pertussis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A commensal bacterial infectious disease that results_in inflammation located_in respiratory tract, has_material_basis_in Bordetella pertussis, or has_material_basis_in Bordetella parapertussis, which produce toxins that paralyze the cilia of the respiratory epithelial cells. The infection is characterized by a prolonged, high-pitched, deeply indrawn breath (whoop). (Human Disease Ontology, DOID_1116)
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Genes

178 genes co-occuring with the disease pertussis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
DPT dermatopontin 2.97729
CD79A CD79a molecule, immunoglobulin-associated alpha 1.79525
ADCY2 adenylate cyclase 2 (brain) 1.54849
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.40789
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.40701
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.40045
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 1.3821
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 1.34853
RLIM ring finger protein, LIM domain interacting 1.30663
PARP1 poly (ADP-ribose) polymerase 1 1.20959
NPW neuropeptide W 1.08202
SAC3D1 SAC3 domain containing 1 0.968761
ART3 ADP-ribosyltransferase 3 0.949102
GPR101 G protein-coupled receptor 101 0.941196
ADPRHL2 ADP-ribosylhydrolase like 2 0.930828
CSN1S1 casein alpha s1 0.883521
TLR4 toll-like receptor 4 0.870006
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 0.831099
CD4 CD4 molecule 0.823308
NELFCD negative elongation factor complex member C/D 0.820847
MCHR2 melanin-concentrating hormone receptor 2 0.811411
MBP myelin basic protein 0.807308
SLC38A4 solute carrier family 38, member 4 0.801154
HES5 hes family bHLH transcription factor 5 0.767167
IL1B interleukin 1, beta 0.755342
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.755342
PHF5A PHD finger protein 5A 0.742329
INS insulin 0.737865
ALB albumin 0.73746
EEF2 eukaryotic translation elongation factor 2 0.706754
RHO rhodopsin 0.703938
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.694702
PRRC2A proline-rich coiled-coil 2A 0.682693
SRPX2 sushi-repeat containing protein, X-linked 2 0.669538
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 0.647743
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.64577
MCHR1 melanin-concentrating hormone receptor 1 0.645375
ZNF185 zinc finger protein 185 (LIM domain) 0.640251
IL5 interleukin 5 0.639463
SCN1A sodium channel, voltage gated, type I alpha subunit 0.626495
PLA2G1B phospholipase A2, group IB (pancreas) 0.622183
DOLK dolichol kinase 0.617877
CNTN5 contactin 5 0.612792
IL4 interleukin 4 0.595233
BARX1 BARX homeobox 1 0.590169
SUMF2 sulfatase modifying factor 2 0.587444
RBP3 retinol binding protein 3, interstitial 0.582773
SRGN serglycin 0.579272
ERAS ES cell expressed Ras 0.577327
UBASH3B ubiquitin associated and SH3 domain containing B 0.574605
KNG1 kininogen 1 0.566054
TNF tumor necrosis factor 0.564112
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.561004
TOX thymocyte selection-associated high mobility group box 0.549747
POMC proopiomelanocortin 0.539667
RGS11 regulator of G-protein signaling 11 0.524588
SAG S-antigen; retina and pineal gland (arrestin) 0.523816
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.509576
TSPO translocator protein (18kDa) 0.490454
CSF1R colony stimulating factor 1 receptor 0.488549
VIP vasoactive intestinal peptide 0.469197
TICAM1 toll-like receptor adaptor molecule 1 0.455224
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.442418
WAC WW domain containing adaptor with coiled-coil 0.440538
IARS isoleucyl-tRNA synthetase 0.434899
CCDC130 coiled-coil domain containing 130 0.430768
C5AR1 complement component 5a receptor 1 0.430017
DEGS1 delta(4)-desaturase, sphingolipid 1 0.429642
ACSL1 acyl-CoA synthetase long-chain family member 1 0.426265
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 0.425514
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 0.416521
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.411283
IL2 interleukin 2 0.40904
EMILIN1 elastin microfibril interfacer 1 0.404931
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.392629
IL10 interleukin 10 0.391885
DEFB1 defensin, beta 1 0.385193
SSTR1 somatostatin receptor 1 0.383337
CCR7 chemokine (C-C motif) receptor 7 0.38111
ARSI arylsulfatase family, member I 0.379997
