phenelzine-4538 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the phenelzine-4538 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ACOT11 acyl-CoA thioesterase 11
ADPRH ADP-ribosylarginine hydrolase
AKR1C2 aldo-keto reductase family 1, member C2
B9D2 B9 protein domain 2
BCAM basal cell adhesion molecule (Lutheran blood group)
CDC5L cell division cycle 5-like
CEND1 cell cycle exit and neuronal differentiation 1
CEP162 centrosomal protein 162kDa
CFAP45 cilia and flagella associated protein 45
CISH cytokine inducible SH2-containing protein
CPA4 carboxypeptidase A4
CPZ carboxypeptidase Z
CREBZF CREB/ATF bZIP transcription factor
CTSS cathepsin S
CXORF21 chromosome X open reading frame 21
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYTH1 cytohesin 1
DAPK3 death-associated protein kinase 3
DCLK2 doublecortin-like kinase 2
DCN decorin
DLC1 DLC1 Rho GTPase activating protein
DOCK6 dedicator of cytokinesis 6
DST dystonin
E2F4 E2F transcription factor 4, p107/p130-binding
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
FBXL7 F-box and leucine-rich repeat protein 7
FBXO31 F-box protein 31
FGF5 fibroblast growth factor 5
FH fumarate hydratase
FLJ11710 uncharacterized protein FLJ11710
FNDC3A fibronectin type III domain containing 3A
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXE3 forkhead box E3
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRS3 fibroblast growth factor receptor substrate 3
FUBP1 far upstream element (FUSE) binding protein 1
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GPR161 G protein-coupled receptor 161
GPR22 G protein-coupled receptor 22
HEMK1 HemK methyltransferase family member 1
HOMER3 homer scaffolding protein 3
HPCAL4 hippocalcin like 4
IFNA14 interferon, alpha 14
IQCK IQ motif containing K
IRAK4 interleukin-1 receptor-associated kinase 4
IRF4 interferon regulatory factor 4
KHK ketohexokinase (fructokinase)
KIAA0040 KIAA0040
LIG4 ligase IV, DNA, ATP-dependent
LRRC15 leucine rich repeat containing 15
LY9 lymphocyte antigen 9
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
METTL7A methyltransferase like 7A
MFAP3L microfibrillar-associated protein 3-like
MFN2 mitofusin 2
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRPL41 mitochondrial ribosomal protein L41
NF1 neurofibromin 1
NGF nerve growth factor (beta polypeptide)
NOVA2 neuro-oncological ventral antigen 2
NRL neural retina leucine zipper
NUP50 nucleoporin 50kDa
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PDE11A phosphodiesterase 11A
PRDX2 peroxiredoxin 2
PRKCA protein kinase C, alpha
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPRH protein tyrosine phosphatase, receptor type, H
RAB11B RAB11B, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RBMS3 RNA binding motif, single stranded interacting protein 3
RNF6 ring finger protein (C3H2C3 type) 6
SARM1 sterile alpha and TIR motif containing 1
SDS serine dehydratase
SGK2 serum/glucocorticoid regulated kinase 2
SOS2 son of sevenless homolog 2 (Drosophila)
SPTBN1 spectrin, beta, non-erythrocytic 1
STK17B serine/threonine kinase 17b
STS steroid sulfatase (microsomal), isozyme S
TCP10 t-complex 10
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TK2 thymidine kinase 2, mitochondrial
TMEM246 transmembrane protein 246
TMOD1 tropomodulin 1
TP53I11 tumor protein p53 inducible protein 11
TRD T cell receptor delta locus
TRIM3 tripartite motif containing 3
TTC12 tetratricopeptide repeat domain 12
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
WSB1 WD repeat and SOCS box containing 1
WT1 Wilms tumor 1
ZNF219 zinc finger protein 219
ZNF362 zinc finger protein 362
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
ANXA2P1 annexin A2 pseudogene 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARMCX2 armadillo repeat containing, X-linked 2
BAAT bile acid CoA:amino acid N-acyltransferase
BAHCC1 BAH domain and coiled-coil containing 1
BAHD1 bromo adjacent homology domain containing 1
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF70 chromosome 17 open reading frame 70
CBX7 chromobox homolog 7
CCDC68 coiled-coil domain containing 68
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD68 CD68 molecule
CD70 CD70 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDH7 cadherin 7, type 2
CHML choroideremia-like (Rab escort protein 2)
CNTNAP3B contactin associated protein-like 3B
CPED1 cadherin-like and PC-esterase domain containing 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CUL9 cullin 9
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DBF4B DBF4 zinc finger B
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DPY19L2P2 DPY19L2 pseudogene 2
EFNA3 ephrin-A3
FAM114A2 family with sequence similarity 114, member A2
FANCC Fanconi anemia, complementation group C
FANCE Fanconi anemia, complementation group E
FAT4 FAT atypical cadherin 4
FBRS fibrosin
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FOXN2 forkhead box N2
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GLS2 glutaminase 2 (liver, mitochondrial)
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC7 histone deacetylase 7
HDAC9 histone deacetylase 9
HIST1H1D histone cluster 1, H1d
HIST1H2AK histone cluster 1, H2ak
HOXB9 homeobox B9
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KDM7A lysine (K)-specific demethylase 7A
KIFC1 kinesin family member C1
KLF3 Kruppel-like factor 3 (basic)
LIMS2 LIM and senescent cell antigen-like domains 2
LMNB1 lamin B1
LOC390998 ribosomal protein L10 pseudogene
LOC729164 hCG1732469
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LZTR1 leucine-zipper-like transcription regulator 1
MTA2 metastasis associated 1 family, member 2
NAG18 NAG18 mRNA
NME3 NME/NM23 nucleoside diphosphate kinase 3
NT5M 5',3'-nucleotidase, mitochondrial
ODF2 outer dense fiber of sperm tails 2
OSMR oncostatin M receptor
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PACS1 phosphofurin acidic cluster sorting protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PARPBP PARP1 binding protein
PDE12 phosphodiesterase 12
PELI1 pellino E3 ubiquitin protein ligase 1
PGPEP1 pyroglutamyl-peptidase I
PHKG2 phosphorylase kinase, gamma 2 (testis)
PID1 phosphotyrosine interaction domain containing 1
PLAC8 placenta-specific 8
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLH polymerase (DNA directed), eta
PRICKLE3 prickle homolog 3 (Drosophila)
PRR4 proline rich 4 (lacrimal)
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGL2 ral guanine nucleotide dissociation stimulator-like 2
ROGDI rogdi homolog (Drosophila)
SDC3 syndecan 3
SLC12A9 solute carrier family 12, member 9
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SOX12 SRY (sex determining region Y)-box 12
SRD5A3 steroid 5 alpha-reductase 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK16 serine/threonine kinase 16
STON1 stonin 1
SUGCT succinyl-CoA:glutarate-CoA transferase
TIGD6 tigger transposable element derived 6
TMEM132A transmembrane protein 132A
TMEM53 transmembrane protein 53
TMEM8B transmembrane protein 8B
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
VASH1 vasohibin 1
WNT10B wingless-type MMTV integration site family, member 10B
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
YOD1 YOD1 deubiquitinase
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF205 zinc finger protein 205
ZNF446 zinc finger protein 446
ZNF747 zinc finger protein 747