associated protein 69
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
COL3A1 collagen, type III, alpha 1
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CRHR1 corticotropin releasing hormone receptor 1
CXCR4 chemokine (C-X-C motif) receptor 4
DDIT3 DNA-damage-inducible transcript 3
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP6 dual specificity phosphatase 6
E2F5 E2F transcription factor 5, p130-binding
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM129A family with sequence similarity 129, member A
FAM46C family with sequence similarity 46, member C
FDPS farnesyl diphosphate synthase
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAST gastrin
GEM GTP binding protein overexpressed in skeletal muscle
GP2 glycoprotein 2 (zymogen granule membrane)
GPATCH3 G patch domain containing 3
HBB hemoglobin, beta
HIPK2 homeodomain interacting protein kinase 2
HMOX1 heme oxygenase 1
HPCAL4 hippocalcin like 4
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
KLHL24 kelch-like family member 24
KRT6B keratin 6B, type II
LEF1 lymphoid enhancer-binding factor 1
LIF leukemia inhibitory factor
LPIN1 lipin 1
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRP12 low density lipoprotein receptor-related protein 12
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEB2 melanoma antigen family B2
MALL mal, T-cell differentiation protein-like
MAP1B microtubule-associated protein 1B
MIER2 mesoderm induction early response 1, family member 2
MMP25 matrix metallopeptidase 25
NDRG2 NDRG family member 2
NRG1 neuregulin 1
NT5E 5'-nucleotidase, ecto (CD73)
OLFM4 olfactomedin 4
OR7A10 olfactory receptor, family 7, subfamily A, member 10
OSGIN1 oxidative stress induced growth inhibitor 1
PARP11 poly (ADP-ribose) polymerase family, member 11
PAX2 paired box 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKP1 plakophilin 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
RAI2 retinoic acid induced 2
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RRBP1 ribosome binding protein 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC39A9 solute carrier family 39, member 9
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
SPTBN1 spectrin, beta, non-erythrocytic 1
SPTBN2 spectrin, beta, non-erythrocytic 2
STRA6 stimulated by retinoic acid 6
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TCP11L1 t-complex 11, testis-specific-like 1
TDRKH tudor and KH domain containing
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMPRSS15 transmembrane protease, serine 15
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TPSG1 tryptase gamma 1
TRIB2 tribbles pseudokinase 2
TRIM2 tripartite motif containing 2
UBXN1 UBX domain protein 1
UPK3B uroplakin 3B
UPP1 uridine phosphorylase 1
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VLDLR very low density lipoprotein receptor
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
XYLB xylulokinase homolog (H. influenzae)
YIPF4 Yip1 domain family, member 4
YY2 YY2 transcription factor
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF165 zinc finger protein 165
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ACTL8 actin-like 8
ADAP2 ArfGAP with dual PH domains 2
AGMAT agmatine ureohydrolase (agmatinase)
AKAP12 A kinase (PRKA) anchor protein 12
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ATP10D ATPase, class V, type 10D
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL9 B-cell CLL/lymphoma 9
BMP4 bone morphogenetic protein 4
BST2 bone marrow stromal cell antigen 2
C1ORF105 chromosome 1 open reading frame 105
CAPG capping protein (actin filament), gelsolin-like
CAPN5 calpain 5
CASS4 Cas scaffolding protein family member 4
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC121 coiled-coil domain containing 121
CCDC85C coiled-coil domain containing 85C
CDHR2 cadherin-related family member 2
CEP131 centrosomal protein 131kDa
CIC capicua transcriptional repressor
CIDEB cell death-inducing DFFA-like effector b
CXORF21 chromosome X open reading frame 21
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DGKE diacylglycerol kinase, epsilon 64kDa
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNM1 dynamin 1
DRD1 dopamine receptor D1
EFNA3 ephrin-A3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM131A family with sequence similarity 131, member A
FAM198B family with sequence similarity 198, member B
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
FURIN furin (paired basic amino acid cleaving enzyme)
GLS2 glutaminase 2 (liver, mitochondrial)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR3 G protein-coupled receptor 3
GSTA4 glutathione S-transferase alpha 4
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HOXD11 homeobox D11
HPN hepsin
HPS6 Hermansky-Pudlak syndrome 6
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
KIAA0319L KIAA0319-like
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAX1 lymphocyte transmembrane adaptor 1
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRRC37A3 leucine rich repeat containing 37, member A3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MYL5 myosin, light chain 5, regulatory
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OCA2 oculocutaneous albinism II
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PGBD5 piggyBac transposable element derived 5
PGR progesterone receptor
PHEX phosphate regulating endopeptidase homolog, X-linked
PITX2 paired-like homeodomain 2
PODNL1 podocan-like 1
PRMT7 protein arginine methyltransferase 7
PRR4 proline rich 4 (lacrimal)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RGS19 regulator of G-protein signaling 19
RIN2 Ras and Rab interactor 2
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPGRIP1L RPGRIP1-like
S100A2 S100 calcium binding protein A2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC35F5 solute carrier family 35, member F5
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLMO1 slowmo homolog 1 (Drosophila)
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STARD3 StAR-related lipid transfer (START) domain containing 3
SYNC syncoilin, intermediate filament protein
TBR1 T-box, brain, 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TMPRSS3 transmembrane protease, serine 3
TRABD TraB domain containing
TREM1 triggering receptor expressed on myeloid cells 1
TTC30A tetratricopeptide repeat domain 30A
UNC93B1 unc-93 homolog B1 (C. elegans)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZBTB22 zinc finger and BTB domain containing 22
ZNF408 zinc finger protein 408
ZNF428 zinc finger protein 428
ZNF675 zinc finger protein 675
ZNF862 zinc finger protein 862