phenindione-5991 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the phenindione-5991 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADRA1A adrenoceptor alpha 1A
AHSP alpha hemoglobin stabilizing protein
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANGPT4 angiopoietin 4
APOM apolipoprotein M
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BTN2A2 butyrophilin, subfamily 2, member A2
C9ORF156 chromosome 9 open reading frame 156
CABIN1 calcineurin binding protein 1
CALD1 caldesmon 1
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DENND5B DENN/MADD domain containing 5B
DMTN dematin actin binding protein
DTNA dystrobrevin, alpha
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ECM1 extracellular matrix protein 1
EGFR epidermal growth factor receptor
EMID1 EMI domain containing 1
FADS3 fatty acid desaturase 3
FAM134B family with sequence similarity 134, member B
FBLN1 fibulin 1
FHL1 four and a half LIM domains 1
FLOT1 flotillin 1
GFER growth factor, augmenter of liver regeneration
GGT1 gamma-glutamyltransferase 1
GP5 glycoprotein V (platelet)
GPATCH4 G patch domain containing 4
GPR137 G protein-coupled receptor 137
GPR37L1 G protein-coupled receptor 37 like 1
GRIK1 glutamate receptor, ionotropic, kainate 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HSPB11 heat shock protein family B (small), member 11
IFNA14 interferon, alpha 14
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KDM4C lysine (K)-specific demethylase 4C
KITLG KIT ligand
KRT6B keratin 6B, type II
KRTAP2-4 keratin associated protein 2-4
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LSP1 lymphocyte-specific protein 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAL mal, T-cell differentiation protein
METTL16 methyltransferase like 16
MLANA melan-A
MMP25 matrix metallopeptidase 25
MTSS1 metastasis suppressor 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOX1 NADPH oxidase 1
NR0B1 nuclear receptor subfamily 0, group B, member 1
OLFML2A olfactomedin-like 2A
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAUR plasminogen activator, urokinase receptor
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLD1 phospholipase D1, phosphatidylcholine-specific
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PML promyelocytic leukemia
POFUT1 protein O-fucosyltransferase 1
PPP4R4 protein phosphatase 4, regulatory subunit 4
PQLC2 PQ loop repeat containing 2
RAD54L2 RAD54-like 2 (S. cerevisiae)
RB1 retinoblastoma 1
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SH3BP2 SH3-domain binding protein 2
SIRT4 sirtuin 4
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNX13 sorting nexin 13
SSX1 synovial sarcoma, X breakpoint 1
STAG3 stromal antigen 3
STK11 serine/threonine kinase 11
SYBU syntabulin (syntaxin-interacting)
SYT13 synaptotagmin XIII
TCP11L1 t-complex 11, testis-specific-like 1
TENM1 teneurin transmembrane protein 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLX3 T-cell leukemia homeobox 3
TMCC2 transmembrane and coiled-coil domain family 2
TP53I11 tumor protein p53 inducible protein 11
TRIM21 tripartite motif containing 21
TTC39A tetratricopeptide repeat domain 39A
UBE2I ubiquitin-conjugating enzyme E2I
UBOX5 U-box domain containing 5
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WIZ widely interspaced zinc finger motifs
ZCCHC24 zinc finger, CCHC domain containing 24
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACSF2 acyl-CoA synthetase family member 2
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADGRG2 adhesion G protein-coupled receptor G2
AMH anti-Mullerian hormone
ANKRD36 ankyrin repeat domain 36
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
C11ORF80 chromosome 11 open reading frame 80
C4ORF29 chromosome 4 open reading frame 29
CBX4 chromobox homolog 4
CCDC88C coiled-coil domain containing 88C
CCNL2 cyclin L2
CD82 CD82 molecule
CIC capicua transcriptional repressor
CIDEB cell death-inducing DFFA-like effector b
CLSPN claspin
CRELD1 cysteine-rich with EGF-like domains 1
CXORF56 chromosome X open reading frame 56
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFNA4 ephrin-A4
FBRS fibrosin
FBXL6 F-box and leucine-rich repeat protein 6
FLT4 fms-related tyrosine kinase 4
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GLB1L2 galactosidase, beta 1-like 2
GPATCH3 G patch domain containing 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AI histone cluster 1, H2ai
HOXD11 homeobox D11
HYI hydroxypyruvate isomerase (putative)
IFITM1 interferon induced transmembrane protein 1
IFT22 intraflagellar transport 22
IFT81 intraflagellar transport 81
IL17RA interleukin 17 receptor A
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INO80D INO80 complex subunit D
IQSEC2 IQ motif and Sec7 domain 2
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIAA0319L KIAA0319-like
LIN7A lin-7 homolog A (C. elegans)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRC20 leucine rich repeat containing 20
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MATK megakaryocyte-associated tyrosine kinase
MTG1 mitochondrial ribosome-associated GTPase 1
NAG18 NAG18 mRNA
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PDE12 phosphodiesterase 12
PDE8B phosphodiesterase 8B
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PODXL2 podocalyxin-like 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RNF2 ring finger protein 2
RPS17P5 ribosomal protein S17 pseudogene 5
RSF1 remodeling and spacing factor 1
SAV1 salvador family WW domain containing protein 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD8 SET domain containing (lysine methyltransferase) 8
SH2B3 SH2B adaptor protein 3
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SPINK4 serine peptidase inhibitor, Kazal type 4
SPINK5 serine peptidase inhibitor, Kazal type 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM121 transmembrane protein 121
TMEM183A transmembrane protein 183A
TMEM212 transmembrane protein 212
TTC23 tetratricopeptide repeat domain 23
UBXN6 UBX domain protein 6
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WFDC2 WAP four-disulfide core domain 2
XAB2 XPA binding protein 2
XK X-linked Kx blood group
ZBTB6 zinc finger and BTB domain containing 6
ZFP37 ZFP37 zinc finger protein
ZNF250 zinc finger protein 250
ZNF324 zinc finger protein 324
ZNF329 zinc finger protein 329
ZNF408 zinc finger protein 408
ZNF623 zinc finger protein 623
ZNF652 zinc finger protein 652
ZNF668 zinc finger protein 668
ZNF669 zinc finger protein 669
ZNRD1-AS1 ZNRD1 antisense RNA 1