phagocytosis, engulfment Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis. (Gene Ontology, GO_0006911)
External Link http://amigo.geneontology.org/amigo/term/GO_0006911
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Genes

31 genes participating in the phagocytosis, engulfment biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ADGRB1 adhesion G protein-coupled receptor B1
AIF1 allograft inflammatory factor 1
ARHGAP12 Rho GTPase activating protein 12
ARHGAP25 Rho GTPase activating protein 25
BIN2 bridging integrator 2
CD36 CD36 molecule (thrombospondin receptor)
CDC42 cell division cycle 42
DOCK1 dedicator of cytokinesis 1
ELMO1 engulfment and cell motility 1
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
GSN gelsolin
GULP1 GULP, engulfment adaptor PTB domain containing 1
HAVCR1 hepatitis A virus cellular receptor 1
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
MARCO macrophage receptor with collagenous structure
MEGF10 multiple EGF-like-domains 10
MSR1 macrophage scavenger receptor 1
MYH9 myosin, heavy chain 9, non-muscle
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
SH3BP1 SH3-domain binding protein 1
THBS1 thrombospondin 1
TIMD4 T-cell immunoglobulin and mucin domain containing 4
VAMP7 vesicle-associated membrane protein 7
XKR4 XK, Kell blood group complex subunit-related family, member 4
XKR5 XK, Kell blood group complex subunit-related family, member 5
XKR6 XK, Kell blood group complex subunit-related family, member 6
XKR7 XK, Kell blood group complex subunit-related family, member 7
XKR8 XK, Kell blood group complex subunit-related family, member 8
XKR9 XK, Kell blood group complex subunit-related family, member 9