phenelzine-2357 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

195 genes differentially expressed following the phenelzine-2357 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AFF2 AF4/FMR2 family, member 2
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
APOE apolipoprotein E
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARMCX4 armadillo repeat containing, X-linked 4
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP9A ATPase, class II, type 9A
BIN1 bridging integrator 1
BIRC7 baculoviral IAP repeat containing 7
CAV2 caveolin 2
CBX8 chromobox homolog 8
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHPF chondroitin polymerizing factor
CLTA clathrin, light chain A
COL15A1 collagen, type XV, alpha 1
COL8A1 collagen, type VIII, alpha 1
CPED1 cadherin-like and PC-esterase domain containing 1
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRTC1 CREB regulated transcription coactivator 1
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DCN decorin
DMRT1 doublesex and mab-3 related transcription factor 1
DRP2 dystrophin related protein 2
EDN3 endothelin 3
EFNB3 ephrin-B3
ESR1 estrogen receptor 1
EXT1 exostosin glycosyltransferase 1
FAM184A family with sequence similarity 184, member A
FAM63A family with sequence similarity 63, member A
FBXO41 F-box protein 41
FGF23 fibroblast growth factor 23
FGF6 fibroblast growth factor 6
FRMPD1 FERM and PDZ domain containing 1
GFER growth factor, augmenter of liver regeneration
GIF gastric intrinsic factor (vitamin B synthesis)
GLS glutaminase
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HRH1 histamine receptor H1
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IGSF1 immunoglobulin superfamily, member 1
INSL5 insulin-like 5
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCTD13 potassium channel tetramerization domain containing 13
KIAA1045 KIAA1045
KIF25 kinesin family member 25
KRT8P12 keratin 8 pseudogene 12
LIN7B lin-7 homolog B (C. elegans)
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LPP LIM domain containing preferred translocation partner in lipoma
MCTP2 multiple C2 domains, transmembrane 2
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MRPS12 mitochondrial ribosomal protein S12
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEB nebulin
NFIB nuclear factor I/B
NRG2 neuregulin 2
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDE12 phosphodiesterase 12
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PTAFR platelet-activating factor receptor
PTGDS prostaglandin D2 synthase 21kDa (brain)
RGS4 regulator of G-protein signaling 4
RHAG Rh-associated glycoprotein
RIN3 Ras and Rab interactor 3
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNF19B ring finger protein 19B
RPLP2 ribosomal protein, large, P2
RUNX1 runt-related transcription factor 1
SEC14L1 SEC14-like 1 (S. cerevisiae)
SH2B1 SH2B adaptor protein 1
SHROOM2 shroom family member 2
SLC16A6 solute carrier family 16, member 6
SLC17A2 solute carrier family 17, member 2
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SPRR1A small proline-rich protein 1A
SPTBN1 spectrin, beta, non-erythrocytic 1
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SSTR4 somatostatin receptor 4
STOML1 stomatin (EPB72)-like 1
TBX10 T-box 10
TJAP1 tight junction associated protein 1 (peripheral)
TMEM104 transmembrane protein 104
TMPRSS15 transmembrane protease, serine 15
TPMT thiopurine S-methyltransferase
TRIM23 tripartite motif containing 23
TSC22D2 TSC22 domain family, member 2
UBA6 ubiquitin-like modifier activating enzyme 6
UHRF1BP1L UHRF1 binding protein 1-like
VCAN versican
ZBTB33 zinc finger and BTB domain containing 33
ZBTB43 zinc finger and BTB domain containing 43
ZC4H2 zinc finger, C4H2 domain containing

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACAD10 acyl-CoA dehydrogenase family, member 10
ACPP acid phosphatase, prostate
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADGRE2 adhesion G protein-coupled receptor E2
AEN apoptosis enhancing nuclease
AGO4 argonaute RISC catalytic component 4
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BCL2L2 BCL2-like 2
BPI bactericidal/permeability-increasing protein
C10ORF88 chromosome 10 open reading frame 88
C2CD2 C2 calcium-dependent domain containing 2
C3 complement component 3
CAPN5 calpain 5
CCDC15 coiled-coil domain containing 15
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK6 cyclin-dependent kinase 6
CHMP1A charged multivesicular body protein 1A
CIC capicua transcriptional repressor
CINP cyclin-dependent kinase 2 interacting protein
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCP1A decapping mRNA 1A
DDN dendrin
DOLPP1 dolichyldiphosphatase 1
FAM188A family with sequence similarity 188, member A
FBXO46 F-box protein 46
FHL3 four and a half LIM domains 3
FILIP1L filamin A interacting protein 1-like
FKBPL FK506 binding protein like
GIPC1 GIPC PDZ domain containing family, member 1
GMEB1 glucocorticoid modulatory element binding protein 1
GMPPA GDP-mannose pyrophosphorylase A
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GOLGA3 golgin A3
GPR22 G protein-coupled receptor 22
GPR65 G protein-coupled receptor 65
HIST1H2AJ histone cluster 1, H2aj
IFT46 intraflagellar transport 46
IFT81 intraflagellar transport 81
IMPAD1 inositol monophosphatase domain containing 1
ITGB7 integrin, beta 7
ITPKB inositol-trisphosphate 3-kinase B
JADE3 jade family PHD finger 3
KIF18A kinesin family member 18A
MTMR11 myotubularin related protein 11
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NPDC1 neural proliferation, differentiation and control, 1
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRGN neurogranin (protein kinase C substrate, RC3)
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PCYOX1 prenylcysteine oxidase 1
PDGFC platelet derived growth factor C
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PDZD8 PDZ domain containing 8
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
POLM polymerase (DNA directed), mu
PTCD2 pentatricopeptide repeat domain 2
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB3A RAB3A, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RFPL1S RFPL1 antisense RNA 1
RHOC ras homolog family member C
RINT1 RAD50 interactor 1
RNF126P1 ring finger protein 126 pseudogene 1
SESN1 sestrin 1
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SNX15 sorting nexin 15
SOAT1 sterol O-acyltransferase 1
SPIDR scaffolding protein involved in DNA repair
SREBF1 sterol regulatory element binding transcription factor 1
SSBP3 single stranded DNA binding protein 3
SSFA2 sperm specific antigen 2
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TBXAS1 thromboxane A synthase 1 (platelet)
TGM5 transglutaminase 5
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM110 transmembrane protein 110
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM254 transmembrane protein 254
TRAPPC13 trafficking protein particle complex 13
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSC22D1 TSC22 domain family, member 1
TTPAL tocopherol (alpha) transfer protein-like
TUBA3C tubulin, alpha 3c
WDR19 WD repeat domain 19
YPEL5 yippee-like 5 (Drosophila)
ZBED8 zinc finger, BED-type containing 8
ZNF580 zinc finger protein 580
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN9 zinc finger and SCAN domain containing 9