phenazopyridine-5758 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the phenazopyridine-5758 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AGFG2 ArfGAP with FG repeats 2
AKR1C1 aldo-keto reductase family 1, member C1
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APOE apolipoprotein E
APOM apolipoprotein M
ARPIN actin-related protein 2/3 complex inhibitor
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BBC3 BCL2 binding component 3
C14ORF1 chromosome 14 open reading frame 1
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCDC57 coiled-coil domain containing 57
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD79A CD79a molecule, immunoglobulin-associated alpha
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHAT choline O-acetyltransferase
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CLCN6 chloride channel, voltage-sensitive 6
COL9A3 collagen, type IX, alpha 3
CREM cAMP responsive element modulator
CRHR2 corticotropin releasing hormone receptor 2
CSF1 colony stimulating factor 1 (macrophage)
CTSS cathepsin S
DDIT3 DNA-damage-inducible transcript 3
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK9 dedicator of cytokinesis 9
EDNRB endothelin receptor type B
EFNA3 ephrin-A3
F9 coagulation factor IX
FCMR Fc fragment of IgM receptor
GABARAPL1 GABA(A) receptor-associated protein like 1
GK glycerol kinase
GRTP1 growth hormone regulated TBC protein 1
GTDC1 glycosyltransferase-like domain containing 1
HAO2 hydroxyacid oxidase 2 (long chain)
HIST1H4B histone cluster 1, H4b
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMOX1 heme oxygenase 1
IGL immunoglobulin lambda locus
IL2RG interleukin 2 receptor, gamma
INSIG1 insulin induced gene 1
KHK ketohexokinase (fructokinase)
KLF4 Kruppel-like factor 4 (gut)
KRT38 keratin 38, type I
KRT86 keratin 86, type II
LIPE lipase, hormone-sensitive
LRRN3 leucine rich repeat neuronal 3
MTMR8 myotubularin related protein 8
NDNF neuron-derived neurotrophic factor
NMBR neuromedin B receptor
NPC1 Niemann-Pick disease, type C1
PASK PAS domain containing serine/threonine kinase
PAWR PRKC, apoptosis, WT1, regulator
PBX2 pre-B-cell leukemia homeobox 2
PCDHGA3 protocadherin gamma subfamily A, 3
PECAM1 platelet/endothelial cell adhesion molecule 1
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PMFBP1 polyamine modulated factor 1 binding protein 1
POMT2 protein-O-mannosyltransferase 2
PRAMEF12 PRAME family member 12
PRDM2 PR domain containing 2, with ZNF domain
PRKG2 protein kinase, cGMP-dependent, type II
PRR5L proline rich 5 like
PRSS22 protease, serine, 22
PRX periaxin
PVR poliovirus receptor
RASAL2 RAS protein activator like 2
RPL10 ribosomal protein L10
SATB2 SATB homeobox 2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SIL1 SIL1 nucleotide exchange factor
SIRAL2 SIR2 antiphage like 2
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SMC1A structural maintenance of chromosomes 1A
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STRA6 stimulated by retinoic acid 6
STX3 syntaxin 3
SYNGR3 synaptogyrin 3
SYT12 synaptotagmin XII
SYT17 synaptotagmin XVII
TAL1 T-cell acute lymphocytic leukemia 1
TFEB transcription factor EB
TGFA transforming growth factor, alpha
TMEM19 transmembrane protein 19
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TP53I11 tumor protein p53 inducible protein 11
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VWA5A von Willebrand factor A domain containing 5A
ZIC4 Zic family member 4
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
AEN apoptosis enhancing nuclease
AFAP1 actin filament associated protein 1
ALPK1 alpha-kinase 1
AMDHD2 amidohydrolase domain containing 2
ANXA10 annexin A10
APOL6 apolipoprotein L, 6
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAHD1 bromo adjacent homology domain containing 1
C17ORF53 chromosome 17 open reading frame 53
C17ORF80 chromosome 17 open reading frame 80
C9ORF40 chromosome 9 open reading frame 40
CCDC9 coiled-coil domain containing 9
CDON cell adhesion associated, oncogene regulated
CENPO centromere protein O
CNGB3 cyclic nucleotide gated channel beta 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DBF4B DBF4 zinc finger B
DBR1 debranching RNA lariats 1
DENND2D DENN/MADD domain containing 2D
DNAH7 dynein, axonemal, heavy chain 7
FAM105A family with sequence similarity 105, member A
FAM184A family with sequence similarity 184, member A
FAM222B family with sequence similarity 222, member B
FER fer (fps/fes related) tyrosine kinase
FGL1 fibrinogen-like 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GDAP1 ganglioside induced differentiation associated protein 1
GHR growth hormone receptor
GLCE glucuronic acid epimerase
GNL1 guanine nucleotide binding protein-like 1
GRB7 growth factor receptor-bound protein 7
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HIST1H3B histone cluster 1, H3b
HOXA4 homeobox A4
IL12A interleukin 12A
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IMPACT impact RWD domain protein
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KIAA0754 KIAA0754
KIAA1107 KIAA1107
KLF3 Kruppel-like factor 3 (basic)
KRT9 keratin 9, type I
LMCD1 LIM and cysteine-rich domains 1
LNPEP leucyl/cystinyl aminopeptidase
LRP3 low density lipoprotein receptor-related protein 3
MAP1S microtubule-associated protein 1S
MDFI MyoD family inhibitor
MECR mitochondrial trans-2-enoyl-CoA reductase
METTL1 methyltransferase like 1
MFGE8 milk fat globule-EGF factor 8 protein
MOB3B MOB kinase activator 3B
MYLIP myosin regulatory light chain interacting protein
NDE1 nudE neurodevelopment protein 1
NDP Norrie disease (pseudoglioma)
NME5 NME/NM23 family member 5
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
OSMR oncostatin M receptor
PC pyruvate carboxylase
PCOLCE procollagen C-endopeptidase enhancer
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAC8 placenta-specific 8
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PRMT7 protein arginine methyltransferase 7
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RHOBTB2 Rho-related BTB domain containing 2
RPL13P5 ribosomal protein L13 pseudogene 5
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
S100A3 S100 calcium binding protein A3
SCAI suppressor of cancer cell invasion
SCN10A sodium channel, voltage gated, type X alpha subunit
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SH2D2A SH2 domain containing 2A
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLITRK5 SLIT and NTRK-like family, member 5
SPRYD7 SPRY domain containing 7
SUGCT succinyl-CoA:glutarate-CoA transferase
SYTL2 synaptotagmin-like 2
TAGLN transgelin
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TCEAL2 transcription elongation factor A (SII)-like 2
TENM1 teneurin transmembrane protein 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TWISTNB TWIST neighbor
USP18 ubiquitin specific peptidase 18
VEZT vezatin, adherens junctions transmembrane protein
ZMAT5 zinc finger, matrin-type 5
ZNF768 zinc finger protein 768
ZNF862 zinc finger protein 862
ZNHIT2 zinc finger, HIT-type containing 2