phenazone-1989 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the phenazone-1989 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AACS acetoacetyl-CoA synthetase
ACRV1 acrosomal vesicle protein 1
ACSL4 acyl-CoA synthetase long-chain family member 4
ADM2 adrenomedullin 2
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ARHGAP10 Rho GTPase activating protein 10
ATP10B ATPase, class V, type 10B
AVL9 AVL9 homolog (S. cerevisiase)
AVPR1B arginine vasopressin receptor 1B
AXIN1 axin 1
BBS1 Bardet-Biedl syndrome 1
BCLAF1 BCL2-associated transcription factor 1
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
C21ORF2 chromosome 21 open reading frame 2
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CAMKV CaM kinase-like vesicle-associated
CD101 CD101 molecule
CD82 CD82 molecule
CDC14B cell division cycle 14B
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CIITA class II, major histocompatibility complex, transactivator
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CPOX coproporphyrinogen oxidase
CTNNBIP1 catenin, beta interacting protein 1
CTSZ cathepsin Z
DDR1 discoidin domain receptor tyrosine kinase 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPY19L1 dpy-19-like 1 (C. elegans)
EFNA5 ephrin-A5
EIF4E eukaryotic translation initiation factor 4E
FAM106A family with sequence similarity 106, member A
FAM86C1 family with sequence similarity 86, member C1
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGFR1 fibroblast growth factor receptor 1
FSCN3 fascin actin-bundling protein 3, testicular
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPX2 glutathione peroxidase 2
HIRA histone cell cycle regulator
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM4B lysine (K)-specific demethylase 4B
KIAA0586 KIAA0586
KIF3C kinesin family member 3C
KIFC1 kinesin family member C1
KRCC1 lysine-rich coiled-coil 1
KRIT1 KRIT1, ankyrin repeat containing
LARP4 La ribonucleoprotein domain family, member 4
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
MAST2 microtubule associated serine/threonine kinase 2
MBD3 methyl-CpG binding domain protein 3
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
METTL7A methyltransferase like 7A
MFSD7 major facilitator superfamily domain containing 7
MST1 macrophage stimulating 1
MT4 metallothionein 4
MUC2 mucin 2, oligomeric mucus/gel-forming
MYL10 myosin, light chain 10, regulatory
MYT1 myelin transcription factor 1
NIPAL2 NIPA-like domain containing 2
PARP16 poly (ADP-ribose) polymerase family, member 16
PAX1 paired box 1
PCIF1 PDX1 C-terminal inhibiting factor 1
PGPEP1 pyroglutamyl-peptidase I
PHACTR2 phosphatase and actin regulator 2
PIAS3 protein inhibitor of activated STAT, 3
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
PPT2 palmitoyl-protein thioesterase 2
PSG4 pregnancy specific beta-1-glycoprotein 4
PTER phosphotriesterase related
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB6B RAB6B, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RAD23B RAD23 homolog B (S. cerevisiae)
RHBDD3 rhomboid domain containing 3
RPS11 ribosomal protein S11
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RRBP1 ribosome binding protein 1
SETD4 SET domain containing 4
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLC25A44 solute carrier family 25, member 44
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPDEF SAM pointed domain containing ETS transcription factor
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SYNGR1 synaptogyrin 1
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TET3 tet methylcytosine dioxygenase 3
TRAPPC10 trafficking protein particle complex 10
TRD T cell receptor delta locus
TRIM22 tripartite motif containing 22
USF2 upstream transcription factor 2, c-fos interacting
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
WDR44 WD repeat domain 44
ZNF426 zinc finger protein 426

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
AATF apoptosis antagonizing transcription factor
ABHD11 abhydrolase domain containing 11
AGPS alkylglycerone phosphate synthase
ANXA2P2 annexin A2 pseudogene 2
APOC2 apolipoprotein C-II
ATF3 activating transcription factor 3
ATG9A autophagy related 9A
ATXN2 ataxin 2
B3GNT1
BATF3 basic leucine zipper transcription factor, ATF-like 3
BBC3 BCL2 binding component 3
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
C19ORF24 chromosome 19 open reading frame 24
CCL2 chemokine (C-C motif) ligand 2
CEP85 centrosomal protein 85kDa
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLDN15 claudin 15
CLDND1 claudin domain containing 1
COMMD10 COMM domain containing 10
COPS3 COP9 signalosome subunit 3
CRELD2 cysteine-rich with EGF-like domains 2
CRY1 cryptochrome circadian clock 1
CYB5R4 cytochrome b5 reductase 4
DCTN4 dynactin 4 (p62)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
ERMP1 endoplasmic reticulum metallopeptidase 1
EXOSC9 exosome component 9
GDE1 glycerophosphodiester phosphodiesterase 1
GMEB1 glucocorticoid modulatory element binding protein 1
GOLGA8B golgin A8 family, member B
GSR glutathione reductase
HACD3 3-hydroxyacyl-CoA dehydratase 3
HARS histidyl-tRNA synthetase
HIST1H1C histone cluster 1, H1c
HIST1H1E histone cluster 1, H1e
HIST1H2BE histone cluster 1, H2be
HMGB3P1 high mobility group box 3 pseudogene 1
HNRNPF heterogeneous nuclear ribonucleoprotein F
INF2 inverted formin, FH2 and WH2 domain containing
INO80D INO80 complex subunit D
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA10 integrin, alpha 10
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KIAA0196 KIAA0196
KIZ kizuna centrosomal protein
LMAN2L lectin, mannose-binding 2-like
LOC100127972 uncharacterized LOC100127972
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPPR3 lipid phosphate phosphatase-related protein type 3
LRRC42 leucine rich repeat containing 42
MAGOHB mago-nashi homolog B (Drosophila)
MAPKBP1 mitogen-activated protein kinase binding protein 1
MARCKSL1 MARCKS-like 1
MECR mitochondrial trans-2-enoyl-CoA reductase
MITF microphthalmia-associated transcription factor
MTG1 mitochondrial ribosome-associated GTPase 1
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NEK11 NIMA-related kinase 11
NFE2 nuclear factor, erythroid 2
NHEJ1 nonhomologous end-joining factor 1
NT5C 5', 3'-nucleotidase, cytosolic
PAAF1 proteasomal ATPase-associated factor 1
PCDHGB5 protocadherin gamma subfamily B, 5
PITRM1 pitrilysin metallopeptidase 1
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PMVK phosphomevalonate kinase
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
PRCP prolylcarboxypeptidase (angiotensinase C)
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
RECQL4 RecQ protein-like 4
RNF146 ring finger protein 146
RSL24D1 ribosomal L24 domain containing 1
SDCCAG3 serologically defined colon cancer antigen 3
SEPW1 selenoprotein W, 1
SIRT2 sirtuin 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SPI1 Spi-1 proto-oncogene
STAU2 staufen double-stranded RNA binding protein 2
TCTN2 tectonic family member 2
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM127 transmembrane protein 127
TMEM184B transmembrane protein 184B
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
USP20 ubiquitin specific peptidase 20
USP39 ubiquitin specific peptidase 39
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR46 WD repeat domain 46
YEATS4 YEATS domain containing 4
ZNF211 zinc finger protein 211
ZNF408 zinc finger protein 408