pheneticillin-6105 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the pheneticillin-6105 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ACTL8 actin-like 8
ADAM12 ADAM metallopeptidase domain 12
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADGRA2 adhesion G protein-coupled receptor A2
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
APOE apolipoprotein E
ARC activity-regulated cytoskeleton-associated protein
ATXN2L ataxin 2-like
CCDC181 coiled-coil domain containing 181
CD300C CD300c molecule
CD6 CD6 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDH18 cadherin 18, type 2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDON cell adhesion associated, oncogene regulated
CDY1 chromodomain protein, Y-linked, 1
COL3A1 collagen, type III, alpha 1
COL6A1 collagen, type VI, alpha 1
CXCR4 chemokine (C-X-C motif) receptor 4
DES desmin
DHRS12 dehydrogenase/reductase (SDR family) member 12
DOCK5 dedicator of cytokinesis 5
DOCK9 dedicator of cytokinesis 9
DOPEY2 dopey family member 2
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FAM153A family with sequence similarity 153, member A
FBXO4 F-box protein 4
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GP5 glycoprotein V (platelet)
GPR137 G protein-coupled receptor 137
GRK4 G protein-coupled receptor kinase 4
GSTA3 glutathione S-transferase alpha 3
GSTM5 glutathione S-transferase mu 5
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HGFAC HGF activator
IFI44 interferon-induced protein 44
IGFBP3 insulin-like growth factor binding protein 3
IGLJ3 immunoglobulin lambda joining 3
IGSF6 immunoglobulin superfamily, member 6
IQCA1 IQ motif containing with AAA domain 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KLF12 Kruppel-like factor 12
KLHDC8A kelch domain containing 8A
KRTAP1-3 keratin associated protein 1-3
LAMP1 lysosomal-associated membrane protein 1
LATS1 large tumor suppressor kinase 1
LPAR1 lysophosphatidic acid receptor 1
LRRC23 leucine rich repeat containing 23
MAB21L1 mab-21-like 1 (C. elegans)
MASP2 mannan-binding lectin serine peptidase 2
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NUP54 nucleoporin 54kDa
OMD osteomodulin
OR10H3 olfactory receptor, family 10, subfamily H, member 3
OR52A1 olfactory receptor, family 52, subfamily A, member 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PAPPA2 pappalysin 2
PDE10A phosphodiesterase 10A
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLEKHS1 pleckstrin homology domain containing, family S member 1
POLM polymerase (DNA directed), mu
POM121L2 POM121 transmembrane nucleoporin-like 2
POU4F2 POU class 4 homeobox 2
PPP5C protein phosphatase 5, catalytic subunit
PRB1 proline-rich protein BstNI subfamily 1
PSG4 pregnancy specific beta-1-glycoprotein 4
RNF122 ring finger protein 122
RNF32 ring finger protein 32
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RXRB retinoid X receptor, beta
SATB2 SATB homeobox 2
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SIPA1 signal-induced proliferation-associated 1
SOCS3 suppressor of cytokine signaling 3
SOD2 superoxide dismutase 2, mitochondrial
SRCAP Snf2-related CREBBP activator protein
STS steroid sulfatase (microsomal), isozyme S
TCP11L1 t-complex 11, testis-specific-like 1
TGM2 transglutaminase 2
THSD7A thrombospondin, type I, domain containing 7A
TMPRSS15 transmembrane protease, serine 15
TOP3B topoisomerase (DNA) III beta
TRBC1 T cell receptor beta constant 1
TRH thyrotropin-releasing hormone
TRIL TLR4 interactor with leucine-rich repeats
TRIM10 tripartite motif containing 10
VPRBP Vpr (HIV-1) binding protein
XCR1 chemokine (C motif) receptor 1
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
AFF4 AF4/FMR2 family, member 4
AMPH amphiphysin
BAHCC1 BAH domain and coiled-coil containing 1
C2ORF44 chromosome 2 open reading frame 44
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCDC186 coiled-coil domain containing 186
CD79A CD79a molecule, immunoglobulin-associated alpha
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CFAP45 cilia and flagella associated protein 45
CHKB choline kinase beta
CSF1R colony stimulating factor 1 receptor
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DNAH17 dynein, axonemal, heavy chain 17
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DYSF dysferlin
ELSPBP1 epididymal sperm binding protein 1
FAAH fatty acid amide hydrolase
FAM155A family with sequence similarity 155, member A
FAM160B2 family with sequence similarity 160, member B2
FAM198B family with sequence similarity 198, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FRMPD1 FERM and PDZ domain containing 1
GPR85 G protein-coupled receptor 85
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRAMD1C GRAM domain containing 1C
HDAC11 histone deacetylase 11
HIST1H2BC histone cluster 1, H2bc
HIST1H4D histone cluster 1, H4d
HOXC8 homeobox C8
HSPA1L heat shock 70kDa protein 1-like
IFI35 interferon-induced protein 35
ING4 inhibitor of growth family, member 4
IQSEC2 IQ motif and Sec7 domain 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KIAA0319L KIAA0319-like
KIAA0754 KIAA0754
KIF13A kinesin family member 13A
KREMEN2 kringle containing transmembrane protein 2
LIMS2 LIM and senescent cell antigen-like domains 2
LINC01587 long intergenic non-protein coding RNA 1587
LOC100286895 cell division cycle 27 homolog pseudogene
LOC390998 ribosomal protein L10 pseudogene
LOC729164 hCG1732469
LOXL3 lysyl oxidase-like 3
LPXN leupaxin
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MVP major vault protein
MYLK myosin light chain kinase
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PDE8B phosphodiesterase 8B
PDGFD platelet derived growth factor D
PHOX2A paired-like homeobox 2a
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
RAB3D RAB3D, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFPL1S RFPL1 antisense RNA 1
ROM1 retinal outer segment membrane protein 1
RPL10L ribosomal protein L10-like
S100A2 S100 calcium binding protein A2
SCHIP1 schwannomin interacting protein 1
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SENP7 SUMO1/sentrin specific peptidase 7
SGCE sarcoglycan, epsilon
SLC12A9 solute carrier family 12, member 9
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SPAG7 sperm associated antigen 7
SPRR1B small proline-rich protein 1B
TARP TCR gamma alternate reading frame protein
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRAIP TRAF interacting protein
TSPAN1 tetraspanin 1
TSPAN15 tetraspanin 15
TTC30A tetratricopeptide repeat domain 30A
VASH2 vasohibin 2
VEGFB vascular endothelial growth factor B
VEZT vezatin, adherens junctions transmembrane protein
VIM vimentin
VPS9D1 VPS9 domain containing 1
WLS wntless Wnt ligand secretion mediator
WNT10B wingless-type MMTV integration site family, member 10B
XYLT2 xylosyltransferase II
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZIC3 Zic family member 3
ZNF428 zinc finger protein 428
ZNF446 zinc finger protein 446
ZSCAN2 zinc finger and SCAN domain containing 2