phagocytosis Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description An endocytosis process that results in the engulfment of external particulate material by phagocytes. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles. (Gene Ontology, GO_0006909)
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Genes

202 genes co-occuring with the biological term phagocytosis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACKR3 atypical chemokine receptor 3
ADGRB1 adhesion G protein-coupled receptor B1
ADIPOQ adiponectin, C1Q and collagen domain containing
AFP alpha-fetoprotein
AGER advanced glycosylation end product-specific receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ANXA1 annexin A1
ANXA2 annexin A2
AOX1 aldehyde oxidase 1
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APCS amyloid P component, serum
APOD apolipoprotein D
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
ARF1 ADP-ribosylation factor 1
ARF6 ADP-ribosylation factor 6
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BCAR1 breast cancer anti-estrogen resistance 1
BIN2 bridging integrator 2
C2 complement component 2
C3 complement component 3
C4B complement component 4B (Chido blood group)
C4BPB complement component 4 binding protein, beta
C5 complement component 5
C5AR1 complement component 5a receptor 1
CALR calreticulin
CAMK1D calcium/calmodulin-dependent protein kinase ID
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD14 CD14 molecule
CD209 CD209 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD47 CD47 molecule
CDC42 cell division cycle 42
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CERK ceramide kinase
CFH complement factor H
CIITA class II, major histocompatibility complex, transactivator
CLCN3 chloride channel, voltage-sensitive 3
CLEC10A C-type lectin domain family 10, member A
CLEC11A C-type lectin domain family 11, member A
CLEC7A C-type lectin domain family 7, member A
COLEC12 collectin sub-family member 12
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRP C-reactive protein, pentraxin-related
CSF3 colony stimulating factor 3 (granulocyte)
CSF3R colony stimulating factor 3 receptor (granulocyte)
CSK c-src tyrosine kinase
CTSK cathepsin K
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
CYBB cytochrome b-245, beta polypeptide
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
DCN decorin
DYSF dysferlin
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB2 erb-b2 receptor tyrosine kinase 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
FASLG Fas ligand (TNF superfamily, member 6)
FCAR Fc fragment of IgA receptor
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FGFR2 fibroblast growth factor receptor 2
FGG fibrinogen gamma chain
FMNL1 formin-like 1
GAS6 growth arrest-specific 6
GRB14 growth factor receptor-bound protein 14
GSR glutathione reductase
GULP1 GULP, engulfment adaptor PTB domain containing 1
HMGB1 high mobility group box 1
HRG histidine-rich glycoprotein
ICAM3 intercellular adhesion molecule 3
IFNG interferon, gamma
IL10 interleukin 10
IL12A interleukin 12A
IL17A interleukin 17A
IL1B interleukin 1, beta
INHBA inhibin, beta A
INPPL1 inositol polyphosphate phosphatase-like 1
IQSEC1 IQ motif and Sec7 domain 1
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB5 integrin, beta 5
JMJD6 jumonji domain containing 6
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
LBP lipopolysaccharide binding protein
LGALS3 lectin, galactoside-binding, soluble, 3
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LRP1 low density lipoprotein receptor-related protein 1
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MARCO macrophage receptor with collagenous structure
MBL2 mannose-binding lectin (protein C) 2, soluble
MERTK MER proto-oncogene, tyrosine kinase
MFGE8 milk fat globule-EGF factor 8 protein
MIR142 microRNA 142
MIR155 microRNA 155
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MRC1 mannose receptor, C type 1
MSR1 macrophage scavenger receptor 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYH9 myosin, heavy chain 9, non-muscle
NCF1 neutrophil cytosolic factor 1
NCF4 neutrophil cytosolic factor 4, 40kDa
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NOX1 NADPH oxidase 1
ORAI1 ORAI calcium release-activated calcium modulator 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PBX1 pre-B-cell leukemia homeobox 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKNOX1 PBX/knotted 1 homeobox 1
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAUR plasminogen activator, urokinase receptor
PLCG1 phospholipase C, gamma 1
PPARG peroxisome proliferator-activated receptor gamma
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROS1 protein S (alpha)
PRTN3 proteinase 3
PTEN phosphatase and tensin homolog
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAB27A RAB27A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAP1A RAP1A, member of RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RGCC regulator of cell cycle
RHEB Ras homolog enriched in brain
RHOB ras homolog family member B
RXRA retinoid X receptor, alpha
S100A10 S100 calcium binding protein A10
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCN5A sodium channel, voltage gated, type V alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPA1 surfactant protein A1
SFTPD surfactant protein D
SIGLEC11 sialic acid binding Ig-like lectin 11
SIGLEC5 sialic acid binding Ig-like lectin 5
SIRPA signal-regulatory protein alpha
SIRPB1 signal-regulatory protein beta 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX3 sorting nexin 3
SOD3 superoxide dismutase 3, extracellular
SPN sialophorin
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
STAB1 stabilin 1
STAB2 stabilin 2
STIM1 stromal interaction molecule 1
STX7 syntaxin 7
SYK spleen tyrosine kinase
SYT2 synaptotagmin II
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TP53 tumor protein p53
TREM2 triggering receptor expressed on myeloid cells 2
TREX1 three prime repair exonuclease 1
TUB tubby bipartite transcription factor
TULP1 tubby like protein 1
TXN thioredoxin
VIPR2 vasoactive intestinal peptide receptor 2
VNN2 vanin 2
WAS Wiskott-Aldrich syndrome
WASL Wiskott-Aldrich syndrome-like
XKR8 XK, Kell blood group complex subunit-related family, member 8