| Dataset | HPO Gene-Disease Associations |
| Category | disease or phenotype associations |
| Type | phenotype |
| Description | Hemoglobin F (HbF) contains two globin alpha chains and two globin gamma chains. It is the main form of hemoglobin in the fetus during the last seven months of intrauterine development and in the half year of postnatal life. In adults it normally makes up less than one percent of all hemoglobiin. This term refers to an increase in HbF above this limit. In beta thalassemia major, it may represent over 90 percent of all hemoglobin, and in beta thalassemia minor it may make up between 0.5 to 4 percent. (Human Phenotype Ontology, HP_0011904) |
| External Link | http://compbio.charite.de/hpoweb/showterm?id=HP:0011904 |
| Similar Terms | |
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6 genes associated with the persistence of hemoglobin f phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.
