| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the phenoxybenzamine-5613 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATF3 | activating transcription factor 3 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BDKRB2 | bradykinin receptor B2 |
| BTG2 | BTG family, member 2 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| COL2A1 | collagen, type II, alpha 1 |
| CREM | cAMP responsive element modulator |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DCTN1 | dynactin 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR1 | early growth response 1 |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| EPHA2 | EPH receptor A2 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FAS | Fas cell surface death receptor |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
| FLJ42627 | uncharacterized LOC645644 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSL1 | FOS-like antigen 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GUCA1B | guanylate cyclase activator 1B (retina) |
| HBEGF | heparin-binding EGF-like growth factor |
| HBP1 | HMG-box transcription factor 1 |
| HLA-E | major histocompatibility complex, class I, E |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IER5 | immediate early response 5 |
| IFT27 | intraflagellar transport 27 |
| INHBE | inhibin, beta E |
| IRS2 | insulin receptor substrate 2 |
| JMJD6 | jumonji domain containing 6 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 |
| KIAA0125 | KIAA0125 |
| KLHL25 | kelch-like family member 25 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LOC157562 | uncharacterized LOC157562 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NEK9 | NIMA-related kinase 9 |
| NHLH2 | nescient helix loop helix 2 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUP88 | nucleoporin 88kDa |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PGF | placental growth factor |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLLP | plasmolipin |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POPDC3 | popeye domain containing 3 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| RFPL2 | ret finger protein-like 2 |
| RGS2 | regulator of G-protein signaling 2 |
| RGS20 | regulator of G-protein signaling 20 |
| RND1 | Rho family GTPase 1 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SESN1 | sestrin 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMIM7 | small integral membrane protein 7 |
| SNAI2 | snail family zinc finger 2 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SQSTM1 | sequestosome 1 |
| TES | testin LIM domain protein |
| TMEM97 | transmembrane protein 97 |
| TSPYL2 | TSPY-like 2 |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZNF473 | zinc finger protein 473 |
| ZNF682 | zinc finger protein 682 |
| ZRSR1 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B3GNT1 | |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CBX8 | chromobox homolog 8 |
| CCDC85C | coiled-coil domain containing 85C |
| CD82 | CD82 molecule |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| E2F8 | E2F transcription factor 8 |
| EGR3 | early growth response 3 |
| ERCC6L | excision repair cross-complementation group 6-like |
| ESRP2 | epithelial splicing regulatory protein 2 |
| FAM155A | family with sequence similarity 155, member A |
| FBXO22 | F-box protein 22 |
| FBXO5 | F-box protein 5 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FER | fer (fps/fes related) tyrosine kinase |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GHR | growth hormone receptor |
| GLI3 | GLI family zinc finger 3 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GPHN | gephyrin |
| H1F0 | H1 histone family, member 0 |
| HIST1H1D | histone cluster 1, H1d |
| HMGB3 | high mobility group box 3 |
| IGSF3 | immunoglobulin superfamily, member 3 |
| IRX5 | iroquois homeobox 5 |
| JAK2 | Janus kinase 2 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LMNB1 | lamin B1 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 |
| MBD5 | methyl-CpG binding domain protein 5 |
| MEIS1 | Meis homeobox 1 |
| MKL2 | MKL/myocardin-like 2 |
| MPPED2 | metallophosphoesterase domain containing 2 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) |
| MXD3 | MAX dimerization protein 3 |
| NBEA | neurobeachin |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NPY1R | neuropeptide Y receptor Y1 |
| OLFML2A | olfactomedin-like 2A |
| OSMR | oncostatin M receptor |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PDE8B | phosphodiesterase 8B |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRR15L | proline rich 15-like |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| PTPRA | protein tyrosine phosphatase, receptor type, A |
| PVRL3 | poliovirus receptor-related 3 |
| RBM12 | RNA binding motif protein 12 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RHOB | ras homolog family member B |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIN2 | Ras and Rab interactor 2 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC25A12 | solute carrier family 25 (aspartate/glutamate carrier), member 12 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMAD7 | SMAD family member 7 |
| SSBP2 | single-stranded DNA binding protein 2 |
| SYTL2 | synaptotagmin-like 2 |
| TET3 | tet methylcytosine dioxygenase 3 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM223 | transmembrane protein 223 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TRIB2 | tribbles pseudokinase 2 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRPS1 | trichorhinophalangeal syndrome I |
| TTC28 | tetratricopeptide repeat domain 28 |
| UNC119 | unc-119 homolog (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| VANGL1 | VANGL planar cell polarity protein 1 |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| WDR7 | WD repeat domain 7 |