| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the phenoxybenzamine-5248 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ADCY7 | adenylate cyclase 7 |
| ADM | adrenomedullin |
| AKAP17A | A kinase (PRKA) anchor protein 17A |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATF3 | activating transcription factor 3 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| COL2A1 | collagen, type II, alpha 1 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTGF | connective tissue growth factor |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| EGR1 | early growth response 1 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| EPHA2 | EPH receptor A2 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FAS | Fas cell surface death receptor |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSL1 | FOS-like antigen 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HBEGF | heparin-binding EGF-like growth factor |
| HBP1 | HMG-box transcription factor 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IER5 | immediate early response 5 |
| IRS2 | insulin receptor substrate 2 |
| JMJD6 | jumonji domain containing 6 |
| JUN | jun proto-oncogene |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LIF | leukemia inhibitory factor |
| LOC157562 | uncharacterized LOC157562 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MIR22HG | MIR22 host gene |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1H | metallothionein 1H |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NGDN | neuroguidin, EIF4E binding protein |
| NHLH2 | nescient helix loop helix 2 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NUP88 | nucleoporin 88kDa |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PGF | placental growth factor |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POPDC3 | popeye domain containing 3 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RFPL2 | ret finger protein-like 2 |
| RGS2 | regulator of G-protein signaling 2 |
| RGS20 | regulator of G-protein signaling 20 |
| RIOK3 | RIO kinase 3 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SIK1 | salt-inducible kinase 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMIM7 | small integral membrane protein 7 |
| SNAI2 | snail family zinc finger 2 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| TES | testin LIM domain protein |
| TLR1 | toll-like receptor 1 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TSPYL2 | TSPY-like 2 |
| ZNF10 | zinc finger protein 10 |
| ZNF222 | zinc finger protein 222 |
| ZNF473 | zinc finger protein 473 |
| ZRSR1 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ANKRD36 | ankyrin repeat domain 36 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARRB1 | arrestin, beta 1 |
| B3GNT1 | |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CCNO | cyclin O |
| CENPF | centromere protein F, 350/400kDa |
| CEP97 | centrosomal protein 97kDa |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| DACH1 | dachshund family transcription factor 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DOCK1 | dedicator of cytokinesis 1 |
| DOCK4 | dedicator of cytokinesis 4 |
| E2F8 | E2F transcription factor 8 |
| EFNA4 | ephrin-A4 |
| EML4 | echinoderm microtubule associated protein like 4 |
| ERCC6L | excision repair cross-complementation group 6-like |
| FBXO5 | F-box protein 5 |
| FER | fer (fps/fes related) tyrosine kinase |
| FRK | fyn-related Src family tyrosine kinase |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GAN | gigaxonin |
| GATA4 | GATA binding protein 4 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GHR | growth hormone receptor |
| GLI3 | GLI family zinc finger 3 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF2I | general transcription factor IIi |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| H1F0 | H1 histone family, member 0 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4F | histone cluster 1, H4f |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HMGB3 | high mobility group box 3 |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGSF3 | immunoglobulin superfamily, member 3 |
| JAK2 | Janus kinase 2 |
| JARID2 | jumonji, AT rich interactive domain 2 |
| KIF18A | kinesin family member 18A |
| KIF20B | kinesin family member 20B |
| KLHL28 | kelch-like family member 28 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMNB1 | lamin B1 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MEGF9 | multiple EGF-like-domains 9 |
| MEIS1 | Meis homeobox 1 |
| MGC12488 | |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PRR15L | proline rich 15-like |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| PVRL3 | poliovirus receptor-related 3 |
| RAB30 | RAB30, member RAS oncogene family |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS19 | regulator of G-protein signaling 19 |
| RNF170 | ring finger protein 170 |
| RPL10L | ribosomal protein L10-like |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RSRC1 | arginine/serine-rich coiled-coil 1 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSBP2 | single-stranded DNA binding protein 2 |
| SUOX | sulfite oxidase |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TTC28 | tetratricopeptide repeat domain 28 |
| TXNIP | thioredoxin interacting protein |
| VAV3 | vav 3 guanine nucleotide exchange factor |
