persistent Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

364 genes co-occuring with the biological term persistent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACE angiotensin I converting enzyme
ADAM33 ADAM metallopeptidase domain 33
ADCY1 adenylate cyclase 1 (brain)
ADGRL3 adhesion G protein-coupled receptor L3
ADIPOR1 adiponectin receptor 1
ADPGK ADP-dependent glucokinase
ADRB2 adrenoceptor beta 2, surface
ADRBK1 adrenergic, beta, receptor kinase 1
AFP alpha-fetoprotein
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHR aryl hydrocarbon receptor
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX12 arachidonate 12-lipoxygenase
ALX4 ALX homeobox 4
AMH anti-Mullerian hormone
AMHR2 anti-Mullerian hormone receptor, type II
ANGPT1 angiopoietin 1
ANXA5 annexin A5
APCS amyloid P component, serum
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARF6 ADP-ribosylation factor 6
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ATOH7 atonal homolog 7 (Drosophila)
ATR ATR serine/threonine kinase
BCL2L1 BCL2-like 1
BDNF brain-derived neurotrophic factor
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BOD1 biorientation of chromosomes in cell division 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTNL2 butyrophilin-like 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C3AR1 complement component 3a receptor 1
C5AR1 complement component 5a receptor 1
C9ORF72 chromosome 9 open reading frame 72
CALCA calcitonin-related polypeptide alpha
CAV1 caveolin 1, caveolae protein, 22kDa
CAV3 caveolin 3
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCND1 cyclin D1
CCNE1 cyclin E1
CCR2 chemokine (C-C motif) receptor 2
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD1A CD1a molecule
CD27 CD27 molecule
CD274 CD274 molecule
CD4 CD4 molecule
CD40LG CD40 ligand
CD46 CD46 molecule, complement regulatory protein
CD70 CD70 molecule
CDA cytidine deaminase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CFLAR CASP8 and FADD-like apoptosis regulator
CHEK1 checkpoint kinase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHKA choline kinase alpha
CHUK conserved helix-loop-helix ubiquitous kinase
CIITA class II, major histocompatibility complex, transactivator
CISH cytokine inducible SH2-containing protein
CNTNAP2 contactin associated protein-like 2
COL2A1 collagen, type II, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A4 collagen, type IV, alpha 4
COMT catechol-O-methyltransferase
CREB1 cAMP responsive element binding protein 1
CRH corticotropin releasing hormone
CRHR1 corticotropin releasing hormone receptor 1
CRP C-reactive protein, pentraxin-related
CST3 cystatin C
CTGF connective tissue growth factor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CUX1 cut-like homeobox 1
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CYBB cytochrome b-245, beta polypeptide
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DCC DCC netrin 1 receptor
DDIT3 DNA-damage-inducible transcript 3
DEFB1 defensin, beta 1
DEFB103B defensin, beta 103B
DPP4 dipeptidyl-peptidase 4
DRD4 dopamine receptor D4
DUSP1 dual specificity phosphatase 1
E2F1 E2F transcription factor 1
EDN1 endothelin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EPAS1 endothelial PAS domain protein 1
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC3 excision repair cross-complementation group 3
ERCC4 excision repair cross-complementation group 4
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EXOG endo/exonuclease (5'-3'), endonuclease G-like
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F10 coagulation factor X
F11 coagulation factor XI
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F5 coagulation factor V (proaccelerin, labile factor)
F8 coagulation factor VIII, procoagulant component
FANCD2 Fanconi anemia, complementation group D2
FAS Fas cell surface death receptor
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF1 fibroblast growth factor 1 (acidic)
FGFR2 fibroblast growth factor receptor 2
FLG filaggrin
FLG2 filaggrin family member 2
FLNA filamin A, alpha
FLT3 fms-related tyrosine kinase 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
FOXF1 forkhead box F1
FOXO1 forkhead box O1
FOXP2 forkhead box P2
FOXP3 forkhead box P3
FRS2 fibroblast growth factor receptor substrate 2
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB2 GRB2-associated binding protein 2
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA6 GATA binding protein 6
GCK glucokinase (hexokinase 4)
GDF5 growth differentiation factor 5
GHRL ghrelin/obestatin prepropeptide
GJB2 gap junction protein, beta 2, 26kDa
GK glycerol kinase
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRK5 G protein-coupled receptor kinase 5
GSTP1 glutathione S-transferase pi 1
GUCA1A guanylate cyclase activator 1A (retina)
H2AFX H2A histone family, member X
HADH hydroxyacyl-CoA dehydrogenase
HAS2 hyaluronan synthase 2
HAVCR2 hepatitis A virus cellular receptor 2
