phenelzine-4360 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the phenelzine-4360 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ACPP acid phosphatase, prostate
ADORA3 adenosine A3 receptor
APC2 adenomatosis polyposis coli 2
ATF5 activating transcription factor 5
ATN1 atrophin 1
ATXN7L1 ataxin 7-like 1
AVPR1A arginine vasopressin receptor 1A
BTF3P11 basic transcription factor 3 pseudogene 11
BTN3A1 butyrophilin, subfamily 3, member A1
C10ORF12 chromosome 10 open reading frame 12
C19ORF66 chromosome 19 open reading frame 66
C2 complement component 2
C22ORF31 chromosome 22 open reading frame 31
CALB1 calbindin 1, 28kDa
CD47 CD47 molecule
COL13A1 collagen, type XIII, alpha 1
CPA4 carboxypeptidase A4
CREBBP CREB binding protein
CTIF CBP80/20-dependent translation initiation factor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DPF3 D4, zinc and double PHD fingers, family 3
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO21 F-box protein 21
FER1L4 fer-1-like family member 4, pseudogene (functional)
FMO5 flavin containing monooxygenase 5
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GIF gastric intrinsic factor (vitamin B synthesis)
GK glycerol kinase
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GRM4 glutamate receptor, metabotropic 4
GRPR gastrin-releasing peptide receptor
GTPBP10 GTP-binding protein 10 (putative)
H2AFX H2A histone family, member X
HOXB6 homeobox B6
HRG histidine-rich glycoprotein
HSF4 heat shock transcription factor 4
IGKV3-20 immunoglobulin kappa variable 3-20
IL36G interleukin 36, gamma
INHBA inhibin, beta A
IRF8 interferon regulatory factor 8
JRK Jrk homolog (mouse)
KLF6 Kruppel-like factor 6
KRT19P2 keratin 19 pseudogene 2
KRT23 keratin 23, type I
LIMK1 LIM domain kinase 1
LSP1 lymphocyte-specific protein 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MED25 mediator complex subunit 25
MORC1 MORC family CW-type zinc finger 1
MRPL41 mitochondrial ribosomal protein L41
MSI1 musashi RNA-binding protein 1
MUC3B mucin 3B, cell surface associated
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NKX2-5 NK2 homeobox 5
NT5M 5',3'-nucleotidase, mitochondrial
NXPE3 neurexophilin and PC-esterase domain family, member 3
NXPH3 neurexophilin 3
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PALM paralemmin
PARVA parvin, alpha
PNMAL1 paraneoplastic Ma antigen family-like 1
PNPLA3 patatin-like phospholipase domain containing 3
PPARA peroxisome proliferator-activated receptor alpha
PRSS2 protease, serine, 2 (trypsin 2)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAB6B RAB6B, member RAS oncogene family
RIMS1 regulating synaptic membrane exocytosis 1
RPL3L ribosomal protein L3-like
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
RRAD Ras-related associated with diabetes
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
RSG1 REM2 and RAB-like small GTPase 1
SH3BP2 SH3-domain binding protein 2
SIT1 signaling threshold regulating transmembrane adaptor 1
SLA Src-like-adaptor
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SULT4A1 sulfotransferase family 4A, member 1
T T, brachyury homolog (mouse)
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBXA2R thromboxane A2 receptor
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
THRB thyroid hormone receptor, beta
TIMP4 TIMP metallopeptidase inhibitor 4
TMEM144 transmembrane protein 144
TMEM246 transmembrane protein 246
TRIM36 tripartite motif containing 36
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VWA5A von Willebrand factor A domain containing 5A
WSCD1 WSC domain containing 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADM adrenomedullin
ARMC4 armadillo repeat containing 4
ARRB1 arrestin, beta 1
BAHCC1 BAH domain and coiled-coil containing 1
BCAS4 breast carcinoma amplified sequence 4
C16ORF58 chromosome 16 open reading frame 58
C5ORF45 chromosome 5 open reading frame 45
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMTA2 calmodulin binding transcription activator 2
CBX8 chromobox homolog 8
CCDC9 coiled-coil domain containing 9
CDK20 cyclin-dependent kinase 20
CHST10 carbohydrate sulfotransferase 10
CLDN9 claudin 9
CRLF1 cytokine receptor-like factor 1
CTSD cathepsin D
CUZD1 CUB and zona pellucida-like domains 1
DBF4B DBF4 zinc finger B
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DGAT1 diacylglycerol O-acyltransferase 1
FKRP fukutin related protein
GALK1 galactokinase 1
GTF2I general transcription factor IIi
HDAC7 histone deacetylase 7
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIST1H2AK histone cluster 1, H2ak
INPP1 inositol polyphosphate-1-phosphatase
IRF1 interferon regulatory factor 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JMJD4 jumonji domain containing 4
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KLHL26 kelch-like family member 26
LIN7B lin-7 homolog B (C. elegans)
LMBR1L limb development membrane protein 1-like
LOC390998 ribosomal protein L10 pseudogene
LRRC37A3 leucine rich repeat containing 37, member A3
LZTR1 leucine-zipper-like transcription regulator 1
MDK midkine (neurite growth-promoting factor 2)
METRN meteorin, glial cell differentiation regulator
MFAP2 microfibrillar-associated protein 2
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MXD3 MAX dimerization protein 3
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NT5C 5', 3'-nucleotidase, cytosolic
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
ONECUT2 one cut homeobox 2
PCSK7 proprotein convertase subtilisin/kexin type 7
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PODXL2 podocalyxin-like 2
POM121 POM121 transmembrane nucleoporin
POMT2 protein-O-mannosyltransferase 2
PORCN porcupine homolog (Drosophila)
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB17 RAB17, member RAS oncogene family
RAB30 RAB30, member RAS oncogene family
RNF126P1 ring finger protein 126 pseudogene 1
RPAP1 RNA polymerase II associated protein 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIX1 SIX homeobox 1
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SP1 Sp1 transcription factor
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TCTN1 tectonic family member 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THBS3 thrombospondin 3
TMEM121 transmembrane protein 121
TNS2 tensin 2
TOP3B topoisomerase (DNA) III beta
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM25 tripartite motif containing 25
TSPO translocator protein (18kDa)
TTLL1 tubulin tyrosine ligase-like family member 1
UNC119 unc-119 homolog (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
UPK3B uroplakin 3B
USP20 ubiquitin specific peptidase 20
VAX2 ventral anterior homeobox 2
VIPR1 vasoactive intestinal peptide receptor 1
WDR91 WD repeat domain 91
ZNF219 zinc finger protein 219
ZNF446 zinc finger protein 446
ZNF480 zinc finger protein 480
ZNF551 zinc finger protein 551
ZNF593 zinc finger protein 593
ZNF74 zinc finger protein 74