pheniramine-4012 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the pheniramine-4012 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
AIM2 absent in melanoma 2
ARTN artemin
ATP10B ATPase, class V, type 10B
ATRNL1 attractin-like 1
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
BEST1 bestrophin 1
BTN3A2 butyrophilin, subfamily 3, member A2
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CADM4 cell adhesion molecule 4
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCDC186 coiled-coil domain containing 186
CCL23 chemokine (C-C motif) ligand 23
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLSTN3 calsyntenin 3
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DLX5 distal-less homeobox 5
DPP4 dipeptidyl-peptidase 4
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EDDM3A epididymal protein 3A
EDN3 endothelin 3
FAM198B family with sequence similarity 198, member B
FBXO40 F-box protein 40
FLJ22184
FRMD8 FERM domain containing 8
GAB1 GRB2-associated binding protein 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPR135 G protein-coupled receptor 135
HEG1 heart development protein with EGF-like domains 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IL15 interleukin 15
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPK1 inositol-tetrakisphosphate 1-kinase
KAZN kazrin, periplakin interacting protein
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDSR 3-ketodihydrosphingosine reductase
KIAA0391 KIAA0391
KIF25-AS1 KIF25 antisense RNA 1
LBX1 ladybird homeobox 1
LIMD2 LIM domain containing 2
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRN3 leucine rich repeat neuronal 3
LUM lumican
MME membrane metallo-endopeptidase
MRAS muscle RAS oncogene homolog
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MTMR7 myotubularin related protein 7
MYB v-myb avian myeloblastosis viral oncogene homolog
NDRG2 NDRG family member 2
NPAS1 neuronal PAS domain protein 1
NPFFR1 neuropeptide FF receptor 1
NRG1 neuregulin 1
NRXN3 neurexin 3
OR10H1 olfactory receptor, family 10, subfamily H, member 1
PALM paralemmin
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PLA2G3 phospholipase A2, group III
PLA2G5 phospholipase A2, group V
PLAC4 placenta-specific 4
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRAF2 PRA1 domain family, member 2
PRKCE protein kinase C, epsilon
PRKCI protein kinase C, iota
PRTN3 proteinase 3
PTPRR protein tyrosine phosphatase, receptor type, R
PVR poliovirus receptor
RAB11B RAB11B, member RAS oncogene family
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RFXAP regulatory factor X-associated protein
RGS12 regulator of G-protein signaling 12
RGS16 regulator of G-protein signaling 16
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCN2B sodium channel, voltage gated, type II beta subunit
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SGSM3 small G protein signaling modulator 3
SLC25A30 solute carrier family 25, member 30
SLMO1 slowmo homolog 1 (Drosophila)
SOX5 SRY (sex determining region Y)-box 5
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
STK24 serine/threonine kinase 24
TACR1 tachykinin receptor 1
TAL1 T-cell acute lymphocytic leukemia 1
TBRG4 transforming growth factor beta regulator 4
TBX6 T-box 6
TMEM176A transmembrane protein 176A
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRGV5 T cell receptor gamma variable 5
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
ZNF362 zinc finger protein 362

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACIN1 apoptotic chromatin condensation inducer 1
AGO4 argonaute RISC catalytic component 4
ALS2CL ALS2 C-terminal like
ARC activity-regulated cytoskeleton-associated protein
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATP7B ATPase, Cu++ transporting, beta polypeptide
BAHCC1 BAH domain and coiled-coil containing 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BST1 bone marrow stromal cell antigen 1
C19ORF40 chromosome 19 open reading frame 40
C5ORF45 chromosome 5 open reading frame 45
CA9 carbonic anhydrase IX
CCNJL cyclin J-like
CIDEB cell death-inducing DFFA-like effector b
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRELD1 cysteine-rich with EGF-like domains 1
CUZD1 CUB and zona pellucida-like domains 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DNAH17 dynein, axonemal, heavy chain 17
EHF ets homologous factor
EPN1 epsin 1
ETNK2 ethanolamine kinase 2
EXO5 exonuclease 5
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM204A family with sequence similarity 204, member A
FBXL15 F-box and leucine-rich repeat protein 15
FBXL7 F-box and leucine-rich repeat protein 7
FER fer (fps/fes related) tyrosine kinase
GDAP1 ganglioside induced differentiation associated protein 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJA9 gap junction protein, alpha 9, 59kDa
HIST1H1T histone cluster 1, H1t
HIST1H3A histone cluster 1, H3a
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSF2BP heat shock transcription factor 2 binding protein
HSPA1L heat shock 70kDa protein 1-like
IFI35 interferon-induced protein 35
IFNA17 interferon, alpha 17
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL11RA interleukin 11 receptor, alpha
IL17RB interleukin 17 receptor B
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KDM4D lysine (K)-specific demethylase 4D
KDM5C lysine (K)-specific demethylase 5C
KDM7A lysine (K)-specific demethylase 7A
KRT8P12 keratin 8 pseudogene 12
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
MANBA mannosidase, beta A, lysosomal
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MMP3 matrix metallopeptidase 3
MNMIP1 manchette microtubule inner protein 1
MUM1 melanoma associated antigen (mutated) 1
MXD3 MAX dimerization protein 3
MYLIP myosin regulatory light chain interacting protein
NKX3-2 NK3 homeobox 2
NOL12 nucleolar protein 12
ONECUT2 one cut homeobox 2
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PADI1 peptidyl arginine deiminase, type I
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALMD palmdelphin
PHC1 polyhomeotic homolog 1 (Drosophila)
PIP prolactin-induced protein
PLA2G15 phospholipase A2, group XV
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
POMT2 protein-O-mannosyltransferase 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRKCD protein kinase C, delta
PRSS8 protease, serine, 8
PTPN3 protein tyrosine phosphatase, non-receptor type 3
R3HCC1L R3H domain and coiled-coil containing 1-like
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RUSC2 RUN and SH3 domain containing 2
RWDD2A RWD domain containing 2A
SARS2 seryl-tRNA synthetase 2, mitochondrial
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SHROOM2 shroom family member 2
SLAMF7 SLAM family member 7
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SND1-IT1 SND1 intronic transcript 1
SPATA1 spermatogenesis associated 1
SSTR4 somatostatin receptor 4
STK16 serine/threonine kinase 16
TAOK1 TAO kinase 1
TBC1D17 TBC1 domain family, member 17
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WDR76 WD repeat domain 76
XYLT2 xylosyltransferase II
ZFP30 ZFP30 zinc finger protein
ZNF268 zinc finger protein 268
ZNF528 zinc finger protein 528
ZNRD1-AS1 ZNRD1 antisense RNA 1