peutz-jeghers syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_3852)
Similar Terms
Downloads & Tools

Genes

120 genes co-occuring with the disease peutz-jeghers syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
STK11 serine/threonine kinase 11 3.55446
STK11IP serine/threonine kinase 11 interacting protein 1.80652
STRADA STE20-related kinase adaptor alpha 1.70178
PTEN phosphatase and tensin homolog 1.51545
SBNO2 strawberry notch homolog 2 (Drosophila) 1.48955
CIRBP-AS1 CIRBP antisense RNA 1 1.43947
WDR6 WD repeat domain 6 1.41621
CAB39 calcium binding protein 39 1.40176
BRCA2 breast cancer 2, early onset 1.34635
PTPRH protein tyrosine phosphatase, receptor type, H 1.32934
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.25907
MIDN midnolin 1.17507
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.16606
BMPR1A bone morphogenetic protein receptor, type IA 1.12994
REEP6 receptor accessory protein 6 1.05303
EPB41L5 erythrocyte membrane protein band 4.1 like 5 1.05303
ZNF444 zinc finger protein 444 1.01554
SMAD4 SMAD family member 4 1.00161
TP53 tumor protein p53 0.9898
CAB39L calcium binding protein 39-like 0.978426
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.919261
NLRP11 NLR family, pyrin domain containing 11 0.897872
KRAS Kirsten rat sarcoma viral oncogene homolog 0.896641
NUAK1 NUAK family, SNF1-like kinase, 1 0.887208
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.886799
TSC2 tuberous sclerosis 2 0.876557
MUTYH mutY homolog 0.870006
BRCA1 breast cancer 1, early onset 0.843392
PALB2 partner and localizer of BRCA2 0.838066
CYTH2 cytohesin 2 0.822897
HRAS Harvey rat sarcoma viral oncogene homolog 0.806488
MUC6 mucin 6, oligomeric mucus/gel-forming 0.806488
BRSK1 BR serine/threonine kinase 1 0.804026
NLRP4 NLR family, pyrin domain containing 4 0.797052
USP39 ubiquitin specific peptidase 39 0.784755
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.780251
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 0.776568
NINL ninein-like 0.766351
EPN1 epsin 1 0.761047
CDC37 cell division cycle 37 0.744766
DIXDC1 DIX domain containing 1 0.737054
IFITM1 interferon induced transmembrane protein 1 0.697109
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 0.695905
TRAPPC10 trafficking protein particle complex 10 0.688692
NLRP5 NLR family, pyrin domain containing 5 0.686691
CDKN2A cyclin-dependent kinase inhibitor 2A 0.648928
C19ORF26 chromosome 19 open reading frame 26 0.646953
MARK4 MAP/microtubule affinity-regulating kinase 4 0.640645
EFNA2 ephrin-A2 0.623751
TSC1 tuberous sclerosis 1 0.619834
CALB2 calbindin 2 0.615921
U2AF2 U2 small nuclear RNA auxiliary factor 2 0.604591
AMPD3 adenosine monophosphate deaminase 3 0.592895
CHEK2 checkpoint kinase 2 0.581217
RHEB Ras homolog enriched in brain 0.57655
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 0.568775
LYPD1 LY6/PLAUR domain containing 1 0.562169
MYH1 myosin, heavy chain 1, skeletal muscle, adult 0.55945
MSH2 mutS homolog 2 0.556732
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 0.554403
MEIS2 Meis homeobox 2 0.553239
CIRBP cold inducible RNA binding protein 0.542379
MARK3 MAP/microtubule affinity-regulating kinase 3 0.538118
MARK1 MAP/microtubule affinity-regulating kinase 1 0.536957
PRSS1 protease, serine, 1 (trypsin 1) 0.521502
MARK2 MAP/microtubule affinity-regulating kinase 2 0.520346
F10 coagulation factor X 0.506123
SHKBP1 SH3KBP1 binding protein 1 0.491215
AURKC aurora kinase C 0.483985
PRKCG protein kinase C, gamma 0.475255
ATF5 activating transcription factor 5 0.468441
TGFB1 transforming growth factor, beta 1 0.465416
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.46466
WNT5B wingless-type MMTV integration site family, member 5B 0.442042
MLH1 mutL homolog 1 0.436402
MSH6 mutS homolog 6 0.432646
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 0.42664
DEFA5 defensin, alpha 5, Paneth cell-specific 0.419517
FZD2 frizzled class receptor 2 0.415398
INHA inhibin, alpha 0.412405
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.409414
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0.407172
TAGLN transgelin 0.385565
FNDC3A fibronectin type III domain containing 3A 0.382966
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.378885
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.371477
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.369628
PRSS3 protease, serine, 3 0.368518
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.361502
SNRPA small nuclear ribonucleoprotein polypeptide A 0.355972
PALLD palladin, cytoskeletal associated protein 0.353395
NEK2 NIMA-related kinase 2 0.337608
WNT11 wingless-type MMTV integration site family, member 11 0.333583
MEN1 multiple endocrine neoplasia I 0.325916
KLK10 kallikrein-related peptidase 10 0.311739
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.311739
SLK STE20-like kinase 0.296931
FAXDC2 fatty acid hydroxylase domain containing 2 0.284728
RAD51C RAD51 paralog C 0.264077
HIST3H2BB histone cluster 3, H2bb 0.257005
HIST2H2BF histone cluster 2, H2bf 0.255594
HIST1H2BH histone cluster 1, H2bh 0.253127
HIST1H2BA histone cluster 1, H2ba 0.253127
HIST1H2BD histone cluster 1, H2bd 0.253127
NKX2-5 NK2 homeobox 5 0.249257
CCND1 cyclin D1 0.240497
HIST1H2BC histone cluster 1, H2bc 0.23945
HIST1H2BF histone cluster 1, H2bf 0.23945
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.225573
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.209918
MCF2 MCF.2 cell line derived transforming sequence 0.20658
GNAS GNAS complex locus 0.201962
PTER phosphotriesterase related 0.195501
PGC progastricsin (pepsinogen C) 0.191097
GATA6 GATA binding protein 6 0.180652
WIF1 WNT inhibitory factor 1 0.174093
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.170054
SIK1 salt-inducible kinase 1 0.163729
RPTOR regulatory associated protein of MTOR, complex 1 0.163111
ATM ATM serine/threonine kinase 0.158778