perturbation Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

128 genes co-occuring with the biological term perturbation in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
APLNR apelin receptor
APOA1 apolipoprotein A-I
ARF1 ADP-ribosylation factor 1
ATF2 activating transcription factor 2
ATF6 activating transcription factor 6
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
BCL2 B-cell CLL/lymphoma 2
BDKRB2 bradykinin receptor B2
BEST1 bestrophin 1
BEST2 bestrophin 2
BID BH3 interacting domain death agonist
BRCA1 breast cancer 1, early onset
BTK Bruton agammaglobulinemia tyrosine kinase
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCNB1 cyclin B1
CD28 CD28 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CERS6 ceramide synthase 6
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CRYAA crystallin, alpha A
CXCL12 chemokine (C-X-C motif) ligand 12
CYSLTR2 cysteinyl leukotriene receptor 2
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DEFB103B defensin, beta 103B
DSG1 desmoglein 1
EGFR epidermal growth factor receptor
ELAC2 elaC ribonuclease Z 2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FASN fatty acid synthase
FLNC filamin C, gamma
FOXO3 forkhead box O3
FXYD3 FXYD domain containing ion transport regulator 3
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GJB2 gap junction protein, beta 2, 26kDa
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HBB hemoglobin, beta
HNF1A HNF1 homeobox A
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA4 heat shock 70kDa protein 4
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IAPP islet amyloid polypeptide
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFI27 interferon, alpha-inducible protein 27
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1B interleukin 1, beta
IL7R interleukin 7 receptor
ILF3 interleukin enhancer binding factor 3, 90kDa
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDR kinase insert domain receptor
MAPK1 mitogen-activated protein kinase 1
MAPT microtubule-associated protein tau
MARK2 MAP/microtubule affinity-regulating kinase 2
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEGF8 multiple EGF-like-domains 8
MGMT O-6-methylguanine-DNA methyltransferase
MIR21 microRNA 21
MIR32 microRNA 32
MMP10 matrix metallopeptidase 10
MMP2 matrix metallopeptidase 2
MOGS mannosyl-oligosaccharide glucosidase
MOV10 Mov10 RISC complex RNA helicase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUS81 MUS81 structure-specific endonuclease subunit
MYBPC3 myosin binding protein C, cardiac
PACS1 phosphofurin acidic cluster sorting protein 1
PDYN prodynorphin
PEA15 phosphoprotein enriched in astrocytes 15
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G2F phospholipase A2, group IIF
PNCK pregnancy up-regulated nonubiquitous CaM kinase
PTEN phosphatase and tensin homolog
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTK2 protein tyrosine kinase 2
RAP1A RAP1A, member of RAS oncogene family
RHO rhodopsin
RNF11 ring finger protein 11
RPL11 ribosomal protein L11
RPL29 ribosomal protein L29
RPL30 ribosomal protein L30
RPL5 ribosomal protein L5
RXRA retinoid X receptor, alpha
S100A11 S100 calcium binding protein A11
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SP1 Sp1 transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
SULF2 sulfatase 2
TADA3 transcriptional adaptor 3
TARDBP TAR DNA binding protein
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TRIB1 tribbles pseudokinase 1
UGDH UDP-glucose 6-dehydrogenase
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VEGFA vascular endothelial growth factor A
VIM vimentin
WASL Wiskott-Aldrich syndrome-like
WRN Werner syndrome, RecQ helicase-like
ZFYVE9 zinc finger, FYVE domain containing 9