HBB hemoglobin, beta
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HNF4A hepatocyte nuclear factor 4, alpha
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ICAM1 intercellular adhesion molecule 1
IFN1@ interferon, type 1, cluster
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IL10 interleukin 10
IL10RB interleukin 10 receptor, beta
IL12B interleukin 12B
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL18 interleukin 18
IL1B interleukin 1, beta
IL1R2 interleukin 1 receptor, type II
IL1RAP interleukin 1 receptor accessory protein
IL2 interleukin 2
IL21 interleukin 21
IL27 interleukin 27
IL33 interleukin 33
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IL6R interleukin 6 receptor
INSL3 insulin-like 3 (Leydig cell)
IRAK3 interleukin-1 receptor-associated kinase 3
IRF1 interferon regulatory factor 1
IRF7 interferon regulatory factor 7
IRS1 insulin receptor substrate 1
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIF1C kinesin family member 1C
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KLK3 kallikrein-related peptidase 3
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT5 keratin 5, type II
LCN2 lipocalin 2
LCT lactase
LEP leptin
LGALS9 lectin, galactoside-binding, soluble, 9
LYN LYN proto-oncogene, Src family tyrosine kinase
MAOA monoamine oxidase A
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MBL2 mannose-binding lectin (protein C) 2, soluble
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEIS1 Meis homeobox 1
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MICA MHC class I polypeptide-related sequence A
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR106B microRNA 106b
MIR122 microRNA 122
MIR146A microRNA 146a
MIR192 microRNA 192
MKI67 marker of proliferation Ki-67
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MST1R macrophage stimulating 1 receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MX1 MX dynamin-like GTPase 1
MXD3 MAX dimerization protein 3
MYH11 myosin, heavy chain 11, smooth muscle
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NF1 neurofibromin 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NPPC natriuretic peptide C
NPY neuropeptide Y
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
ODC1 ornithine decarboxylase 1
OXTR oxytocin receptor
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAX8 paired box 8
PCA3 prostate cancer associated 3 (non-protein coding)
PDCD1 programmed cell death 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PECAM1 platelet/endothelial cell adhesion molecule 1
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PGF placental growth factor
PGR progesterone receptor
PHB prohibitin
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLK4 polo-like kinase 4
PML promyelocytic leukemia
PPARA peroxisome proliferator-activated receptor alpha
PRKCD protein kinase C, delta
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTPRC protein tyrosine phosphatase, receptor type, C
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RB1 retinoblastoma 1
RCC2 regulator of chromosome condensation 2
RETN resistin
RHOH ras homolog family member H
RNF11 ring finger protein 11
RPE65 retinal pigment epithelium-specific protein 65kDa
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX1 runt-related transcription factor 1
S100B S100 calcium binding protein B
S1PR1 sphingosine-1-phosphate receptor 1
SAA1 serum amyloid A1
SALL4 spalt-like transcription factor 4
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN1B sodium channel, voltage gated, type I beta subunit
SCN4A sodium channel, voltage gated, type IV alpha subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SELE selectin E
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SFTPA1 surfactant protein A1
SHH sonic hedgehog
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLC45A2 solute carrier family 45, member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMAD1 SMAD family member 1
SMYD3 SET and MYND domain containing 3
SNAI1 snail family zinc finger 1
SNAPIN SNAP-associated protein
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SPI1 Spi-1 proto-oncogene
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
T T, brachyury homolog (mouse)
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TDG thymine-DNA glycosylase
TF transferrin
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNC tenascin C
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNNI3 troponin I type 3 (cardiac)
TP53 tumor protein p53
TPH1 tryptophan hydroxylase 1
TPH2 tryptophan hydroxylase 2
TPP1 tripeptidyl peptidase I
TREX1 three prime repair exonuclease 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TSG101 tumor susceptibility 101
TSHR thyroid stimulating hormone receptor
TTK TTK protein kinase
UBC ubiquitin C
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VWF von Willebrand factor
WNT2 wingless-type MMTV integration site family member 2
WT1 Wilms tumor 1