OPRM1 opioid receptor, mu 1 0.374068
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.362609
PER1 period circadian clock 1 0.362239
VIPR2 vasoactive intestinal peptide receptor 2 0.361133
ENSA endosulfine alpha 0.360764
ADCY4 adenylate cyclase 4 0.359289
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 0.358183
LYZ lysozyme 0.357446
ADCY7 adenylate cyclase 7 0.339073
ITCH itchy E3 ubiquitin protein ligase 0.338341
CD53 CD53 molecule 0.331025
NOTO notochord homeobox 0.326646
PSENEN presenilin enhancer gamma secretase subunit 0.325916
CD79B CD79b molecule, immunoglobulin-associated beta 0.318999
IL1A interleukin 1, alpha 0.316819
IL6 interleukin 6 0.315366
C5AR2 complement component 5a receptor 2 0.313915
GLUL glutamate-ammonia ligase 0.30848
BAG6 BCL2-associated athanogene 6 0.302337
INA internexin neuronal intermediate filament protein, alpha 0.301976
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.301615
CD69 CD69 molecule 0.296571
MYH7 myosin, heavy chain 7, cardiac muscle, beta 0.295492
IL17A interleukin 17A 0.294413
DNAH8 dynein, axonemal, heavy chain 8 0.294053
CD47 CD47 molecule 0.293694
PLP1 proteolipid protein 1 0.293694
TAC1 tachykinin, precursor 1 0.291539
ADCY1 adenylate cyclase 1 (brain) 0.29118
ADCY3 adenylate cyclase 3 0.289744
F2R coagulation factor II (thrombin) receptor 0.288668
TOLLIP toll interacting protein 0.287235
AMT aminomethyltransferase 0.286519
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.286519
CCDC27 coiled-coil domain containing 27 0.276514
LIPE lipase, hormone-sensitive 0.271886
SEPT3 septin 3 0.268687
ADCY10 adenylate cyclase 10 (soluble) 0.267267
OLIG1 oligodendrocyte transcription factor 1 0.265494
HSF4 heat shock transcription factor 4 0.260184
ADSS adenylosuccinate synthase 0.259124
NPFF neuropeptide FF-amide peptide precursor 0.257711
ADRA1B adrenoceptor alpha 1B 0.254888
CD19 CD19 molecule 0.254536
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 0.253831
SUMF1 sulfatase modifying factor 1 0.252422
SAMM50 SAMM50 sorting and assembly machinery component 0.251718
HEXA hexosaminidase A (alpha polypeptide) 0.250311
ADCY9 adenylate cyclase 9 0.246799
SSTR2 somatostatin receptor 2 0.241546
NPR1 natriuretic peptide receptor 1 0.240847
GUCY2C guanylate cyclase 2C 0.240148
ALYREF Aly/REF export factor 0.237706
LTB lymphotoxin beta (TNF superfamily, member 3) 0.237357
ADCY6 adenylate cyclase 6 0.237357
ADCY5 adenylate cyclase 5 0.234573
RASD1 RAS, dexamethasone-induced 1 0.233878
POU3F2 POU class 3 homeobox 2 0.228333
BLVRB biliverdin reductase B 0.227297
TOX3 TOX high mobility group box family member 3 0.218374
MOGS mannosyl-oligosaccharide glucosidase 0.216672
PRKCZ protein kinase C, zeta 0.211261
ADRA1A adrenoceptor alpha 1A 0.205916
CKAP5 cytoskeleton associated protein 5 0.204923
DCPS decapping enzyme, scavenger 0.204263
CNR1 cannabinoid receptor 1 (brain) 0.20229
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.200331
CCL21 chemokine (C-C motif) ligand 21 0.200006
LIG3 ligase III, DNA, ATP-dependent 0.196459
CFP complement factor properdin 0.192971
ATOX1 antioxidant 1 copper chaperone 0.188632
ADCY8 adenylate cyclase 8 (brain) 0.187719
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 0.185612
IRAK3 interleukin-1 receptor-associated kinase 3 0.185313
CREM cAMP responsive element modulator 0.185016
RD3 retinal degeneration 3 0.182375
GCG glucagon 0.182375
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.182086
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.181798
CD86 CD86 molecule 0.180652
TFCP2 transcription factor CP2 0.177301
HP haptoglobin 0.175947
SAMHD1 SAM domain and HD domain 1 0.174354
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.173571
TNNT1 troponin T type 1 (skeletal, slow) 0.173571
INVS inversin 0.173571
HPR haptoglobin-related protein 0.171785
GRP gastrin-releasing peptide 0.171785
CPT2 carnitine palmitoyltransferase 2 0.167682
GRAP2 GRB2-related adaptor protein 2 0.166095
SEPT4 septin 4 0.165874
PRDM2 PR domain containing 2, with ZNF domain 0.165217
TUB tubby bipartite transcription factor 0.164149
ATG4C autophagy related 4C, cysteine peptidase 0.163729
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.163523
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.161716
TACR1 tachykinin receptor 1 0.161139
CPSF3L cleavage and polyadenylation specific factor 3-like 0.159124