phenazone-1489 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the phenazone-1489 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMT aminomethyltransferase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BIN1 bridging integrator 1
BMP1 bone morphogenetic protein 1
C5AR2 complement component 5a receptor 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP104 centrosomal protein 104kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRM3 cholinergic receptor, muscarinic 3
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCF1 cardiotrophin-like cytokine factor 1
COL5A1 collagen, type V, alpha 1
CRTC1 CREB regulated transcription coactivator 1
CRYGD crystallin, gamma D
CUL7 cullin 7
DCTN1 dynactin 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DMPK dystrophia myotonica-protein kinase
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOCK6 dedicator of cytokinesis 6
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DZIP3 DAZ interacting zinc finger protein 3
EDNRA endothelin receptor type A
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EMID1 EMI domain containing 1
FAM169A family with sequence similarity 169, member A
FAM174B family with sequence similarity 174, member B
FGF2 fibroblast growth factor 2 (basic)
FGF6 fibroblast growth factor 6
FGL2 fibrinogen-like 2
GEMIN8 gem (nuclear organelle) associated protein 8
GOLGA2 golgin A2
GP5 glycoprotein V (platelet)
GPATCH3 G patch domain containing 3
GPR182 G protein-coupled receptor 182
GSPT1 G1 to S phase transition 1
HOXA10 homeobox A10
HOXC10 homeobox C10
HP haptoglobin
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IPO5 importin 5
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAM3 junctional adhesion molecule 3
KCNK10 potassium channel, two pore domain subfamily K, member 10
KIAA0754 KIAA0754
LMAN1 lectin, mannose-binding, 1
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LYPD1 LY6/PLAUR domain containing 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MERTK MER proto-oncogene, tyrosine kinase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MOBP myelin-associated oligodendrocyte basic protein
MRPL41 mitochondrial ribosomal protein L41
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOAZFP nucleolar atypical zinc finger
OVOL2 ovo-like zinc finger 2
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
POU2F2 POU class 2 homeobox 2
RER1 retention in endoplasmic reticulum sorting receptor 1
RYR2 ryanodine receptor 2 (cardiac)
SCUBE3 signal peptide, CUB domain, EGF-like 3
SF1 splicing factor 1
SH3BGR SH3 domain binding glutamate-rich protein
SH3BP2 SH3-domain binding protein 2
SIRPA signal-regulatory protein alpha
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SOX15 SRY (sex determining region Y)-box 15
SRI sorcin
SSPN sarcospan
STARD8 StAR-related lipid transfer (START) domain containing 8
STK17A serine/threonine kinase 17a
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TH tyrosine hydroxylase
TMC7 transmembrane channel-like 7
TMOD1 tropomodulin 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNXB tenascin XB
TREX1 three prime repair exonuclease 1
TRIM14 tripartite motif containing 14
TTC38 tetratricopeptide repeat domain 38
UBXN6 UBX domain protein 6
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
WWP2 WW domain containing E3 ubiquitin protein ligase 2
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZDHHC11 zinc finger, DHHC-type containing 11
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF324 zinc finger protein 324
ZNF419 zinc finger protein 419
ZNF446 zinc finger protein 446
ZNF506 zinc finger protein 506
ZNF516 zinc finger protein 516
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADGRE5 adhesion G protein-coupled receptor E5
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARSB arylsulfatase B
ASCC2 activating signal cointegrator 1 complex subunit 2
BCL9 B-cell CLL/lymphoma 9
BFSP1 beaded filament structural protein 1, filensin
BMP4 bone morphogenetic protein 4
CAPN15 calpain 15
CCDC170 coiled-coil domain containing 170
CCP110 centriolar coiled coil protein 110kDa
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHKB choline kinase beta
CHML choroideremia-like (Rab escort protein 2)
CHPF chondroitin polymerizing factor
CHST10 carbohydrate sulfotransferase 10
CIR1 corepressor interacting with RBPJ, 1
CLCN5 chloride channel, voltage-sensitive 5
CLSTN1 calsyntenin 1
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRYBG3 beta-gamma crystallin domain containing 3
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DOC2A double C2-like domains, alpha
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
FADS2 fatty acid desaturase 2
FAM131A family with sequence similarity 131, member A
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGD1 FYVE, RhoGEF and PH domain containing 1
FKBP10 FK506 binding protein 10, 65 kDa
FKBP8 FK506 binding protein 8, 38kDa
FLJ22184
FOXN2 forkhead box N2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
FURIN furin (paired basic amino acid cleaving enzyme)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRTP1 growth hormone regulated TBC protein 1
HIST1H2AI histone cluster 1, H2ai
HOXC13 homeobox C13
HSPA1L heat shock 70kDa protein 1-like
INPP5J inositol polyphosphate-5-phosphatase J
IRF6 interferon regulatory factor 6
LIN7A lin-7 homolog A (C. elegans)
LINC00339 long intergenic non-protein coding RNA 339
LRRC8E leucine rich repeat containing 8 family, member E
LZTFL1 leucine zipper transcription factor-like 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGEF1 melanoma antigen family F1
MAST3 microtubule associated serine/threonine kinase 3
MFSD11 major facilitator superfamily domain containing 11
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
OLFML2A olfactomedin-like 2A
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCSK7 proprotein convertase subtilisin/kexin type 7
PLA2G15 phospholipase A2, group XV
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PNPLA6 patatin-like phospholipase domain containing 6
POLH polymerase (DNA directed), eta
PRPH peripherin
PTPRE protein tyrosine phosphatase, receptor type, E
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF2 ring finger protein 2
RPH3AL rabphilin 3A-like (without C2 domains)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH2B3 SH2B adaptor protein 3
SLC12A9 solute carrier family 12, member 9
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLMO1 slowmo homolog 1 (Drosophila)
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPRYD7 SPRY domain containing 7
SRD5A3 steroid 5 alpha-reductase 3
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TBX19 T-box 19
TMEM104 transmembrane protein 104
TRAIP TRAF interacting protein
TSPAN5 tetraspanin 5
TSPYL2 TSPY-like 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VEGFB vascular endothelial growth factor B
VWA1 von Willebrand factor A domain containing 1
WLS wntless Wnt ligand secretion mediator
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF205 zinc finger protein 205
ZNF271P zinc finger protein 271, pseudogene
ZNF423 zinc finger protein 423
ZNF442 zinc finger protein 442
ZNF557 zinc finger protein 557
ZSCAN31 zinc finger and SCAN domain containing 31