phenindione-1718 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the phenindione-1718 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ACAN aggrecan
ADD3 adducin 3 (gamma)
ANKMY1 ankyrin repeat and MYND domain containing 1
ANXA2P2 annexin A2 pseudogene 2
APP amyloid beta (A4) precursor protein
AQP8 aquaporin 8
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARRB2 arrestin, beta 2
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP5SL ATP5S-like
BCAT1 branched chain amino-acid transaminase 1, cytosolic
C14ORF93 chromosome 14 open reading frame 93
C21ORF91 chromosome 21 open reading frame 91
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CAMK1G calcium/calmodulin-dependent protein kinase IG
CASP8 caspase 8, apoptosis-related cysteine peptidase
CDC37L1 cell division cycle 37-like 1
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHPF2 chondroitin polymerizing factor 2
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNTN1 contactin 1
COPS2 COP9 signalosome subunit 2
DCAF15 DDB1 and CUL4 associated factor 15
DEAF1 DEAF1 transcription factor
DPH2 DPH2 homolog (S. cerevisiae)
DUS2 dihydrouridine synthase 2
ELK1 ELK1, member of ETS oncogene family
EVI5 ecotropic viral integration site 5
FANCF Fanconi anemia, complementation group F
FASTK Fas-activated serine/threonine kinase
FBXL6 F-box and leucine-rich repeat protein 6
FBXO42 F-box protein 42
FZD7 frizzled class receptor 7
GLB1L2 galactosidase, beta 1-like 2
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GON4L gon-4-like (C. elegans)
GUCA1B guanylate cyclase activator 1B (retina)
HDAC5 histone deacetylase 5
HMGA2 high mobility group AT-hook 2
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HPS1 Hermansky-Pudlak syndrome 1
HYAL2 hyaluronoglucosaminidase 2
ITGB7 integrin, beta 7
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLF6 Kruppel-like factor 6
KLHL18 kelch-like family member 18
LPAR1 lysophosphatidic acid receptor 1
LRP12 low density lipoprotein receptor-related protein 12
MAP3K7CL MAP3K7 C-terminal like
MBOAT7 membrane bound O-acyltransferase domain containing 7
MCC mutated in colorectal cancers
MED20 mediator complex subunit 20
METTL13 methyltransferase like 13
MRPL12 mitochondrial ribosomal protein L12
MST1 macrophage stimulating 1
NOV nephroblastoma overexpressed
NPIPB3 nuclear pore complex interacting protein family, member B3
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PKP3 plakophilin 3
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLEK2 pleckstrin 2
RCE1 Ras converting CAAX endopeptidase 1
RHOT2 ras homolog family member T2
RNASE3 ribonuclease, RNase A family, 3
RNF24 ring finger protein 24
RPS2 ribosomal protein S2
SALL2 spalt-like transcription factor 2
SF3B3 splicing factor 3b, subunit 3, 130kDa
SIDT2 SID1 transmembrane family, member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNX19 sorting nexin 19
SOX4 SRY (sex determining region Y)-box 4
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SYNGR1 synaptogyrin 1
TBL1X transducin (beta)-like 1X-linked
TCTN1 tectonic family member 1
TDRD3 tudor domain containing 3
TMED9 transmembrane emp24 protein transport domain containing 9
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRRAP transformation/transcription domain-associated protein
TTC3 tetratricopeptide repeat domain 3
TUSC2 tumor suppressor candidate 2
UBE2O ubiquitin-conjugating enzyme E2O
VENTX VENT homeobox
WDR13 WD repeat domain 13
WIZ widely interspaced zinc finger motifs
WT1 Wilms tumor 1
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZMYM1 zinc finger, MYM-type 1
ZNF24 zinc finger protein 24
ZNF248 zinc finger protein 248

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ADORA3 adenosine A3 receptor
APOBR apolipoprotein B receptor
ARHGAP10 Rho GTPase activating protein 10
ASAP1-IT1 ASAP1 intronic transcript 1
ASTE1 asteroid homolog 1 (Drosophila)
ATXN2 ataxin 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL7C B-cell CLL/lymphoma 7C
BRD9 bromodomain containing 9
BTK Bruton agammaglobulinemia tyrosine kinase
C1ORF216 chromosome 1 open reading frame 216
C1ORF35 chromosome 1 open reading frame 35
C1QTNF1 C1q and tumor necrosis factor related protein 1
CCDC47 coiled-coil domain containing 47
CCDC91 coiled-coil domain containing 91
CD151 CD151 molecule (Raph blood group)
CNPY3 canopy FGF signaling regulator 3
CRTAP cartilage associated protein
CSAD cysteine sulfinic acid decarboxylase
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTSK cathepsin K
DDHD2 DDHD domain containing 2
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DSN1 DSN1, MIS12 kinetochore complex component
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
ECM1 extracellular matrix protein 1
EFCAB2 EF-hand calcium binding domain 2
EXOSC9 exosome component 9
FADS2 fatty acid desaturase 2
FGL1 fibrinogen-like 1
FKTN fukutin
FOCAD focadhesin
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR27 G protein-coupled receptor 27
GPRC5D G protein-coupled receptor, class C, group 5, member D
GRM6 glutamate receptor, metabotropic 6
HACD3 3-hydroxyacyl-CoA dehydratase 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIRA histone cell cycle regulator
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
LRRC42 leucine rich repeat containing 42
LRRK1 leucine-rich repeat kinase 1
MAGEF1 melanoma antigen family F1
MBTD1 mbt domain containing 1
MEST mesoderm specific transcript
MGC12488
MRPL49 mitochondrial ribosomal protein L49
MRPS15 mitochondrial ribosomal protein S15
MTG1 mitochondrial ribosome-associated GTPase 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MYNN myoneurin
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
NECAB3 N-terminal EF-hand calcium binding protein 3
NINJ1 ninjurin 1
NUBP2 nucleotide binding protein 2
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
NXF3 nuclear RNA export factor 3
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
ORC2 origin recognition complex, subunit 2
PARP12 poly (ADP-ribose) polymerase family, member 12
PELI1 pellino E3 ubiquitin protein ligase 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PNOC prepronociceptin
PODNL1 podocan-like 1
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRR14L proline rich 14-like
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RCL1 RNA terminal phosphate cyclase-like 1
RHOH ras homolog family member H
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH3GL1 SH3-domain GRB2-like 1
SLC22A14 solute carrier family 22, member 14
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SNHG3 small nucleolar RNA host gene 3
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMEM14A transmembrane protein 14A
TMEM156 transmembrane protein 156
TMEM242 transmembrane protein 242
TMEM246 transmembrane protein 246
TMPRSS6 transmembrane protease, serine 6
TOE1 target of EGR1, member 1 (nuclear)
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRIM9 tripartite motif containing 9
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC31 tetratricopeptide repeat domain 31
TUBA4B tubulin, alpha 4b
TUBG1 tubulin, gamma 1
WRN Werner syndrome, RecQ helicase-like
ZNF189 zinc finger protein 189