phenazopyridine-6234 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the phenazopyridine-6234 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AK1 adenylate kinase 1
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AOX1 aldehyde oxidase 1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ATP7B ATPase, Cu++ transporting, beta polypeptide
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BTBD7 BTB (POZ) domain containing 7
C14ORF79 chromosome 14 open reading frame 79
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAMKMT calmodulin-lysine N-methyltransferase
CASP1 caspase 1, apoptosis-related cysteine peptidase
CBX8 chromobox homolog 8
CCL27 chemokine (C-C motif) ligand 27
CCNG2 cyclin G2
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CIDEB cell death-inducing DFFA-like effector b
COL5A1 collagen, type V, alpha 1
COMMD4 COMM domain containing 4
CRTC1 CREB regulated transcription coactivator 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
CXCR2 chemokine (C-X-C motif) receptor 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DACH1 dachshund family transcription factor 1
DGAT1 diacylglycerol O-acyltransferase 1
DMPK dystrophia myotonica-protein kinase
DUSP10 dual specificity phosphatase 10
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FLCN folliculin
HIST1H2AJ histone cluster 1, H2aj
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXC8 homeobox C8
IDI2-AS1 IDI2 antisense RNA 1
IFFO1 intermediate filament family orphan 1
IGSF1 immunoglobulin superfamily, member 1
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL11 interleukin 11
INHBA inhibin, beta A
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INSIG1 insulin induced gene 1
IRS2 insulin receptor substrate 2
KIAA0319L KIAA0319-like
KLHL24 kelch-like family member 24
LINC00339 long intergenic non-protein coding RNA 339
LMO2 LIM domain only 2 (rhombotin-like 1)
LPL lipoprotein lipase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MIIP migration and invasion inhibitory protein
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP3 matrix metallopeptidase 3
MTMR3 myotubularin related protein 3
MYT1 myelin transcription factor 1
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NEK11 NIMA-related kinase 11
NF2 neurofibromin 2 (merlin)
NIPAL3 NIPA-like domain containing 3
NOS1 nitric oxide synthase 1 (neuronal)
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PADI1 peptidyl arginine deiminase, type I
PAPPA2 pappalysin 2
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDGFA platelet-derived growth factor alpha polypeptide
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLAA phospholipase A2-activating protein
PODXL2 podocalyxin-like 2
POGZ pogo transposable element with ZNF domain
PRPF18 pre-mRNA processing factor 18
RLN1 relaxin 1
RNF24 ring finger protein 24
RPGR retinitis pigmentosa GTPase regulator
SAPCD1 suppressor APC domain containing 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIPA1L3 signal-induced proliferation-associated 1 like 3
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRPX sushi-repeat containing protein, X-linked
STC1 stanniocalcin 1
STRA6 stimulated by retinoic acid 6
SUGP1 SURP and G patch domain containing 1
TCTA T-cell leukemia translocation altered
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TFE3 transcription factor binding to IGHM enhancer 3
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM259 transmembrane protein 259
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TREX1 three prime repair exonuclease 1
UBE3A ubiquitin protein ligase E3A
UNC13A unc-13 homolog A (C. elegans)
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZFPL1 zinc finger protein-like 1
ZNF250 zinc finger protein 250
ZNF589 zinc finger protein 589
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ANKRD36 ankyrin repeat domain 36
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGAP11A Rho GTPase activating protein 11A
ARMC6 armadillo repeat containing 6
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF3 activating transcription factor 3
AZI2 5-azacytidine induced 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BORA bora, aurora kinase A activator
C10ORF88 chromosome 10 open reading frame 88
C12ORF4 chromosome 12 open reading frame 4
C4ORF29 chromosome 4 open reading frame 29
CHMP6 charged multivesicular body protein 6
CHMP7 charged multivesicular body protein 7
CLASP1 cytoplasmic linker associated protein 1
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ERO1L ERO1-like (S. cerevisiae)
FAM222B family with sequence similarity 222, member B
FOXC1 forkhead box C1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FPGS folylpolyglutamate synthase
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GFOD1 glucose-fructose oxidoreductase domain containing 1
GHR growth hormone receptor
GLI3 GLI family zinc finger 3
GMEB1 glucocorticoid modulatory element binding protein 1
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GSTT1 glutathione S-transferase theta 1
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF2I general transcription factor IIi
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H1D histone cluster 1, H1d
ICE2 interactor of little elongation complex ELL subunit 2
IMPACT impact RWD domain protein
INO80D INO80 complex subunit D
IPP intracisternal A particle-promoted polypeptide
IRF7 interferon regulatory factor 7
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCTD20 potassium channel tetramerization domain containing 20
KDM5C lysine (K)-specific demethylase 5C
KIFC1 kinesin family member C1
KRBOX4 KRAB box domain containing 4
KRT13 keratin 13, type I
LAMA5 laminin, alpha 5
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LMNB1 lamin B1
LYPD1 LY6/PLAUR domain containing 1
MITF microphthalmia-associated transcription factor
MMD monocyte to macrophage differentiation-associated
MORC3 MORC family CW-type zinc finger 3
MSL1 male-specific lethal 1 homolog (Drosophila)
MYL5 myosin, light chain 5, regulatory
NCAM2 neural cell adhesion molecule 2
NEIL3 nei endonuclease VIII-like 3 (E. coli)
OGFRL1 opioid growth factor receptor-like 1
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PDZRN3 PDZ domain containing ring finger 3
PEX26 peroxisomal biogenesis factor 26
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLA2G15 phospholipase A2, group XV
PMP22 peripheral myelin protein 22
POR P450 (cytochrome) oxidoreductase
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PYGB phosphorylase, glycogen; brain
RAB23 RAB23, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIC8B RIC8 guanine nucleotide exchange factor B
RINT1 RAD50 interactor 1
RNF126P1 ring finger protein 126 pseudogene 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SHPK sedoheptulokinase
SLC16A6 solute carrier family 16, member 6
STAG3 stromal antigen 3
STARD13 StAR-related lipid transfer (START) domain containing 13
TFB1M transcription factor B1, mitochondrial
TPST2 tyrosylprotein sulfotransferase 2
TRAPPC6A trafficking protein particle complex 6A
TSPAN14 tetraspanin 14
TSPAN5 tetraspanin 5
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
WWC2 WW and C2 domain containing 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBED1 zinc finger, BED-type containing 1
ZBTB3 zinc finger and BTB domain containing 3
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF106 zinc finger protein 106
ZNF180 zinc finger protein 180
ZNF226 zinc finger protein 226
ZNF83 zinc finger protein 83
ZNHIT2 zinc finger, HIT-type containing 2