phenelzine-2319 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the phenelzine-2319 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADRA1A adrenoceptor alpha 1A
AGFG2 ArfGAP with FG repeats 2
AHNAK2 AHNAK nucleoprotein 2
AIM2 absent in melanoma 2
AKAP7 A kinase (PRKA) anchor protein 7
AKR1C1 aldo-keto reductase family 1, member C1
AMPH amphiphysin
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARSE arylsulfatase E (chondrodysplasia punctata 1)
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BHLHE40 basic helix-loop-helix family, member e40
C19ORF66 chromosome 19 open reading frame 66
C1ORF68 chromosome 1 open reading frame 68
C1ORF95 chromosome 1 open reading frame 95
CCDC40 coiled-coil domain containing 40
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLIC5 chloride intracellular channel 5
CNR2 cannabinoid receptor 2 (macrophage)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
CYTH4 cytohesin 4
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DNASE2B deoxyribonuclease II beta
ELOVL5 ELOVL fatty acid elongase 5
EMP1 epithelial membrane protein 1
EPHB1 EPH receptor B1
EPOR erythropoietin receptor
ETV7 ets variant 7
EVI2B ecotropic viral integration site 2B
EXOSC1 exosome component 1
FAIM2 Fas apoptotic inhibitory molecule 2
FANCA Fanconi anemia, complementation group A
FBN1 fibrillin 1
FMO6P flavin containing monooxygenase 6 pseudogene
FOXO4 forkhead box O4
GLB1L galactosidase, beta 1-like
GRIP2 glutamate receptor interacting protein 2
GYG2 glycogenin 2
HCRTR2 hypocretin (orexin) receptor 2
HDAC5 histone deacetylase 5
HFE hemochromatosis
HIF3A hypoxia inducible factor 3, alpha subunit
HNF1B HNF1 homeobox B
HNF4A hepatocyte nuclear factor 4, alpha
HOXA4 homeobox A4
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
IHH indian hedgehog
INE1 inactivation escape 1 (non-protein coding)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
LBP lipopolysaccharide binding protein
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LTBP2 latent transforming growth factor beta binding protein 2
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MED25 mediator complex subunit 25
MLN motilin
MMP11 matrix metallopeptidase 11
NAT6 N-acetyltransferase 6 (GCN5-related)
NEUROD4 neuronal differentiation 4
ONECUT2 one cut homeobox 2
OR1A1 olfactory receptor, family 1, subfamily A, member 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PARVA parvin, alpha
PAX2 paired box 2
POU4F1 POU class 4 homeobox 1
PRKCA protein kinase C, alpha
PRLR prolactin receptor
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTK2B protein tyrosine kinase 2 beta
PWAR5 Prader Willi/Angelman region RNA 5
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBMS2 RNA binding motif, single stranded interacting protein 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SAMD4A sterile alpha motif domain containing 4A
SCN1A sodium channel, voltage gated, type I alpha subunit
SERGEF secretion regulating guanine nucleotide exchange factor
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SIRT5 sirtuin 5
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SNCG synuclein, gamma (breast cancer-specific protein 1)
SRRT serrate, RNA effector molecule
STXBP6 syntaxin binding protein 6 (amisyn)
TBL1Y transducin (beta)-like 1, Y-linked
TLR8 toll-like receptor 8
TMEM212 transmembrane protein 212
TRIM29 tripartite motif containing 29
TRPM2 transient receptor potential cation channel, subfamily M, member 2
YOD1 YOD1 deubiquitinase
ZFP64 ZFP64 zinc finger protein
ZNF37BP zinc finger protein 37B, pseudogene

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
AFAP1 actin filament associated protein 1
AMPD1 adenosine monophosphate deaminase 1
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
AUTS2 autism susceptibility candidate 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAHCC1 BAH domain and coiled-coil containing 1
BCORL1 BCL6 corepressor-like 1
C14ORF93 chromosome 14 open reading frame 93
C1QTNF3 C1q and tumor necrosis factor related protein 3
CA11 carbonic anhydrase XI
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNO cyclin O
CDK18 cyclin-dependent kinase 18
CDK20 cyclin-dependent kinase 20
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEP70 centrosomal protein 70kDa
CHKB choline kinase beta
CIDEC cell death-inducing DFFA-like effector c
CLSTN1 calsyntenin 1
DEFA4 defensin, alpha 4, corticostatin
DENND4A DENN/MADD domain containing 4A
DMTN dematin actin binding protein
DNAL4 dynein, axonemal, light chain 4
DOK2 docking protein 2, 56kDa
ERN2 endoplasmic reticulum to nucleus signaling 2
EVPL envoplakin
F3 coagulation factor III (thromboplastin, tissue factor)
FBXO2 F-box protein 2
FLJ22184
FPGT fucose-1-phosphate guanylyltransferase
FRK fyn-related Src family tyrosine kinase
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLS2 glutaminase 2 (liver, mitochondrial)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HIST1H1E histone cluster 1, H1e
HS1BP3 HCLS1 binding protein 3
ITGA10 integrin, alpha 10
ITPKB inositol-trisphosphate 3-kinase B
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF13A kinesin family member 13A
LRRC61 leucine rich repeat containing 61
LY6D lymphocyte antigen 6 complex, locus D
MAL mal, T-cell differentiation protein
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MRPL2 mitochondrial ribosomal protein L2
MXD3 MAX dimerization protein 3
NAV2 neuron navigator 2
NCAM2 neural cell adhesion molecule 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPM3 nucleophosmin/nucleoplasmin 3
NRGN neurogranin (protein kinase C substrate, RC3)
NUP62CL nucleoporin 62kDa C-terminal like
NYNRIN NYN domain and retroviral integrase containing
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSMR oncostatin M receptor
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PALM paralemmin
PARG poly (ADP-ribose) glycohydrolase
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRF1 perforin 1 (pore forming protein)
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
R3HCC1L R3H domain and coiled-coil containing 1-like
RFTN1 raftlin, lipid raft linker 1
RNF39 ring finger protein 39
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RP2 retinitis pigmentosa 2 (X-linked recessive)
SCGB2A2 secretoglobin, family 2A, member 2
SH2D4A SH2 domain containing 4A
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLIT2 slit homolog 2 (Drosophila)
SNAI2 snail family zinc finger 2
SP1 Sp1 transcription factor
SPINK5 serine peptidase inhibitor, Kazal type 5
SPON2 spondin 2, extracellular matrix protein
TLR2 toll-like receptor 2
TM6SF1 transmembrane 6 superfamily member 1
TMC7 transmembrane channel-like 7
TMEM104 transmembrane protein 104
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIM21 tripartite motif containing 21
TRIM68 tripartite motif containing 68
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UBQLN4 ubiquilin 4
ULBP2 UL16 binding protein 2
WDR25 WD repeat domain 25
ZBTB6 zinc finger and BTB domain containing 6
ZFHX2 zinc finger homeobox 2
ZNF10 zinc finger protein 10
ZNF586 zinc finger protein 586
ZNF668 zinc finger protein 668
ZNF862 zinc finger protein 862