| Dataset | MPO Gene-Phenotype Associations |
| Category | disease or phenotype associations |
| Type | phenotype |
| Description | persistence of the right dorsal aorta after development; the right dorsal aorta normally regresses but when it persists, a double aortic arch develops; if the left dorsal aorta also regresses, a right aortic arch forms (Mammalian Phenotype Ontology, MP_0010572) |
| External Link | http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010572 |
| Similar Terms | |
| Downloads & Tools |
7 gene mutations causing the persistent right dorsal aorta phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
| Symbol | Name |
|---|---|
| ECE1 | endothelin converting enzyme 1 |
| EDNRA | endothelin receptor type A |
| PAX3 | paired box 3 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TGFB2 | transforming growth factor, beta 2 |
| VEGFA | vascular endothelial growth factor A |
